Patents by Inventor Stephen A. Parent

Stephen A. Parent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10934577
    Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: March 2, 2021
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, MERCK & CO., INC.
    Inventors: David S. Perlin, Steven Park, Cameron M. Douglas, Jennifer N. Kahn, Stephen A. Parent, Rosemarie Kelly
  • Publication number: 20170356034
    Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
    Type: Application
    Filed: May 22, 2017
    Publication date: December 14, 2017
    Applicants: Rutgers, The State University of New Jersey, Merck & Co., Inc.
    Inventors: David S. Perlin, Steven Park, Cameron M. Douglas, Jennifer N. Kahn, Stephen A. Parent, Rosemarie Kelly
  • Patent number: 9657334
    Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: May 23, 2017
    Assignees: Rutgers, The State University of New Jersey, Merck & Co., Inc.
    Inventors: David S. Perlin, Steven Park, Cameron M. Douglas, Jennifer N. Kahn, Stephen A. Parent, Rosemarie Kelly
  • Publication number: 20150125856
    Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 7, 2015
    Inventors: David S. Perlin, Steven Park, Cameron M. Douglas, Jennifer N. Kahn, Stephen A. Parent, Rosemarie Kelly
  • Patent number: 8753819
    Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: June 17, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: David S. Perlin, Steven Park, Cameron M. Douglas, Jennifer Nielsen Kahn, Stephen A. Parent, Rosemarie Kelly
  • Publication number: 20100075302
    Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
    Type: Application
    Filed: July 26, 2006
    Publication date: March 25, 2010
    Applicants: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, MERCK & CO.
    Inventors: David S. Perlin, Steven Park, Cameron M. Douglas, Jennifer Nielsen Kahn, Stephen A. Parent, Rosemarie Kelly
  • Patent number: 5324659
    Abstract: Disclosed is a process utilizing yeast mutants for identifying active FK-506 type immunosuppressants. The process utilizes Saccharomyces cerevisiae mutants containing an fkr1, fkr2, fkr3 mutant gene or mixture thereof, which are resistant to FK-506 but sensitive to rapamycin. These mutants can be used in a diagnostic procedure for identifying FK-506 and FK-506 type immunosuppressants and in screening assays for compounds and fermentation broths which exhibit FK-506 type immunosuppressive activity. Specifically disclosed are the new yeast mutants, Saccharomyces cerevisiae YKF093, (Merck Culture Collection No. MY 2088) ATCC No. 74055, containing an fkr3 mutant gene, Saccharomyces cerevisiae YKF 012, (Merck Culture Collection No. MY 2096) ATCC No. 74061, which contains an fkr1 mutant gene, Saccharomyces cerevisiae YFK 014, (Merck Culture Collection No. MY 2097) ATCC No. 74062 and YFK-023-17A (Merck Culture Collection No. MY 2098) ATCC No.
    Type: Grant
    Filed: July 31, 1992
    Date of Patent: June 28, 1994
    Assignee: Merck & Co., Inc.
    Inventors: Stephen A. Parent, Leonardo E. Brizuela, Gary L. Chrebet, Keith A. Bostian