Abstract: The disclosure provides a system and method for attaching audio clips to text messages to allow the conveyance of emotion through sound. The audio clips can include vocals, instruments, and/or a combination of both. The audio clips can be manually or automatically selected for sending via a text message. In one example, a method of sending text messages disclosed herein includes: (1) selecting an audio clip that corresponds to text of a text message from a user, (2) connecting the audio clip with the text message, and (3) delivering the text message to a recipient.

Abstract: Disclosed are co-polymers which are produced from reactive monomer mixtures and which have both high refractive index and a high Abbe number. These materials are well suited for use as implantable ophthalmic devices and have a refractive index which may be edited through application of energy. When used for an intraocular lens, the high refractive index allows for a thin lens which compresses to allow a small incision size.

Abstract: Disclosed are co-polymers which are produced from reactive monomer mixtures and which have both high refractive index and a high Abbe number. These materials are well suited for use as implantable ophthalmic devices and have a refractive index which may be edited through application of energy. When used for an intraocular lens, the high refractive index allows for a thin lens which compresses to allow a small incision size.

Abstract: Disclosed is slip-on footwear with a concealable heel strap that is padded. Suitably, the padding of the padded heel strap is convertible into a pull-tab whenever the heel strap is concealed.

Abstract: Disclosed is slip-on footwear with a concealable heel strap that is padded. Suitably, the padding of the padded heel strap is convertible into a pull-tab whenever the heel strap is concealed.

Abstract: Example systems and methods are provided to determine the size and/or mass of a particle, such as a nanoparticle for example, deterministically (i.e., non-statistically). At least two resonances of the same radial order, having the same angular momentum number l but different azimuthal numbers m (?l<m<l) are excited in a WGM resonator. The particle's latitude angle on the WGM resonator is located using a ratio of detected resonance wavelength shifts. Finally, at least one of (A) the particle's size, and (B) the particle's mass, is determined from the latitude angle of the particle.

Abstract: An interactive medical system and methods, involving a processor operable by way of a set of executable instructions stored in a non-transitory memory device, the set of executable instructions enabling the processor to receive, analyze, and transmit data in relation to a database, a plurality of medical equipment, and a display device, whereby an integrated medical protocol can be provided to the display device based on the analyzed data. The system is readily transportable for use in critical medical situations.

Abstract: Example systems and methods are provided to determine the size and/or mass of a particle, such as a nanoparticle for example, deterministically (i.e., non-statistically). At least two resonances of the same radial order, having the same angular momentum number/but different azimuthal numbers m (?l<m<l) are excited in a WGM resonator. The particle's latitude angle on the WGM resonator is located using a ratio of detected resonance wavelength shifts. Finally, at least one of (A) the particle's size, and (B) the particle's mass, is determined from the latitude angle of the particle.

Abstract: A syringe-based whispering gallery mode sensor includes a syringe including an assembly provided its needle, the assembly including (1) an optical carrier having a reflective distal end, and (2) at least one resonator coupled with the optical carrier. This sensor may be provided in a system including a light source, a light detector, and a data analysis component. A method for determining the presence or concentration of a target substance in body fluid may be performed using such a system.

Abstract: Methods using light force to fabricate WGM sensors including microresonators having target receptors selectively and substantially provided at only ribbon area of the microresonators.

Abstract: A sensor for determining the presence or concentration of a target entity in a medium is described, and includes (a) an optical waveguide; (b) a microresonator optically coupled with the optical waveguide such that light within the optical waveguide induces a resonant mode within the microresonator at an equator region (or a mode volume); and (c) at least one plasmonic nanoparticle adsorbed onto a surface area of the microresonator within the equator region (or the mode volume) such that light inducing a resonant mode within the microresonator also causes a plasmonic resonance in the at least one plasmonic nanoparticle. Detection methods for using such sensors are also described. Finally, methods, involving the use of carousel forces, for fabricating such sensors are also described.

Abstract: A sensor for determining the presence or concentration of a target entity in a medium is described, and includes (a) an optical waveguide; (b) a microresonator optically coupled with the optical waveguide such that light within the optical waveguide induces a resonant mode within the microresonator at an equator region (or a mode volume); and (c) at least one plasmonic nanoparticle adsorbed onto a surface area of the microresonator within the equator region (or the mode volume) such that light inducing a resonant mode within the microresonator also causes a plasmonic resonance in the at least one plasmonic nanoparticle. Detection methods for using such sensors are also described. Finally, methods, involving the use of carousel forces, for fabricating such sensors are also described.

Abstract: A syringe-based whispering gallery mode sensor includes a syringe including an assembly provided its needle, the assembly including (1) an optical carrier having a reflective distal end, and (2) at least one resonator coupled with the optical carrier. This sensor may be provided in a system including a light source, a light detector, and a data analysis component. A method for determining the presence or concentration of a target substance in body fluid may be performed using such a system.

Abstract: Applying a strong static DC electric field to supersaturated aqueous glycine solutions resulted in the nucleation of the ? polymorph attributed to the electric-field induced orientation of the highly polar glycine molecules in large preexisting solute clusters, helping them organize into a crystalline structure. A method to induce crystallization and to prepare polymorphs and/or morphologies of materials by using a static electric field to cause nucleation and crystal growth to occur in a supersaturated solution in such a way as to obtain a crystal structure that would not normally appear without the use of the static electric field. Aqueous glycine solutions were prepared by combining solid glycine and water. Supersaturated solutions were generated by heating the tubes to 62-64° C. and holding them at that temperature in an ultrasonicator overnight. Once the glycine was completely dissolved, the solutions were slowly cooled to room temperature.

Abstract: Methods using light force to fabricate WGM sensors including microresonators having target receptors selectively and substantially provided at only ribbon area of the microresonators.

Abstract: A spectroscopic technique for high-sensitivity, label free DNA quantification uses a shift in an optical resonance (whispering gallery mode, WGM) excited in a micron-sized optical cavity (e.g., a silica sphere) to detect and measure nucleic acids. The surface of the silica sphere is chemically modified with oligonucleotides. Hybridization to the target DNA leads to a red-shift of the optical resonance wavelength. The sensitivity of this resonance technique is higher than most optical single-pass devices such as surface plasmon resonance biosensors. Each microsphere can be identified by its unique resonance wavelength. Specific, multiplexed DNA detection may be provided by using two or more microspheres. The multiplexed signal from two or more microspheres illustrates that a single nucleotide mismatch in an 11-mer oligonucleotide can be discriminated with a high signal-to-noise of 54.

Abstract: Lactam polymers has been modified with sodium borohydride (NaBH4) to yield lactam polymers bearing hydroxyl functional groups. These functional groups are useful for the covalent attachment of reactive groups, fluorescent probes, antimicrobial agents, bioactive factors, and drugs. The resulting as components for medical devices, specifically ophthalmic devices and more specifically contact lenses. Hydrogels based on these polymers are also useful for biomedical applications in the areas of drug delivery, tissue engineering, and implantable devices.

Abstract: The use of whispering gallery mode (WGM) evanescent waves to detect adsorption of molecules to the surface of microsphere sensors and more particularly to the utilization of a high refractive index surface layer to increase the sensitivity thereof. The present invention examines the sensor capability of WGM in a dielectric sphere coated with a thin uniform dielectric layer of a high refractive index. Among the utilities of such a modified resonator for the sensing are to have an evanescent field of a different penetration depth without using a non-silica based microsphere or changing the laser wavelength, to further enhance the sensitivity by drawing the optical field of WGM into the coating layer, and to realize the same relative shifts for WGM of different radial modes, thus eliminating ambiguities in the measurement of a refractive index change in the surrounding medium.

Abstract: The present invention relates to wettable silicone hydrogels comprising the reaction product of at least one siloxane containing component and at least one reactive, hydrophilic polymeric internal wetting agent. The present invention further relates to silicone hydrogel contact lenses comprising at least one oxygen permeable component, and an amount of reactive, hydrophilic polymeric internal wetting agent sufficient to impart wettability to said device.

Abstract: Lactam polymers has been modified with sodium borohydride (NaBH4) to yield lactam polymers bearing hydroxyl functional groups. These functional groups are useful for the covalent attachment of reactive groups, fluorescent probes, antimicrobial agents, bioactive factors, and drugs. The resulting as components for medical devices, specifically ophthalmic devices and more specifically contact lenses. Hydrogels based on these polymers are also useful for biomedical applications in the areas of drug delivery, tissue engineering, and implantable devices.