Patents by Inventor Stephanie Monnier

Stephanie Monnier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9163005
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: October 20, 2015
    Assignee: Novartis AG
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Publication number: 20140343087
    Abstract: Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
    Type: Application
    Filed: August 1, 2014
    Publication date: November 20, 2014
    Applicant: Novartis AG
    Inventors: Paul W. Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H. Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Patent number: 8865897
    Abstract: The invention relates to a new crystalline form of the acetate salt of which may be used, for example, for prevention or treatment of transplant rejection.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: October 21, 2014
    Assignee: Novartis AG
    Inventors: Piotr Karpinski, Stéphanie Monnier, Elias Ndzie, Dimitris Papoutsakis, Paul A Sutton
  • Patent number: 8829015
    Abstract: Crystalline forms of 4-methyl-N-3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: September 9, 2014
    Assignee: Novartis AG
    Inventors: Paul W. Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr “Peter” H. Karpinski, Raeann Wu, Stephanie Monnier, Jörg Brozio
  • Publication number: 20140038994
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Application
    Filed: October 11, 2013
    Publication date: February 6, 2014
    Applicant: Novartis AG
    Inventors: Paul W. MANLEY, Wen-Chung SHIEH, Paul Allen SUTTON, Piotr H. KARPINSKI, Raeann WU, Stéphanie MONNIER, Jörg BROZIO
  • Patent number: 8580806
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: November 12, 2013
    Assignee: Novartis AG
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Patent number: 8389537
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: March 5, 2013
    Assignee: Novartis AG
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Publication number: 20130023548
    Abstract: Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
    Type: Application
    Filed: August 3, 2012
    Publication date: January 24, 2013
    Inventors: Paul W. MANLEY, Wen-Chung SHIEH, Paul Allen SUTTON, Piotr H. KARPINSKI, Raeann WU, Stéphanie MONNIER, Jörg BROZIO
  • Publication number: 20120316142
    Abstract: Compounds of formula I in salt or solvate form, wherein W, Rx, Ry, R1, R2, R3, R4, R5, R6 and R7 and A have the meanings as indicated in the specification, are useful for treating diseases mediated by the ?2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Application
    Filed: May 4, 2012
    Publication date: December 13, 2012
    Inventors: Olivier LOHSE, Stéphanie MONNIER, Jean-Louis REBER
  • Publication number: 20120270891
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Application
    Filed: March 13, 2012
    Publication date: October 25, 2012
    Inventors: Paul W. Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H. Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Publication number: 20120208882
    Abstract: The invention describes novel pharmaceutically acceptable salt forms of camostat, processes for lyophilisation, taste-masked formulations, nebulised formulations and the use of each of the fore-going in the treatment of respiratory diseases, particularly cystic fibrosis and chronic obstructive pulmonary disease (COPD).
    Type: Application
    Filed: February 14, 2012
    Publication date: August 16, 2012
    Inventors: Henry Luke Danahay, Darren Mark LeGrand, David C. Tully, Jennifer Leslie Harris, Silvia Heuerding, Dilraj Singh, Janet Catherine Maas, Juergen Roettele, Jean-Louis Reber, Stéphanie Monnier
  • Patent number: 8198450
    Abstract: Compounds of formula I in salt or solvate form, wherein W, Rx, Ry, R1, R2, R3, R4, R5, R6 and R7 and A have the meanings as indicated in the specification, are useful for treating diseases mediated by the ?2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: June 12, 2012
    Assignee: Novartis AG
    Inventors: Olivier Lohse, Stephanie Monnier, Jean-Louis Reber
  • Patent number: 8163904
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: April 24, 2012
    Assignees: Novartis AG, Novartis Pharma GmbH
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Patent number: 8119841
    Abstract: This invention relates to crystal forms of aliskiren hemifumarate and various embodiments related thereto, e.g. pharmaceutical preparations, processes for the manufacture of the crystal forms, pharmaceuticals uses and the like. The crystal forms have particularly advantageous properties e.g. they are useful in the manufacture of blood-pressure lowering pharmaceutical preparations and the like.
    Type: Grant
    Filed: November 5, 2007
    Date of Patent: February 21, 2012
    Assignee: Novartis AG
    Inventors: Frank Stowasser, Stephanie Monnier
  • Publication number: 20110275685
    Abstract: The present invention relates to salts, polymorphs and hydrates of the kinesin inhibitor compound N-((S)-3-amino-4-fluorobutyl)-N-((R)-1-(1-benzlyl-4-(2,5-difluorophenyl)-1H-imidazol-2-yl)-2,2-dimethylpropyl)-2-hydroxyacetamide, processes to prepare such salts, polymorphs and hydrates and a liquid formulation comprising at least one of these salts, polymorphs and hydrates.
    Type: Application
    Filed: January 25, 2010
    Publication date: November 10, 2011
    Inventors: Michael Mutz, Jean-Louis Reber, Stephanie Monnier
  • Publication number: 20110112121
    Abstract: The present invention relates to pharmaceutical compositions of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide, to the use of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide and compositions of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide in therapeutic applications, especially indications with a dysregulation/overexpression of VEFG, (neo)-vascularisation and VEGF driven angiogenesis and to methods for manufacturing such compositions, the invention further relates to specific forms of 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide and to the manufacturing and use of such forms. The present invention also relates to a new process to produce 6-(6-hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide.
    Type: Application
    Filed: June 30, 2010
    Publication date: May 12, 2011
    Inventors: Joerg BERGHAUSEN, Claire HAUG, Michael HERBIG, Bin HU, Stéphane JONAT, Rajender LELETI, Josef Gottfried MEINGASSNER, Stéphanie MONNIER, Matthias NAPP, Mahavir PRASHAD, Anton STÜTZ, Ranjit THAKUR
  • Publication number: 20100048716
    Abstract: This invention relates to crystal forms of aliskiren hemifumarate and various embodiments related thereto, e.g. pharmaceutical preparations, processes for the manufacture of the crystal forms, pharmaceuticals uses and the like. The crystal forms have particularly advantageous properties e.g. they are useful in the manufacture of blood-pressure lowering pharmaceutical preparations and the like.
    Type: Application
    Filed: November 5, 2007
    Publication date: February 25, 2010
    Inventors: Frank Stowasser, Stephanie Monnier
  • Publication number: 20100041884
    Abstract: The invention relates to a new crystalline form of the acetate salt of, 3-(1.H.-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione, which may be used for example for transplantation.
    Type: Application
    Filed: October 18, 2007
    Publication date: February 18, 2010
    Inventors: Piotr Karpinski, Stéphanie Monnier, Elias Ndzie, Dimitris Papoutsakis, Paul A. Sutton
  • Publication number: 20100010039
    Abstract: New polymorphic crystal form of (R)-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one maleate designated crystal form Qalpha that is useful in the treatment of inflammatory or obstructive airways diseases. A method for preparing crystal form Qalpha is also described.
    Type: Application
    Filed: August 30, 2007
    Publication date: January 14, 2010
    Inventors: Olivier Lohse, Stephanie Monnier, Guido Jordine
  • Publication number: 20090325912
    Abstract: Compounds of formula I in salt or solvate form, wherein W, Rx, Ry, R1, R2, R3, R4, R5, R6 and R7 and A have the meanings as indicated in the specification, are useful for treating diseases mediated by the ?2-adrenoreceptor. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Application
    Filed: July 2, 2007
    Publication date: December 31, 2009
    Inventors: Olivier Lohse, Stéphanie Monnier, Jean-Louis Reber