Abstract: The invention relates to methods for treating prostate cancer by targeting the generation of splice variants of the androgen receptor. In one aspect, this can be achieved by targeting JMJD6 to reduce the production of androgen receptor splice variants. The invention finds particular use in the treatment of prostate cancer that is resistant to conventional androgen therapy.

Abstract: A fabric including microdenier fibers is provided, the microdenier fibers prepared by fibrillating a multicomponent, multilobal fiber including a contiguous core fiber component enwrapped by a multilobal sheath fiber component such that the sheath fiber component forms the entire outer surface of the multicomponent fiber, wherein the core fiber component and the multilobal sheath fiber component are sized such that the multicomponent, multilobal fiber can be fibrillated to expose the core fiber component and split the fiber into multiple microdenier fibers.

Abstract: A fabric including microdenier fibers is provided, the microdenier fibers prepared by fibrillating a multicomponent, multilobal fiber including a contiguous core fiber component enwrapped by a multilobal sheath fiber component such that the sheath fiber component forms the entire outer surface of the multicomponent fiber, wherein the core fiber component and the multilobal sheath fiber component are sized such that the multicomponent, multilobal fiber can be fibrillated to expose the core fiber component and split the fiber into multiple microdenier fibers.

Abstract: An air compressor unit having an enclosure with a base. A motor is rigidly mounted to the base, and the motor drives both an airend and an impeller. The airend is pivotally mounted with respect to the base. The airend is directly connected to a horizontal separator tank, and the separator tank supports the airend. The airend and separator tank comprise a single integrated unit, and the separator tank is pivotally mounted to the base. The motor is a dual shafted motor having a drive side shaft and a non-drive shaft extending from opposite ends of the motor. A drive system is coupled to the drive side shaft and transfers power from the motor to the airend. The drive system is a belt and pulley system, and the airend is pivoted with respect to the motor to adjust belt tension. The impeller is coupled to the non-drive side shaft.

Abstract: The subject matter disclosed herein relates generally to fabrics composed of micro-denier fibers wherein said fibers are formed as bicomponent fibrillated fiber. The energy is sufficient for fibrillating as well as entangling (bonding) the fibers. These fabrics can be woven or knitted and made from made from bicomponent islands in the sea fibers and filaments or can be nonwovens and formed by either spunbonding or through the use of bicomponent staple fibers formed into a web by any one of several means and bonded similarly to those used for the spunbonded filament webs.

Abstract: A method of producing a nonwoven fabric comprising spinning a set of bicomponent fibers which include an external fiber component and an internal fiber component. The external fiber enwraps said internal fiber and has a higher elongation to break value than the internal fiber and a lower melting temperature than the internal fiber component. The set of bicomponent fibers are positioned onto a web and thermally bonded to produce a nonwoven fabric.

Abstract: A bonded web of multi-component strands that include a first polymeric component and a second polymeric component is capable of overcoming a number of problems associated with nonwoven webs including both stickiness and blocking. The first polymeric component and second polymeric component are arranged in substantially distinct zones extending longitudinally along at least a portion of a length of the strands which make up the web with the second component containing a zone constituting at least a portion of the peripheral surface of the strand. The first polymeric component also has an elasticity which is greater than that of the second polymer component. A process producing elastomeric spunbonded nonwoven fabrics which utilizes the activation by incremental stretching of the strands is also provided.

Abstract: A bonded web of multi-component strands that include a first polymeric component and a second polymeric component is capable of overcoming a number of problems associated with nonwoven webs including both stickiness and blocking. The first polymeric component and second polymeric component are arranged in substantially distinct zones extending longitudinally along at least a portion of a length of the strands which make up the web with the second component containing a zone constituting at least a portion of the peripheral surface of the strand. The first polymeric component also has an elasticity which is greater than that of the second polymer component. A process producing elastomeric spunbonded nonwoven fabrics which utilizes the activation by incremental stretching of the strands is also provided.