Patents by Inventor Stephanie Van Horn

Stephanie Van Horn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • yhxB
    Patent number: 6340564
    Abstract: The invention provides yhxB polypeptides and polynucleotides encoding yhxB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yhxB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: January 22, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Karen Anne Ingraham, Chi Yong So, Stephanie Van Horn, Alison Francis Chalker, David John Holmes, Sanjoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Patrick Vernon Warren, Richard Lloyd Warren, Magdalena Zalacain
  • cDNA clone HDPBI30 that encodes a novel human 7-transmembrane receptor
    Publication number: 20010053536
    Abstract: HDPBI30 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HDPBI30 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
    Type: Application
    Filed: February 28, 2001
    Publication date: December 20, 2001
    Inventors: Ganesh Sathe, Stephanie Van Horn
  • ytgP
    Patent number: 6326172
    Abstract: The invention provides ytgP polypeptides and polynucleotides encoding ytgP polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ytgP polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: December 4, 2001
    Assignee: SmithKline Beecham Corp.
    Inventors: Sanjoy Biswas, Martin Karl Russel Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Patrick Vernon Warren, Stephanie Van Horn, Magdalena Zalacain
  • Respiratory nitrate reductase alpha subunit
    Patent number: 6316237
    Abstract: The invention provides respiratory nitrate reductase alpha subunit polypeptides and polynucleotides encoding respiratory nitrate reductase alpha subunit polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing respiratory nitrate reductase alpha subunit polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: November 13, 2001
    Assignee: SmithKline Beecham Corp.
    Inventors: Thomas B Mathie, Christopher M Traini, Stephanie Van Horn, Richard L Warren
  • ThdF
    Patent number: 6316211
    Abstract: The invention provides thdF polynucleotides encoding thdF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing thdF polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 26, 2000
    Date of Patent: November 13, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, Martin K R Burnham, Stephanie Van Horn, Magdalena Zalacain
  • Tarf
    Patent number: 6299883
    Abstract: The invention provides tarF polypeptides and DNA (RNA) encoding tarF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tarF polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: October 9, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Alison Frances Chalker, Stephanie Van Horn, Andrew Peter Fosberry, Michael Ovari
  • HFGAN72 receptor genomic DNA, variants thereof, and methods of use thereof in diagnostic applications
    Publication number: 20010025031
    Abstract: The invention relates to HFGAN72 receptor polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides and polypeptides, as well as variants thereof, for applications, which relate, in part, to research, diagnostic and clinical arts.
    Type: Application
    Filed: April 6, 2001
    Publication date: September 27, 2001
    Inventors: Catherine E. Ellis, Cheni Kwok, Nicola J. Bodsworth, Wendy Halsey, Stephanie Van Horn
  • FabF from Staphylococcus aureus
    Patent number: 6294357
    Abstract: The invention provides fabF polypeptides and polynucleotides encoding fabF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing fabF polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: September 25, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Howard Kallender, John T Lonsdale, Leslie Marie Palmer, Joshua West, Stephanie Van Horn
  • yfjO
    Publication number: 20010023064
    Abstract: The invention provides yfjO polypeptides and polynucleotides encoding yfjO polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yfjO polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: December 13, 2000
    Publication date: September 20, 2001
    Inventors: Sanjoy Biswas, Alexander Bryant, James Raymond Brown, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Stephanie Van Horn, Richard Lloyd Warren, Magdalena Zalacain
  • Galk promoter
    Patent number: 6291230
    Abstract: The invention provides galK promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: September 18, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc,
    Inventors: Magdalena Zalacain, Pan Fong Chan, David J. Holmes, Michael A. Lonetto, Stephanie Van Horn, Richard L. Warren, Jr.
  • Polynucleotides encoding an undercaprenyl diphosphate synthase of staphylococcus aureus
    Patent number: 6287810
    Abstract: The invention provides ups polypedes and polynucleotides encoding ups polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ups polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: September 11, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jianzhong Huang, Xinhe Jiang, Damien McDevitt, Stephanie Van Horn
  • dnaE
    Patent number: 6280990
    Abstract: The invention provides dnaE polypeptides and polynucleotides encoding dnaE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing dnaE polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: August 28, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Earl May, Stephanie Van Horn, Patrick V Warren, Richard L Warren
  • kdtB
    Patent number: 6277597
    Abstract: The invention provides kdtB polypeptides and polynucleotides encoding kdtB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing kdtB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 3, 1999
    Date of Patent: August 21, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Alison F Chalker, David J Holmes, Karen A Ingraham, Chi Young So, John P Throup, Stephanie Van Horn, Richard L Warren
  • tRNA methyltransferase from Streptococcus pneumoniae
    Patent number: 6245542
    Abstract: The invention provides yfjO polypeptides and polynucleotides encoding yfjO polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yfjO polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: June 12, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, Alexander Bryant, James Raymond Brown, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Stephanie Van Horn, Richard Lloyd Warren, Magdalena Zalacain
  • Human G protein coupled lysophosphatidic acid receptor
    Patent number: 6242572
    Abstract: HOFNH30 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HOFNH30 polypeptides and polynucleotides in terapy, and diagnostic assays for such.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: June 5, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Ping Tsui, Catherine E. Ellis, Ganesh M. Sathe, Stephanie Van Horn, Robert S. Ames, James J. Foley, Laura R. Fitzgerald, Henry M. Sarau, Jonathan K. Chambers
  • tktA
    Patent number: 6221631
    Abstract: The invention provides tktA polypeptides and polynucleotides encoding tktA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tktA polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: April 24, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jianzhong Huang, Xinhe Jiang, Damien McDevitt, Stephanie Van Horn
  • cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor
    Patent number: 6221627
    Abstract: HDPBI30 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HDPBI30 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: February 24, 1997
    Date of Patent: April 24, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Ganesh Sathe, Stephanie Van Horn
  • PcrA Helicase of Staphylococcus aureus
    Patent number: 6197546
    Abstract: The invention provides PcrA Helicase polypeptides and polynucleotides encoding PcrA Helicase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing PcrA Helicase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: March 6, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Damien McDevitt, Earl May, Annemarie St John, Stephanie Van Horn
  • Histidine kinase, 636 HK, of staphylococcus aureus
    Patent number: 6194174
    Abstract: The invention provides 636 HK polypeptides and polynucleotides encoding 636 HK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing 636 HK polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: February 27, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Martin K R Burnham, Leslie Marie Palmer, John Peter Throup, Stephanie Van Horn, Richard Lloyd Warren
  • FabF
    Patent number: 6168797
    Abstract: The invention provides fabF polypeptides and polynucleotides encoding fabF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing fabF polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 18, 1999
    Date of Patent: January 2, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, Martin K R Burnham, Jason C Fedon, David J Holmes, Karen A Ingraham, Howard Kallender, John T Lonsdale, Marie J Mazzulla, Karen M O'Dwyer, Leslie M Palmer, Chi Young So, Christopher M Traini, Glenn S Van Aller, Stephanie Van Horn, Magdalena Zalacain