Patents by Inventor Stephen Baird
Stephen Baird has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11162944Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is an arabinose ester of a mycolic acid or an analogue thereof.Type: GrantFiled: August 12, 2016Date of Patent: November 2, 2021Assignee: DIAGNOSTIG LTD.Inventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al-Dulayymi, Mohsin Omar Mohammed
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Patent number: 10809260Abstract: A method of determining whether an individual is infected with mycobacteria. The method comprising the steps of (a) providing a system which comprises at least two different mycolic-acid derived antigens; (b) introducing a sample obtained from the individual into the system and into contact with each of the at least two different mycolic-acid derived antigens; and (c) detecting the presence or absence of the binding of a biomarker in the sample with each antigen in the system. The method may be particularly suitable for determining the presence or absence of a disease antibody indicative of infection with any disease caused by infection with mycobacteria, for example tuberculosis, leprosy, pulmonary disease, burili ulcer, Johne's disease and bovine tuberculosis. A kit and device are also described. The present invention may provide an over the counter device to allow individuals to check on a routine basis that they have normal immune responses.Type: GrantFiled: August 13, 2015Date of Patent: October 20, 2020Assignee: DIAGNOSTIG LTDInventors: Mark Stephen Baird, Christopher David Gwenin, Vanessa Valerie Gwenin, Alison Jones
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Patent number: 10782293Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is a mycolic acid wax ester derived antigen.Type: GrantFiled: August 12, 2016Date of Patent: September 22, 2020Assignee: DIAGNOSTIG LTDInventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al Dulayymi, Salam Ghafour Taher
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Publication number: 20200172015Abstract: A light sensing rear-view mirror assembly for reducing glare during night driving includes a commercial vehicle. A pair of rear view mirrors is provided and each of the rear view mirrors is each mounted on a respective one of a driver's side and a passenger's side of the commercial vehicle. A pair of control circuits is each coupled to a respective one of the rear view mirrors. A pair of dimming units is each coupled to a respective one of the rear view mirrors. Each of the dimming units is electrically coupled to the control circuit on the respective rear view mirror. Moreover, each of the dimming units automatically reducing an intensity of light reflected in the respective rear view mirror wherein each of the dimming units is configured to enhance a driver's night vision.Type: ApplicationFiled: December 4, 2018Publication date: June 4, 2020Inventor: Stephen Baird
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Publication number: 20190250160Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is a mycolic acid wax ester derived antigen.Type: ApplicationFiled: August 12, 2016Publication date: August 15, 2019Inventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al Dulayymi, Salam Ghafour Taher
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Publication number: 20180231547Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is an arabinose ester of a mycolic acid or an analogue thereof.Type: ApplicationFiled: August 12, 2016Publication date: August 16, 2018Inventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al-Dulayymi, Mohsin Omar Mohammed
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Patent number: 9945852Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising: (a) linking an antigen to colloidal gold to provide a gold-antigen species; (b) contacting the gold-antigen species with the sample; (c) adding a diagnosis agent to the sample; and (d) observing the color of the sample.Type: GrantFiled: May 4, 2012Date of Patent: April 17, 2018Assignee: Arcis Biotechnology Holdings LimitedInventors: Christopher David Gwenin, Mark Stephen Baird, Vanessa Valerie Gwenin, Mark Pitts
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Publication number: 20170248595Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising the steps of (a) providing a porous substrate which carries an antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a composition comprising a secondary antibody; and (d) observing the substrate. The method may enable a very quick, simple test to be carried out to determine whether or not a particular sample contains a biomarker, for example an antibody indicative of infection with a mycobacterial disease. A kit and a device for determining the presence or absence in a sample of a biomarker are also described.Type: ApplicationFiled: August 13, 2015Publication date: August 31, 2017Inventors: Mark Stephen Baird, Christopher David Gwenin, Vanessa Valerie Gwenin, Joanne Louise Hacking, Mark Pitts
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Publication number: 20170242005Abstract: A method of determining whether an individual is infected with mycobacteria. The method comprising the steps of (a) providing a system which comprises at least two different mycolic-acid derived antigens; (b) introducing a sample obtained from the individual into the system and into contact with each of the at least two different mycolic-acid derived antigens; and (c) detecting the presence or absence of the binding of a biomarker in the sample with each antigen in the system. The method may be particularly suitable for determining the presence or absence of a disease antibody indicative of infection with any disease caused by infection with mycobacteria, for example tuberculosis, leprosy, pulmonary disease, burili ulcer, Johne's disease and bovine tuberculosis. A kit and device are also described. The present invention may provide an over the counter device to allow individuals to check on a routine basis that they have normal immune responses.Type: ApplicationFiled: August 13, 2015Publication date: August 24, 2017Inventors: Mark Stephen Baird, Christopher David Gwenin, Vanessa Valerie Gwenin, Alison Jones
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Patent number: 9506921Abstract: A method of determining the presence or absence in a sample of a biomarker indicative of exposure to mycobacteria, the method comprising: (a) providing a substrate carrying a mycolic acid derived antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a fluorophore species; (d) creating an evanescent wave at the boundary of the substrate and the sample; (e) detecting the presence or absence of fluorescence.Type: GrantFiled: March 30, 2012Date of Patent: November 29, 2016Assignee: Bangor UniversityInventors: Christopher David Gwenin, Mark Stephen Baird
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Patent number: 9447010Abstract: The present invention discloses a simple method for transforming cashew nut shell liquid into an active herbicidal composition.Type: GrantFiled: February 13, 2013Date of Patent: September 20, 2016Assignee: BANGOR UNIVERSITYInventors: Viacheslav Vitalievich Tverezovskiy, Radek Messias Braganca, Frank Arthur Howard, Spencer Matthew Gould, Paul Anthony Fowler, Mark Stephen Baird
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Patent number: 9206213Abstract: A method of preparing a compound of formula (III): (M)x-(S)y-(M?)z??(III) wherein x is from 1 to 6, y is from 1 to 12, z is from 0 to 10, each M and each M? is independently a mycolic acid residue including a ?-hydroxy acid moiety and each S is a monosaccharide unit; the method comprising reacting one or more mycolic acids with one or more saccharide units wherein the hydroxyl group of each ?-hydroxy acid moiety is protected prior to reaction with the one or more saccharide units.Type: GrantFiled: December 9, 2013Date of Patent: December 8, 2015Assignee: Bangor UniversityInventors: Mark Stephen Baird, Juma'a Raheem Najeem Al Dulayymi, Johan Adriaan Marc Grooten, Seppe Vander Beken, Maximilliano Maza-Inglesias
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Publication number: 20150018569Abstract: The present invention discloses a simple method for transforming cashew nut shell liquid into an active herbicidal composition.Type: ApplicationFiled: February 13, 2013Publication date: January 15, 2015Applicant: BANOR UNIVERSIITYInventors: Viacheslav Vitalievich Tverezovskiy, Radek Messias Braganca, Frank Arthur Howard, Spencer Matthew Gould, Paul Anthony Fowler, Mark Stephen Baird
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Patent number: 8889894Abstract: A compound of formula (I) for use in the treatment of a disease of the immune system; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; R1 is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 40 carbon atoms; each of R2, R3 and R4 is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, arylalkylene or alkylarylene moiety having from 1 to 40 carbon atoms; each of X, Y and Z is independently selected from an optionally-substituted alkylene, alkenylene, alkenylene, arylene, alkylarylene, cycloalkylene, ketone, ester, amide, imide, imine, thioether, ether, thioester and thioketone; and P is selected from hydrogen, an alkyl group, a sugar residue, or a metal, phosphonium or ammonium species; wherein at least one of X, Y and Z includes a moiety selected from cyclopropyl, C=A, C-AH and C—OR5; wherein R5 is alkyl or haloalkyl, and A is O,Type: GrantFiled: April 22, 2009Date of Patent: November 18, 2014Assignees: Bangor University, Universiteit GentInventors: Mark Stephen Baird, Juma′ a Raheem Najeem Al-Dulayy-mi, Cornelias Theunissen, Gani Koza, Seppe Vander-Beken, Johan Adriaan Marc Grooten
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Publication number: 20140178434Abstract: A method of preparing a compound of formula (III): (M)x-(S)y-(M?)z??(III) wherein x is from 1 to 6, y is from 1 to 12, z is from 0 to 10, each M and each M? is independently a mycolic acid residue including a ?-hydroxy acid moiety and each S is a monosaccharide unit; the method comprising reacting one or more mycolic acids with one or more saccharide units wherein the hydroxyl group of each ?-hydroxy acid moiety is protected prior to reaction with the one or more saccharide units.Type: ApplicationFiled: December 9, 2013Publication date: June 26, 2014Applicant: Bangor UniversityInventors: Mark Stephen Baird, Juma'a Raheem Najeem Al Dulayymi, Johan Adriaan Marc Grooten, Seppe Vander Beken, Maximilliano Maza-Inglesias
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Patent number: 8728515Abstract: A compound of formula (I) for use as an adjuvant in vaccination; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; R1 is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 40 carbon atoms; each of R2, R3 and R4 is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, arylalkylene or alkylarylene moiety having from 1 to 40 carbon atoms; each of X, Y and Z is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, alkylarylene or cycloalkylene, ketone, ester, amide, imide, imine, thioether, ether, thioester, thioketone; and P is selected from hydrogen, an alkyl group, a sugar residue, or a metal, phosphonium or ammonium species; wherein at least one of X, Y and Z includes a moiety selected from cyclopropyl, C=A, C-AH and C—OR5; wherein R5 is alkyl or haloalkyl, and A is S, O or NR6, wherein R6Type: GrantFiled: April 22, 2009Date of Patent: May 20, 2014Assignees: Bangor University, Universiteit GentInventors: Mark Stephen Baird, Juma' a Raheem Najeem Al-Dulayymi, Cornelia Theunissen, Gani Koza, Seppe Vander Beken, Johan Adriaan Marc Grooten
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Publication number: 20140127709Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising: (a) linking an antigen to colloidal gold to provide a gold-antigen species; (b) contacting the gold-antigen species with the sample; (c) adding a diagnosis agent to the sample; and (d) observing the colour of the sample.Type: ApplicationFiled: May 4, 2012Publication date: May 8, 2014Applicant: Bangor UniversityInventors: Christopher David Gwenin, Mark Stephen Baird, Vanessa Valerie Gwenin, Mark Pitts
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Publication number: 20140051599Abstract: A method of determining the presence or absence in a sample of a biomarker indicative of exposure to mycobacteria, the method comprising: (a) providing a substrate carrying a mycolic acid derived antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a fluorophore species; (d) creating an evanescent wave at the boundary of the substrate and the sample; (e) detecting the presence or absence of fluorescence.Type: ApplicationFiled: March 30, 2012Publication date: February 20, 2014Applicant: Bangor UniversityInventors: Christopher David Gwenin, Mark Stephen Baird
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Patent number: 8530683Abstract: A method of obtaining a solid component rich in a petroselinic compound from the seed of a plant of the Apiaceae or Araliaceae families, the method comprising: (a) treating a portion of the seed of the plant with an extraction solvent; and (b) inducing formation of the solid component.Type: GrantFiled: December 22, 2008Date of Patent: September 10, 2013Assignee: Bangor UniversityInventors: Mark Stephen Baird, David Preskett
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Publication number: 20120296073Abstract: A process of obtaining a saponin-rich component from a plant of the Araliaceae family, the process comprising the steps of: (a) treating a portion of the plant with an extraction solvent in which saponin-containing compounds are soluble; and (b) treating the portion of plant or the extract obtained therefrom to remove fatty acid residues from said portion of plant or extract thereof.Type: ApplicationFiled: May 11, 2012Publication date: November 22, 2012Applicant: BANGOR UNIVERSITYInventors: Mark Stephen Baird, David Preskett