Patents by Inventor Stephen A. Horne

Stephen A. Horne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof
    Patent number: 5872258
    Abstract: A process for making Fluconazole is provided comprising carrying out the following scheme of reaction: ##STR1##
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: February 16, 1999
    Assignee: Brantford Chemicals Inc.
    Inventors: Derrick L. J. Clive, Keshava Murthy, Gamini Weeratunga, Derek John Norris, Stephen Horne
  • Matrix metalloprotease inhibitors
    Patent number: 5773428
    Abstract: Compounds of formula (I): ##STR1## as single stereoisomers or mixtures thereof and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as interstitial collagenases, and are useful in the treatment of mammals having disease states alleviated by the inhibition of such matrix metalloproteases, for example arthritic diseases or bone resorption diseases, such as osteoporosis.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: June 30, 1998
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Arlindo Lucas Castelhano, Teng Jiam Liak, Stephen Horne, Alexander Krantz, Zhengyu Yuan, Jian Jeffrey Chen, Paul David Cannon, Hal Van Wart
  • Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof
    Patent number: 5633386
    Abstract: A process for making Fluconazole is provided comprising carrying out the following scheme of reaction: ##STR1##
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 27, 1997
    Assignee: ACIC (Canada) Inc.
    Inventors: Keshava Murthy, Gamini Weeratunga, Derek J. Norris, Stephen Horne, Derrick L. J. Clive