Patents by Inventor Stephanie Stanford

Stephanie Stanford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220325261
    Abstract: Provided herein, inter alia, are PTPRS de-clustering agents and compositions and kits comprising the agents. Provided are methods of modulating extracellular matrix or decreasing fibroblast activity in a subject. Also provided are methods of treating subjects with or at risk of developing extracellular matrix diseases, fibroblast-mediated diseases, or autoimmune diseases.
    Type: Application
    Filed: June 23, 2022
    Publication date: October 13, 2022
    Inventors: Nunzio Bottini, Stephanie Stanford
  • Patent number: 11220486
    Abstract: Herein are provided, inter alia, compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and methods of using the same. In embodiments, the compound has a structure according to Formula (I-A).
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: January 11, 2022
    Assignees: LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
    Inventors: Nunzio Bottini, Jiwen Zou, Santhi R. Ganji, Stephanie Stanford, Anthony Pinkerton, Thomas D. Y. Chung, Michael Hedrick, Robert Ardecky
  • Publication number: 20200290977
    Abstract: Herein are provided, inter alia, compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and methods of using the same. In embodiments, the compound has a structure according to Formula (I-A).
    Type: Application
    Filed: February 18, 2020
    Publication date: September 17, 2020
    Inventors: Nunzio BOTTINI, Jiwen ZOU, Santhi R. GANJI, Stephanie STANFORD, Anthony PINKERTON, Thomas D. Y. CHUNG, Michael HEDRICK, Robert ARDECKY
  • Patent number: 10626094
    Abstract: Herein are provided, inter alia, compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and methods of using the same. In embodiments, the compound has a structure according to Formula (I-A).
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: April 21, 2020
    Assignees: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY
    Inventors: Nunzio Bottini, Jiwen Zou, Santhi R. Ganji, Stephanie Stanford, Anthony Pinkerton, Thomas D. Y. Chung, Michael Hedrick, Robert Ardecky
  • Patent number: 10604585
    Abstract: Presented is a method for treating inflammation and autoimmune diseases through the use of a phosphatase rheumatoid arthritis (PT-PRA) antagonist.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: March 31, 2020
    Assignees: La Jolla Institute for Allergy & Immunology, The Regents of the University of California
    Inventors: Nunzio Bottini, Gary Firestein, Stephanie Stanford
  • Patent number: 10385340
    Abstract: There are provided, inter alia, methods and compositions to treat autoimmune disease including invasiveness of fibroblast-like synoviocytes in rheumatoid arthritis.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: August 20, 2019
    Assignee: LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY
    Inventors: Nunzio Bottini, Stephanie Stanford
  • Publication number: 20170247340
    Abstract: Herein are provided, inter alia, compounds capable of modulating the level of activity of low molecular weight protein tyrosine phosphatase (LMPTP) and methods of using the same. In embodiments, the compound has a structure according to Formula (I-A).
    Type: Application
    Filed: October 14, 2015
    Publication date: August 31, 2017
    Inventors: Nunzio BOTTINI, Jiwen ZOU, Santhi R. GANJI, Stephanie STANFORD, Anthony PINKERTON, Thomas CHUNG, Michael HEDRICK, Robert ARDECKY
  • Publication number: 20170247469
    Abstract: Presented is a method for treating inflammation and autoimmune diseases through the use of a phosphatase rheumatoid arthritis (PT-PRA) antagonist.
    Type: Application
    Filed: September 9, 2015
    Publication date: August 31, 2017
    Inventors: Nunzio Bottini, Gary Firestein, Stephanie Stanford
  • Publication number: 20160122768
    Abstract: There are provided, inter alia, methods and compositions to treat autoimmune disease including invasiveness of fibroblast-like synoviocytes in rheumatoid arthritis.
    Type: Application
    Filed: November 10, 2015
    Publication date: May 5, 2016
    Inventors: Nunzio Bottini, Stephanie Stanford
  • Publication number: 20150175979
    Abstract: Provided herein, inter alia, are PTPRS de-clustering agents and compositions and kits comprising the agents. Provided are methods of modulating extracellular matrix or decreasing fibroblast activity in a subject. Also provided are methods of treating subjects with or at risk of developing extracellular matrix diseases, fibroblast-mediated diseases, or autoimmune diseases.
    Type: Application
    Filed: July 23, 2013
    Publication date: June 25, 2015
    Inventors: Nunzio Bottini, Stephanie Stanford
  • Publication number: 20130171164
    Abstract: Provided herein, inter alia, are compositions and methods of measuring levels of RPTP protein and RNA and treating subjects with certain diseases, such as autimmune diseases.
    Type: Application
    Filed: August 2, 2012
    Publication date: July 4, 2013
    Applicant: LA JOLLA INSTITUTE FOR ALLERGY & IMMUNOLOGY
    Inventors: Nunzio Bottini, Stephanie Stanford
  • Patent number: 8399213
    Abstract: The invention relates in general to tyrosine dephosphorylation. More specifically, the invention relates to methods and compositions for monitoring intracellular tyrosine dephosphorylation at the single cell level. The invention further relates to techniques that can be used as aid in the development of novel therapeutics, and monitor regulation of intracellular tyrosine phosphatase activity at the single cell level.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: March 19, 2013
    Assignee: University of Southern California
    Inventors: Nunzio Bottini, Stephanie Stanford, Amy Barrios, Sayantan Mitra
  • Publication number: 20100086957
    Abstract: The invention relates in general to tyrosine dephosphorylation. More specifically, the invention relates to methods and compositions for monitoring intracellular tyrosine dephosphorylation at the single cell level. The invention further relates to techniques that can be used as aid in the development of novel therapeutics, and monitor regulation of intracellular tyrosine phosphatase activity at the single cell level.
    Type: Application
    Filed: September 30, 2009
    Publication date: April 8, 2010
    Applicant: University of Southern California
    Inventors: Nunzio BOTTINI, Stephanie Stanford, Amy Barrios, Sayantan Mitra