Patents by Inventor Stephanie Rae HENNEK
Stephanie Rae HENNEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11920186Abstract: Methods for imaging are described, including, but not limited to a method comprising: (1) contacting a sample being tested for the presence of one or more targets with one or more target-specific binding partners, wherein each target-specific binding partner is linked to a docking strand, and wherein target-specific binding partners of different specificity are linked to different docking strands, (2) optionally removing unbound target-specific binding partners, (3) contacting the sample with antigen-bound imager strands and antigen-specific binding partners linked (directly or indirectly) to optical labels, wherein the antigen-bound imager strands have complementarity to a docking strand, directly or indirectly, and wherein each antigen-specific binding partner is linked to one or more optical labels, and wherein antigen-specific binding partners of different specificity are linked to distinct optical labels, (4) optionally removing unbound antigen-bound imager strands and/or antigen-specific binding partnerType: GrantFiled: February 10, 2022Date of Patent: March 5, 2024Assignee: Ultivue, Inc.Inventors: Stephanie Rae Hennek, Mael Manesse
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Publication number: 20230384295Abstract: A method for testing a sample for the presence of one or more targets comprises multiplexed catalyzed reporter deposition (CARD) is provided.Type: ApplicationFiled: August 15, 2023Publication date: November 30, 2023Applicant: Ultivue, Inc.Inventors: Mark Bobrow, Stephanie Rae Hennek, Mael Manesse
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Patent number: 11761955Abstract: A method for testing a sample for the presence of one or more targets comprises multiplexed catalyzed reporter deposition (CARD) is provided.Type: GrantFiled: June 6, 2019Date of Patent: September 19, 2023Assignee: Ultivue, Inc.Inventors: Mark Bobrow, Stephanie Rae Hennek, Mael Manesse
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Patent number: 11754562Abstract: The present application provides certain advantageous ways of conducting multiplexed imaging.Type: GrantFiled: August 13, 2020Date of Patent: September 12, 2023Assignee: Ultivue, Inc.Inventors: Stephanie Rae Hennek, Mael Manesse, Abdul Mohammed, Xi Chen, Michael Jules Natan
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Publication number: 20220356509Abstract: Methods for multiplexed target detection are disclosed. Signal amplification in multiplexed solid-phase phase target detection methods are disclosed.Type: ApplicationFiled: July 2, 2020Publication date: November 10, 2022Applicant: Ultivue, Inc.Inventors: Kevin HWANG, Mark BOBROW, Stephanie Rae HENNEK, Mael MANESSE
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Publication number: 20220162669Abstract: Methods for imaging are described, including, but not limited to a method comprising: (1) contacting a sample being tested for the presence of one or more targets with one or more target-specific binding partners, wherein each target-specific binding partner is linked to a docking strand, and wherein target-specific binding partners of different specificity are linked to different docking strands, (2) optionally removing unbound target-specific binding partners, (3) contacting the sample with antigen-bound imager strands and antigen-specific binding partners linked (directly or indirectly) to optical labels, wherein the antigen-bound imager strands have complementarity to a docking strand, directly or indirectly, and wherein each antigen-specific binding partner is linked to one or more optical labels, and wherein antigen-specific binding partners of different specificity are linked to distinct optical labels, (4) optionally removing unbound antigen-bound imager strands and/or antigen-specific binding partnerType: ApplicationFiled: February 10, 2022Publication date: May 26, 2022Applicant: Ultivue, Inc.Inventors: Stephanie Rae HENNEK, Mael MANESSE
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Patent number: 11279968Abstract: Methods for imaging are described, including, but not limited to a method comprising: (1) contacting a sample being tested for the presence of one or more targets with one or more target-specific binding partners, wherein each target-specific binding partner is linked to a docking strand, and wherein target-specific binding partners of different specificity are linked to different docking strands, (2) optionally removing unbound target-specific binding partners, (3) contacting the sample with antigen-bound imager strands and antigen-specific binding partners linked (directly or indirectly) to optical labels, wherein the antigen-bound imager strands have complementarity to a docking strand, directly or indirectly, and wherein each antigen-specific binding partner is linked to one or more optical labels, and wherein antigen-specific binding partners of different specificity are linked to distinct optical labels, (4) optionally removing unbound antigen-bound imager strands and/or antigen-specific binding partnerType: GrantFiled: February 12, 2019Date of Patent: March 22, 2022Assignee: Ultivue, Inc.Inventors: Stephanie Rae Hennek, Mael Manesse
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Publication number: 20200371097Abstract: The present application provides certain advantageous ways of conducting multiplexed imaging.Type: ApplicationFiled: August 13, 2020Publication date: November 26, 2020Applicant: Ultivue, Inc.Inventors: Stephanie Rae HENNEK, Mael MANESSE, Abdul MOHAMMED, Xi CHEN, Michael Jules NATAN
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Publication number: 20200256867Abstract: The present application provides certain advantageous ways of conducting multiplexed imaging.Type: ApplicationFiled: February 19, 2020Publication date: August 13, 2020Applicant: Ultivue, Inc.Inventors: Stephanie Rae HENNEK, Mael MANESSE, Abdul MOHAMMED, Xi CHEN, Michael Jules NATAN
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Publication number: 20190376956Abstract: A method for testing a sample for the presence of one or more targets comprises multiplexed catalyzed reporter deposition (CARD) is provided.Type: ApplicationFiled: June 6, 2019Publication date: December 12, 2019Inventors: Mark BOBROW, Stephanie Rae HENNEK, Mael MANESSE
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Publication number: 20190177767Abstract: Methods for imaging are described, including, but not limited to a method comprising: (1) contacting a sample being tested for the presence of one or more targets with one or more target-specific binding partners, wherein each target-specific binding partner is linked to a docking strand, and wherein target-specific binding partners of different specificity are linked to different docking strands, (2) optionally removing unbound target-specific binding partners, (3) contacting the sample with antigen-bound imager strands and antigen-specific binding partners linked (directly or indirectly) to optical labels, wherein the antigen-bound imager strands have complementarity to a docking strand, directly or indirectly, and wherein each antigen-specific binding partner is linked to one or more optical labels, and wherein antigen-specific binding partners of different specificity are linked to distinct optical labels, (4) optionally removing unbound antigen-bound imager strands and/or antigen-specific binding partnerType: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Applicant: Ultivue, Inc.Inventors: Stephanie Rae HENNEK, Mael MANESSE
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Publication number: 20190120767Abstract: A super-resolution fluorescence microscopy method comprises (a) providing a drift compensation marker, wherein (i) the drift compensation marker comprises a coated plasmonic particle; (ii) the drift compensation marker comprises an anisotropic plasmonic particle; and/or (iii) the drift compensation marker comprises a plasmonic particle comprising at least one reporter molecule on the surface of the plasmonic particle or on the surface of a coating; (b) performing super-resolution fluorescence microscopy; (c) using the drift compensation marker to improve the resolution of the super-resolution fluorescence microscopy.Type: ApplicationFiled: April 25, 2017Publication date: April 25, 2019Inventors: Michael Jules NATAN, Stephanie Rae HENNEK, Mael MANESSE
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Patent number: 10246738Abstract: Methods for imaging are described, including, but not limited to a method comprising: (1) contacting a sample being tested for the presence of one or more targets with one or more target-specific binding partners, wherein each target-specific binding partner is linked to a docking strand, and wherein target-specific binding partners of different specificity are linked to different docking strands, (2) optionally removing unbound target-specific binding partners, (3) contacting the sample with antigen-bound imager strands and antigen-specific binding partners linked (directly or indirectly) to optical labels, wherein the antigen-bound imager strands have complementarity to a docking strand, directly or indirectly, and wherein each antigen-specific binding partner is linked to one or more optical labels, and wherein antigen-specific binding partners of different specificity are linked to distinct optical labels, (4) optionally removing unbound antigen-bound imager strands and/or antigen-specific binding partnerType: GrantFiled: March 30, 2018Date of Patent: April 2, 2019Assignee: Ultivue, Inc.Inventors: Stephanie Rae Hennek, Mael Manesse
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Publication number: 20180372736Abstract: The present application provides compositions for multiplex imaging using labeled nucleic acid imaging agents.Type: ApplicationFiled: August 9, 2018Publication date: December 27, 2018Inventors: Stephanie Rae HENNEK, Mael MANESSE, Abdul MOHAMMED, Xi CHEN, Michael Jules NATAN
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Publication number: 20180348214Abstract: The present application provides compositions for multiplexed imaging using labeled nucleic acid imaging agents.Type: ApplicationFiled: August 9, 2018Publication date: December 6, 2018Inventors: Stephanie Rae HENNEK, Mael MANESSE, Abdul MOHAMMED, Xi CHEN, Michael Jules NATAN