Patents by Inventor STEPHEN ABBOTT

STEPHEN ABBOTT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microtubule associated protein Tau (MAPT) iRNA agent compositions and methods of use thereof
    Patent number: 12516322
    Abstract: The disclosure relates to double stranded ribonucleic acid interference (dsRNAi) agents and compositions targeting a microtubule-associated protein tau (MAPT) gene, as well as methods of inhibiting expression of a MAPT gene and methods of treating subjects having a MAPT-associated disease or disorder, e.g., Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, or other tauopathies, using such dsRNAi agents and compositions.
    Type: Grant
    Filed: December 7, 2023
    Date of Patent: January 6, 2026
    Assignee: Alnylam Pharmaceuticals, Inc.
    Inventors: Jonathan Edward Farley, Mark K. Schlegel, James D. McIninch, Jeffrey Zuber, Adam Castoreno, Stephen Abbott, Joseph Barry
  • MICROTUBULE ASSOCIATED PROTEIN TAU (MAPT) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20240254487
    Abstract: The disclosure relates to double stranded ribonucleic acid interference (dsRNAi) agents and compositions targeting a microtubule-associated protein tau (MAPT) gene, as well as methods of inhibiting expression of a MAPT gene and methods of treating subjects having a MAPT-associated disease or disorder, e.g., Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, or other tauopathies, using such dsRNAi agents and compositions.
    Type: Application
    Filed: December 7, 2023
    Publication date: August 1, 2024
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: JONATHAN EDWARD FARLEY, MARK K. SCHLEGEL, JAMES D. MCININCH, JEFFREY ZUBER, ADAM CASTORENO, STEPHEN ABBOTT, JOSEPH BARRY