Patents by Inventor Stephen B. del Cardayre

Stephen B. del Cardayre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods Of Producing Omega-Hydroxylated Fatty Acid Derivatives
    Publication number: 20250019731
    Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
    Type: Application
    Filed: March 5, 2024
    Publication date: January 16, 2025
    Inventors: Andreas W. SCHIRMER, Haibo WANG, Stephen B. DEL CARDAYRE, Zhihao HU, Louis G. HOM, Baolong ZHU, Cindy CHANG, Emanuela E. POPOVA
  • Semisynthetic routes to organic compounds
    Patent number: 12188068
    Abstract: The present disclosure relates to chemo-enzymatic processes for the preparation of lactones (including, e.g., macrolactones, ?-lactones, and ?-lactones) and/or macrocyclic ketones, which are compounds of industrial value, for example, for use as fragrance ingredients. The chemo-enzymatic processes combine the in vivo microbial production of fatty acid derivatives and the subsequent ex vivo synthetic transformation of the fatty acid derivatives to provide the lactones and macrocyclic ketones.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: January 7, 2025
    Assignee: Genomatica, Inc.
    Inventors: Stephen B. Del Cardayre, Andreas W. Schirmer, Myong Ko, Haibo Wang
  • Methods of producing omega-hydroxylated fatty acid derivatives
    Patent number: 11981952
    Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: May 14, 2024
    Assignee: Genomatica, Inc.
    Inventors: Andreas W. Schirmer, Haibo Wang, Stephen B. Del Cardayre, Zhihao Hu, Louis G. Hom, Baolong Zhu, Cindy Chang, Emanuela E. Popova
  • SYSTEMS AND METHODS OF MAKING OIL FROM MICROORGANISMS
    Publication number: 20240060101
    Abstract: SYSTEMS AND METHODS OF MAKING OIL FROM MICROORGANISMS Described herein are systems and methods of manufacturing an oil comprising a triacylglyceride. The systems and methods may comprise: (a) providing an oleaginous microorganism; (b) culturing the oleaginous microorganism in a medium comprising a carbon source, wherein the carbon source comprises ethanol at greater than 50% by weight; and (c) harvesting the oil from the oleaginous microorganism when the oil is at least 25% by weight of the oleaginous microorganism.
    Type: Application
    Filed: August 18, 2023
    Publication date: February 22, 2024
    Inventors: Jeff NOBBS, Jay D. KEASLING, Stephen B. DEL CARDAYRE
  • Recombinant microorganisms for the production of fatty amines
    Patent number: 11814660
    Abstract: The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof. Further contemplated are cultured recombinant host cells as well as methods of producing fatty amines by employing these host cells.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: November 14, 2023
    Assignee: Genomatica, Inc.
    Inventors: Stephen B. Del Cardayre, Louis G. Hom
  • SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS
    Publication number: 20210310033
    Abstract: The present disclosure relates to processes that combine microbial production of organic intermediates and subsequent synthetic transformation to provide compounds of industrial value, including compounds used in fragrances.
    Type: Application
    Filed: April 13, 2021
    Publication date: October 7, 2021
    Inventors: Stephen B. DEL CARDAYRE, Andreas W. SCHIRMER, Myong KO, Haibo WANG
  • Production Of Fatty Acids And Derivatives Thereof
    Publication number: 20210171987
    Abstract: Compositions and methods for production of fatty alcohols using recombinant microorganisms are provided as well as fatty alcohol compositions produced by such methods.
    Type: Application
    Filed: October 19, 2020
    Publication date: June 10, 2021
    Inventors: Jay D. KEASLING, Zhihao HU, Chris SOMERVILLE, George CHURCH, David BERRY, Lisa C. FRIEDMAN, Andreas SCHIRMER, Shane BRUBAKER, Stephen B. DEL CARDAYRE
  • Microbial Production Of Fatty Amines
    Publication number: 20210164002
    Abstract: The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof. Further contemplated are cultured recombinant host cells as well as methods of producing fatty amines by employing these host cells.
    Type: Application
    Filed: December 14, 2020
    Publication date: June 3, 2021
    Inventors: Stephen B. DEL CARDAYRE, Louis G. HOM
  • Chemo-enzymatic process
    Patent number: 11008597
    Abstract: The present disclosure relates to processes that combine microbial production of organic intermediates and subsequent synthetic transformation to provide compounds of industrial value, including compounds used in fragrances.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: May 18, 2021
    Assignee: Genomatica, Inc.
    Inventors: Stephen B. Del Cardayre, Andreas W. Schirmer, Myong Ko, Haibo Wang
  • Microbial production of alkanolamides and amidoamines and uses thereof
    Patent number: 10975402
    Abstract: The disclosure relates to a recombinant microorganism engineered to express an enzyme which catalyzes the conversion of a primary amine and an acyl thioester to a fatty amide. The disclosure further encompasses a method of producing a fatty amide by culturing the recombinant microorganism in the presence of a carbon source.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: April 13, 2021
    Assignee: GENOMATICA, INC.
    Inventors: Jason J. Lutes, Stephen B. Del Cardayre
  • METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES
    Publication number: 20210071212
    Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
    Type: Application
    Filed: June 29, 2020
    Publication date: March 11, 2021
    Applicant: Genomatica, Inc.
    Inventors: Andreas W. Schirmer, Haibo Wang, Stephen B. Del Cardayre, Zhihao Hu, Louis G. Hom, Baolong Zhu, Cindy Chang, Emanuela E. Popova
  • Recombinant microorganisms for the production of fatty amines
    Patent number: 10900057
    Abstract: The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof. Further contemplated are cultured recombinant host cells as well as methods of producing fatty amines by employing these host cells.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: January 26, 2021
    Assignee: Genomatica, Inc.
    Inventors: Stephen B. Del Cardayre, Louis G. Hom
  • Production of fatty acids and derivatives thereof
    Patent number: 10844406
    Abstract: Compositions and methods for production of fatty alcohols using recombinant microorganisms are provided as well as fatty alcohol compositions produced by such methods.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: November 24, 2020
    Assignee: Genomatica, Inc.
    Inventors: Jay D. Keasling, Zhihao Hu, Chris Somerville, George Church, David Berry, Lisa C. Friedman, Andreas Schirmer, Shane Brubaker, Stephen B. Del Cardayre
  • MICROBIAL PRODUCTION OF ALKANOLAMIDES AND AMIDOAMINES AND USES THEREOF
    Publication number: 20200232001
    Abstract: The disclosure relates to a recombinant microorganism engineered to express an enzyme which catalyzes the conversion of a primary amine and an acyl thioester to a fatty amide. The disclosure further encompasses a method of producing a fatty amide by culturing the recombinant microorganism in the presence of a carbon source.
    Type: Application
    Filed: August 22, 2019
    Publication date: July 23, 2020
    Applicant: REG Life Sciences, LLC
    Inventors: Jason J. LUTES, Stephen B. Del Cardayre
  • Methods of producing omega-hydroxylated fatty acid derivatives
    Patent number: 10711288
    Abstract: The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: July 14, 2020
    Assignee: GENOMATICA, INC.
    Inventors: Andreas W. Schirmer, Haibo Wang, Stephen B. Del Cardayre, Zhihao Hu, Louis G. Hom, Baolong Zhu, Cindy Chang, Emanuela E. Popova
  • Microbial production of alkanolamides and amidoamines and uses thereof
    Patent number: 10392637
    Abstract: The disclosure relates to a recombinant microorganism engineered to express an enzyme which catalyzes the conversion of a primary amine and an acyl thioester to a fatty amide. The disclosure further encompasses a method of producing a fatty amide by culturing the recombinant microorganism in the presence of a carbon source.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: August 27, 2019
    Assignee: REG Life Sciences, LLC
    Inventors: Jason J. Lutes, Stephen B. Del Cardayre
  • MICROBIAL PRODUCTION OF FATTY AMINES
    Publication number: 20190032097
    Abstract: The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof. Further contemplated are cultured recombinant host cells as well as methods of producing fatty amines by employing these host cells.
    Type: Application
    Filed: December 5, 2014
    Publication date: January 31, 2019
    Inventors: Stephen B. DEL CARDAYRE, Louis G. HOM
  • MICROBIAL PRODUCTION OF ALKANOLAMIDES AND AMIDOAMINES AND USES THEREOF
    Publication number: 20170292120
    Abstract: The disclosure relates to a recombinant microorganism engineered to express an enzyme which catalyzes the conversion of a primary amine and an acyl thioester to a fatty amide. The disclosure further encompasses a method of producing a fatty amide by culturing the recombinant microorganism in the presence of a carbon source.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 12, 2017
    Inventors: Jason J. LUTES, Stephen B. DEL CARDAYRE
  • PRODUCTION OF FATTY ACIDS AND DERIVATIVES THEREOF
    Publication number: 20170275651
    Abstract: Compositions and methods for production of fatty alcohols using recombinant microorganisms are provided as well as fatty alcohol compositions produced by such methods.
    Type: Application
    Filed: March 7, 2017
    Publication date: September 28, 2017
    Inventors: Jay D. Keasling, Zhihao Hu, Chris Somerville, George Church, David Berry, Lisa C. Friedman, Andreas Schirmer, Shane Brubaker, Stephen B. DEL CARDAYRE
  • Production of fatty acids and derivatives thereof
    Patent number: 9598706
    Abstract: Compositions and methods for production of fatty alcohols using recombinant microorganisms are provided as well as fatty alcohol compositions produced by such methods.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: March 21, 2017
    Assignee: REG LIFE SCIENCES, LLC
    Inventors: Jay D. Keasling, Zhihao Hu, Chris Somerville, George Church, David Berry, Lisa C. Friedman, Andreas Schirmer, Shane Brubaker, Stephen B. Del Cardayre