Patents by Inventor Stephen Ackland

Stephen Ackland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anhydride modified cantharidin analogues useful in the treatment of cancer
    Publication number: 20060030616
    Abstract: Anhydride modified cantharidin analogues useful in the treatment of certain forms of cancer also methods for the screening for anti-cancer activity of these analogues and/or their ability to sensitise cancer cells to cancer treatment. The modified cantharidin analogues have structure (I) or (II), wherein R1, R2, R3 and R4 are H, aryl or alkyl; X is O, N or S; Y is O, S, NH, NR; R is alkyl or aryl; A and B are H or CH3; W and Z are CHOH or C?O. These compounds inhibit protein phosphatase.
    Type: Application
    Filed: September 30, 2005
    Publication date: February 9, 2006
    Inventors: Adam McCluskey, Jennette Sakoff, Stephen Ackland, Alistair Sim
  • Protein phosphate inhibitors
    Publication number: 20040209934
    Abstract: The present invention relates to modulators of cell cycle regulation and, in particular, to a protein phosphatase inhibitor which can interfere with the cell cycle; processes for the production of the inhibitor; and uses of the inhibitor, in particular in the treatment of disease, such as cancer.
    Type: Application
    Filed: May 13, 2004
    Publication date: October 21, 2004
    Inventors: Adam McCluskey, Jennette Sakoff, Stephen Ackland
  • Anhydride modified cantharidin analogues useful in the treatment of cancer
    Publication number: 20040110822
    Abstract: Anhydride modified cantharidin analogues useful in the treatment of certain forms of cancer also methods for the screening for anti-cancer activity of these analogues and/or their ability to sensitise cancer cells to cancer treatment. The modified cantharidin analogues have structure (I) or (II), wherein R1, R2, R3 and R4 are H, aryl or alkyl; X is O, N or S; Y is O, S, NH, NR; R is alkyl or aryl; A and B are H or CH3; W and Z are CHOH or C═O. These compounds inhibit protein phosphatase.
    Type: Application
    Filed: November 7, 2003
    Publication date: June 10, 2004
    Applicant: The University of Newcastle Research Associates
    Inventors: Adam McCluskey, Jennette A. Sakoff, Stephen Ackland, Alistair T.R. Sim