Abstract: A web service gateway system includes a host application execution environment including one or more processors, a memory, and a gateway interface configured to receive a gateway copybook input from a host application. The gateway copybook includes input data including a pointer identifying a memory location of a request structure copybook, and output data including a pointer identifying a memory location of a response structure copybook. A gateway program receives the gateway copybook from the gateway interface and invokes a proxy web service with a request using the request structure copybook. The proxy web service maps data from the request structure copybook to web protocol format data, and invokes a target web service with the web protocol format data. The gateway program returns to the gateway interface a response that is based upon a response the gateway program receives from the proxy web service and uses the response structure copybook.

Abstract: A web service gateway provides a single web service API to host applications for accessing any web service. The single web service API may be available across all host execution environments; facilitate client service by handling target service addresses and security credentials; avoid significant new training for existing host application developers; and be a low-cost addition to existing infrastructure. The web service gateway supports multiple execution domains and multiple test environments.

Abstract: The present disclosure presents methods, systems, and devices for encrypting and comparing genomic data. The comparison of genomic data allows the owner of the data to ensure security of the data even when the party conducting the comparison is beyond the control of the owner of the data. The encryption of the genomic data enables the transmission, storage, and use of the genomic data in a secure media.

Abstract: Disclosed are methods, apparatus, systems, and computer readable storage media for managing applications on a computing device. A computing device may receive allowed application data indicating applications that are launchable by a base application. A user interface with one or more selections of the applications may be displayed at a display of the computing device. The computing device may receive input data indicating a selection of an application. Identifier data associated with the base application and selection data associated with the application may be provided to the application.

Abstract: The present disclosure presents methods, systems, and devices for encrypting and comparing genomic data. The comparison of genomic data allows the owner of the data to ensure security of the data even when the party conducting the comparison is beyond the control of the owner of the data. The encryption of the genomic data enables the transmission, storage, and use of the genomic data in a secure media.

Abstract: The present disclosure presents methods, systems, and devices for encrypting and comparing genomic data. The comparison of genomic data allows the owner of the data to ensure security of the data even when the party conducting the comparison is beyond the control of the owner of the data. The encryption of the genomic data enables the transmission, storage, and use of the genomic data in a secure media.

Abstract: The present disclosure presents methods, systems, and devices for encrypting and comparing genomic data. The comparison of genomic data allows the owner of the data to ensure security of the data even when the party conducting the comparison is beyond the control of the owner of the data. The encryption of the genomic data enables the transmission, storage, and use of the genomic data in a secure media.

Abstract: Disclosed are methods, apparatus, systems, and computer readable storage media for managing applications on a computing device. A computing device may receive allowed application data indicating applications that are launchable by a base application. A user interface with one or more selections of the applications may be displayed at a display of the computing device. The computing device may receive input data indicating a selection of an application. Identifier data associated with the base application and selection data associated with the application may be provided to the application.

Abstract: A pressure vessel may be formed from a thermally processed metal tube. The thermally processed metal tube may be seamless with a large length to diameter ratio. End portions of the thermally processed metal tube may be formed at a first temperature below the lower critical temperature by a load less than about the ultimate stress of the metal. After forming, the end portion may be thermally reconditioned at a second temperature below the lower critical temperature to relieve stress and approach similar material properties as the thermally processed metal tube.

Abstract: The present invention relates to a novel and useful method for assaying compounds and agents for their ability to decrease or inhibit the activity of hematopoietic prostaglandin D2 synthase (hPGDS). Specifically, the present invention relates to assays for measuring the potency, specificity and toxicity of hPGDS inhibitors.

Abstract: Methods of determining the potency, specificity, and toxicity of microsomal prostaglandin E2 synthase inhibitors are provided that utilize one cell-based assay system.

Abstract: The present invention relates to new processes useful for separating whey proteins from whey protein-containing solutions using a novel anion exchanger which comprises a water insoluble, hydrophilic, water swellable, hydroxy (C2–C4) alkylated and cross-linked regenerated cellulose, derivatized with quaternary amino (QA) groups where the level of substitution of the QA groups is 1.4 milli-equivalents per dry gram of anion exchanger (meq/g) or greater.

Abstract: Methods of determining the potency, specificity, and toxicity of microsomal prostaglandin E2 synthase inhibitors are provided that utilize one cell-based assay system.

Abstract: The present invention is related to a new quaternary amino (QA) anion exchanger comprising QA derivatized, hydroxy (C2-C4) alkylated and cross-linked regenerated cellulose, in which the level of derivitization with the QA-groups is 1.4 milli-equivalents per dry gram (meq/g) or greater.

Abstract: This invention is directed to a process for producing an immunoglobulin enriched whey protein fraction from whey protein solutions. More particularly, it relates to the production of a whey protein fraction enriched in immunoglobulin, and optionally a whey protein isolate, using a cation exchanger under selected conditions. The selected conditions require overloading the cation exchanger with potentially absorbable protein which causes the exchanger to adsorb preferentially whey proteins other than immunoglobulin. The invention is also directed to the products produced by the process of the invention.

Abstract: The present invention provides a new quaternary amino (QA) anion exchanger comprising QA derivatised, hydroxy (C2-C4) alkylated and cross-linked regenerated cellulose, in which the level of derivatisation with the QA-groups is 1.4 meg/g or greater.

Abstract: The present invention provides new processes useful for separating whey proteins from whey protein-containing solutions using a novel anion exchanger which comprises a water insoluble, hydrophilic, water swellable, hydroxy (C2-C4) alkylated and cross-linked regenerated cellulose, derivatised with quaternary amino (QA) groups, wherein the level of substitution of the QA groups is 1.4 milli-equivalents per dry gram of anion exchanger (meq/g) or greater.

Abstract: The present invention is related to a method for the purification of glycomacropeptide (GMP) with an amino acid composition containing no greater that 0.5% (w/w) phenylalanine, comprising the steps of contacting a GMP-containing feedstock with a first anion exchanger under conditions to adsorb the GMP, eluting the adsorbed GMP from the anion exchanger and removing impurities from the GMP-containing eluate by either: (i) contacting the GMP-containing eluate with a cation exchanger in conditions under which the impurities in the eluate are adsorbed onto the cation exchanger, or (ii) precipitating the impurities in GMP-containing eluate using conditions in which the GMP remains i solution, or (iii) contacting the GMP-containing eluate with a second anion exchanger in conditions under which the impurities in the eluate are adsorbed onto the anion exchanger, and recovering the GMP from whichever one or more of the steps (i), (ii) or (iii) was used.

Abstract: A preparative method of isolating a preselected whey protein or group of whey proteins from a solution is provided. The method comprises the following steps: (a) contacting a whey protein solution with the preselected ion exchanger for a time and at a temperature sufficient to enable the preselected whey protein to be adsorbed; wherein the whey protein solution has (1) a protein content in the range of about 5% to about 20% by weight, (2) a pH of a preselected level, which is the level at which the preselected whey protein or group of whey proteins selectively binds to the preselected ion exchanger, and (3) a reduced ionic strength; and (b) recovering either or both of the following: (1) the whey protein component adsorbed in step (a), and (2) the breakthrough whey protein component not adsorbed in step (a).

Abstract: The invention relates to the use of a sulphated ion exchanger to selectively remove lipoproteins from blood plasma or serum. Although the attraction between sulphate groups and proteins has long been recognized it has now unexpectedly been found that cationic ion exchangers whose ion exchange capacity is provided by sulphate groups bind lipoproteins selectively in presence of other plasma or serum proteins and ions when they are equilibrated with solutions containing divalent cations and the same cation is added to the plasma or serum. Types of ion exchanger matrices and applications of the utlity are discussed.