Patents by Inventor Stephanie MCCALLA

Stephanie MCCALLA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Digital assay for quantifying and concentrating analytes
    Patent number: 10585091
    Abstract: Provided herein are methods, compositions, and devices for the identification and quantification of analytes, such as nucleic acids, proteins, cells or other biological samples. The methods, compositions, and devices are suited for accurate, portable analysis of small amounts of analyte.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: March 10, 2020
    Assignees: The University of Chicago, California Institute of Technology
    Inventors: Rustem F. Ismagilov, Stephanie McCalla, Travis Schlappi, Toan Huynh, Justin Rolando, Weishan Liu, Shencheng Ge, Jason E. Kreutz
  • Fluidic devices and systems for sample preparation or autonomous analysis
    Patent number: 9822356
    Abstract: The present invention relates to fluidic devices for preparing, processing, storing, preserving, and/or analyzing samples. In particular, the devices and related systems and methods allow for preparing and/or analyzing samples (e.g., biospecimen samples) by using one or more of capture regions and/or automated analysis.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: November 21, 2017
    Assignees: California Institute of Technology, SlipChip Corporation
    Inventors: Rustem F. Ismagilov, Feng Shen, Liang Li, Yu-Hsiang Hsu, Stefano Begolo, Mikhail Karymov, David Selck, Stephanie McCalla, Philip James Homewood
  • Differential effects of drugs on transport in a multi-layer 3D spheroid model
    Patent number: 9468680
    Abstract: Drugs are screened for affects on inhibiting efflux pumps and blocking gap junction communication in tumors by culturing cells to thereby form self-assembled spheroids and incubating the spheroids. Uptake of a substrate of the efflux pump and distribution of a substrate for the efflux pump within the spheroids is imaged to thereby select drugs that inhibit the efflux pump or do not block gap junction communication. Selected drugs can then be employed to treat a tumor.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: October 18, 2016
    Assignee: Brown University
    Inventors: Jeffrey R. Morgan, Toni-Marie Achilli, Anubhav Tripathi, Stephanie McCalla
  • DIGITAL ASSAY FOR QUANTIFYING AND CONCENTRATING ANALYTES
    Publication number: 20160266105
    Abstract: Provided herein are methods, compositions, and devices for the identification and quantification of analytes, such as nucleic acids, proteins, cells or other biological samples. The methods, compositions, and devices are suited for accurate, portable analysis of small amounts of analyte.
    Type: Application
    Filed: January 19, 2016
    Publication date: September 15, 2016
    Inventors: Rustem F. ISMAGILOV, Stephanie MCCALLA, Travis SCHLAPPI, Toan HUYNH, Justin ROLANDO, Weishan LIU, Shencheng GE, Jason E. KREUTZ