Patents by Inventor Stephanie Mercede

Stephanie Mercede has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diazaquinolones that inhibit prolyl hydroxylase activity
    Patent number: 8097620
    Abstract: Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: January 17, 2012
    Assignee: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Roland Burli, Jennifer E. Golden, Stephanie Mercede, Christopher M. Tegley
  • Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
    Patent number: 8048892
    Abstract: are useful as inhibitors of HIF prolyl hydroxylases where the definitions of the variables are provided herein.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: November 1, 2011
    Assignee: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Guo-Qiang Cao, Jennifer E. Golden, Stephanie Mercede, Tanya Peterkin, Anthony Reed, Christopher M. Tegley
  • Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
    Patent number: 7928139
    Abstract: Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: April 19, 2011
    Assignee: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Marian C. Bryan, Roland Burli, Guo-Qiang Cao, Michael J. Frohn, Jennifer E. Golden, Stephanie Mercede, Susana Neira, Tanya Peterkin, Alexander J. Pickrell, Anthony Reed, Christopher M. Tegley, Xiang Wang
  • NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF
    Publication number: 20100048572
    Abstract: Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
    Type: Application
    Filed: November 4, 2009
    Publication date: February 25, 2010
    Applicant: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Marian C. Bryan, Roland Burli, Guo-Qiang Cao, Michael J. Frohn, Jennifer E. Golden, Stephanie Mercede, Susana Neira, Tanya Peterkin, Alexander J. Pickrell, Anthony Reed, Christopher M. Tegley, Xiang Wang
  • Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
    Patent number: 7635715
    Abstract: Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: December 22, 2009
    Assignee: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Marian C. Bryan, Roland Burli, Guo-Qiang Cao, Michael J. Frohn, Jennifer E. Golden, Stephanie Mercede, Susana Neira, Tanya Peterkin, Alexander J. Pickrell, Anthony Reed, Christopher M. Tegley, Xiang Wang
  • Azaquinolone based compounds exhibiting prolyl hydroxylase Inhibitory activity, compositions, and uses thereof
    Publication number: 20090111806
    Abstract: are useful as inhibitors of HIF prolyl hydroxylases where the definitions of the variables are provided herein.
    Type: Application
    Filed: December 17, 2007
    Publication date: April 30, 2009
    Applicant: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Guo-Qiang Cao, Jennifer E. Golden, Stephanie Mercede, Tanya Peterkin, Anthony Reed, Christopher M. Tegley
  • Diazaquinolones that inhibit prolyl hydroxylase activity
    Publication number: 20090099171
    Abstract: Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.
    Type: Application
    Filed: May 2, 2008
    Publication date: April 16, 2009
    Applicant: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Roland Burli, Jennifer E. Golden, Stephanie Mercede, Christopher M. Tegley
  • Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
    Publication number: 20090093483
    Abstract: Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
    Type: Application
    Filed: December 17, 2007
    Publication date: April 9, 2009
    Applicant: Amgen Inc.
    Inventors: Jennifer R. Allen, Kaustav Biswas, Marian C. Bryan, Roland Burli, Guo-Qiang Cao, Michael J. Frohn, Jennifer E. Golden, Stephanie Mercede, Susana Neira, Tanya Peterkin, Alexander J. Pickrell, Anthony Reed, Christopher M. Tegley, Xiang Wang
  • Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof
    Publication number: 20070249605
    Abstract: This invention relates to new quinolone based compounds that exhibit prolyl hydroxylase inhibitory activity. This invention also relates to methods of increasing HIF levels or activity in a subject or treating a condition associated with HIF levels or activity in a subject by administering to the subject at least one quinolone based compound. This invention further involves assays for the detection of a hydroxyproline residue in a HIF molecule.
    Type: Application
    Filed: December 8, 2006
    Publication date: October 25, 2007
    Inventors: Jennifer Allen, Kaustav Biswas, Roland Burli, Jennifer Dao, Michael Frohn, Jennifer Golden, Randall Hungate, Robert Kurzeja, Stephanie Mercede, Kristine Muller, Susana Neira, Tanya Peterkin, Christopher Tegley, Violeta Yu