Abstract: An integrity monitoring system for a lined pipeline is provided for monitoring the integrity of a polymer liner in a host pipe. Methods and apparatus are described by which a lined pipeline is provided with such an integrity monitoring system. Sensor cable is able to bridge a joint between sections of lined pipe, for example by routing the sensor cable across the joint via a channel in an electrofusion fitting or by connecting successive lengths of sensor cable via pass-throughs in an electrofusion fitting. Advantageously, the sensor cable is disposed within a continuous annulus between linings and host pipes, and the continuous annulus is maintained across pipe joints using electrofusion fittings.

Abstract: The present disclosure provides a method for automatic sampling of immune cells from a biological fluid sample deposited in a well of a microwell plate. The microwell plate is placed on a shaker having a magnetic adapter including at least one magnet. The magnet causes red blood cells (RBCs) bound to magnetic beads to be attracted to and migrate to a wall of the well. The shaker is then operated to shake the microwell plate such that the immune cells are substantially isolated from the RBCs in a region of the well. A sample probe is then lowered into the region of the well to withdraw a portion of the sample containing the immune cells.

Abstract: The disclosed embodiments describe systems and methods for approving a transfer. User information may be accessed for a plurality of users in a group. Account information for a plurality of disparate electronic accounts associated with the group may be accessed. The disparate electronic accounts may be integrated and managed through a central entitlements engine. Permissions information associated with the user information and the account information may be accessed. A transfer request for an account in the plurality of disparate electronic accounts may be received from a first user device associated with a first user of the plurality of users. The transfer request may be sent to a second user device associated with a second user of the plurality of users. An electronic indication of an approval of the transfer request may be received. The permissions information may be modifiable by input from the second user device.

Abstract: The present disclosure provides a method for automatic sampling of immune cells from a biological fluid sample, e.g., whole blood, deposited in a well of a microwell plate. The microwell plate is placed on a shaker having a magnetic adapter including at least one magnet. The magnet causes red blood cells (RBCs) bound to magnetic beads to be attracted to and migrate to a wall of the well. The shaker is then operated to shake the microwell plate such that the immune cells are substantially isolated from the RBCs in a region of the well. A sample probe is then lowered into the region of the well to withdraw a portion of the sample containing the immune cells.

Abstract: Methods and apparatus for making lined pipelines utilize lined pipes and fittings attached to the ends of the lined pipes. Castellations are formed on the inner surfaces of the fittings. First and second ends of a fit-up sleeve are inserted into the fittings on the ends of first and second lined pipes and the first and second ends of the fit-up sleeve force portions of the liners within the pipes into engagement with the castellations on the inner surfaces of the fittings. The fittings are then attached to each other to join the first and second lined pipes together.

Abstract: Methods and apparatus for making lined pipelines in which pipes are joined together. Within the joint there is a fit-up sleeve which forces liners against respective pipes and provides corresponding seals. Other seals can be provided by inserting sealing rings which force different portions of the liners against different portions of the pipes. The fit-up sleeve and sealing rings force the liners against castellations which prevent movement of the liners. The fit-up sleeve may cooperate with insertion rims on the pipes to provide very accurate spacing, or touching edges which can be desirable if automatic welding is employed. The seals provided by the fit-up sleeve also eliminate backdraughts and assist welding operations. Furthermore, the fit-up sleeve permits pigging through the pipe joint and therefore along the length of the resulting lined pipeline. It is foreseen that the need for CRA components and CRA welding can be largely if not wholly dispensed with.

Abstract: Methods and apparatus for making lined pipelines in which pipes are joined together by attaching fittings at their ends and joining the fittings together. Within the joint there is a fit-up sleeve which forces liners against respective fittings and provides corresponding seals. Other seals can be provided by inserting sealing rings which force different portions of the liners against different portions of the fittings. The fit-up sleeve and sealing rings may force the liners against castellations which prevent movement of the liners. The fit-up sleeve may cooperate with insertion rims on the fittings to provide very accurate spacing, or touching edges which can be desirable if automatic welding is employed. The seals provided by the fit-up sleeve also eliminate backdraughts and assist welding operations. Furthermore, the fit-up sleeve permits pigging through the pipe joint and therefore along the length of the resulting lined pipeline.

Abstract: An integrity monitoring system for a lined pipeline is provided for monitoring the integrity of a polymer liner in a host pipe. Methods and apparatus are described by which a lined pipeline is provided with such an integrity monitoring system. Sensor cable is able to bridge a joint between sections of lined pipe, for example by routing the sensor cable across the joint via a channel in an electrofusion fitting or by connecting successive lengths of sensor cable via pass-throughs in an electrofusion fitting. Advantageously, the sensor cable is disposed within a continuous annulus between linings and host pipes, and the continuous annulus is maintained across pipe joints using electrofusion fittings.

Abstract: A method creates a weld between a liner of a section of lined pipe and an electrofusion fitting. The fitting has at least one heating element, which is suitably disposed on or in an outer surface of the electrofusion fitting and is electrically isolated from an inner surface of the fitting. The method includes locating an end of the electrofusion fitting within an end of the section of lined pipe, locating an induction coil within a bore of the electrofusion fitting in the vicinity of the at least one heating element, and supplying electrical power to the induction coil to energise the at least one heating element by electromagnetic induction.

Abstract: An improved pipe liner and associated methods, including a method of manufacturing the improved pipe liner and a method of lining a host pipe with such a pipe liner. The invention solves the problem of gas permeation through a polymer liner in hydrocarbon service which can result in corrosion of the host pipe and can also cause liner collapse. Corrosion occurs due to contact between corrosive species and the host pipe itself. Gases (307) can also accumulate in an annulus between or within the liner (305) and the host pipe (303) and expand during operational de-pressurisation of the pipeline, causing collapse of the liner. The improved pipe liner comprises a barrier layer (311), which prevents permeation through the liner, surrounding an inner polymer pipe (305A) and optionally covered by an outer polymer pipe (305B).

Abstract: A method of creating a weld between a liner of a section of lined pipe and an electrofusion fitting. The fitting comprises at least one heating element, which is suitably disposed on or in an outer surface of the electrofusion fitting and is electrically isolated from an inner surface of the fitting. The method comprises locating an end of the electrofusion fitting within an end of the section of lined pipe, locating an induction coil within a bore of the electrofusion fitting in the vicinity of the at least one heating element, and supplying electrical power to the induction coil to energise the at least one heating element by electromagnetic induction.

Abstract: An integrity monitoring system for a lined pipeline is provided for monitoring the integrity of a polymer liner in a host pipe. Methods and apparatus are described by which a lined pipeline is provided with such an integrity monitoring system sensor cable is able to bridge a joint between sections of lined pipe, for example by routing the sensor cable across the joint via a channel in an electrofusion fitting or by connecting successive lengths of sensor cable via pass-throughs in an electrofusion fitting. Advantageously, the sensor cable is disposed within a continuous annulus between linings and host pipes, and the continuous annulus is maintained across pipe joints using electrofusion fittings.

Abstract: An improved pipe liner and associated methods, including a method of manufacturing the improved pipe liner and a method of lining a host pipe with such a pipe liner. The invention solves the problem of gas permeation through a polymer liner in hydrocarbon service which can result in corrosion of the host pipe and can also cause liner collapse. Corrosion occurs due to contact between corrosive species and the host pipe itself. Gases (307) can also accumulate in an annulus between or within the liner (305) and the host pipe (303) and expand during operational de-pressurisation of the pipeline, causing collapse of the liner. The improved pipe liner comprises a barrier layer (311), which prevents permeation through the liner, surrounding an inner polymer pipe (305A) and optionally covered by an outer polymer pipe (305B).

Abstract: Methods and apparatus for making lined pipelines in which pipes are joined together by attaching fittings at their ends and joining the fittings together. Within the joint there is a fit-up sleeve which forces liners against respective fittings and provides corresponding seals. Other seals can be provided by inserting sealing rings which force different portions of the liners against different portions of the fittings. The fit-up sleeve and sealing rings may force the liners against castellations which prevent movement of the liners. The fit-up sleeve may cooperate with insertion rims on the fittings to provide very accurate spacing, or touching edges which can be desirable if automatic welding is employed. The seals provided by the fit-up sleeve also eliminate backdraughts and assist welding operations. Furthermore, the fit-up sleeve permits pigging through the pipe joint and therefore along the length of the resulting lined pipeline.

Abstract: An integrity monitoring system for a lined pipeline is provided for monitoring the integrity of a polymer liner in a host pipe. Methods and apparatus are described by which a lined pipeline is provided with such an integrity monitoring system. Sensor cable is able to bridge a joint between sections at lined pipe, for example by routing the sensor cable across the joint via a channel in an electrofusion fitting or by connecting successive lengths of sensor cable via pass-throughs in an electrofusion fitting. Advantageously, the sensor cable is disposed within a continuous annulus between linings and host pipes, and the continuous annulus is maintained across pipe joints using electrofusion fittings.

Abstract: A method for automatic sampling of immune cells from a biological fluid sample, e.g., whole blood, deposited in a well of a microwell plate. The sample contains red blood cells (RBCs) and magnetic beads which are designed to bind to the RBCs. The microwell plate is placed on a shaker having a magnetic adapter including at least one magnet. The magnet causes the RBCs bound to the magnetic beads to be attracted to and migrate to a wall of the well (e.g., the bottom or side wall) and be held against the wall. The shaker is then operated to shake the microwell plate in a manner and for a time period so as to suspend substantially evenly or homogeneously the immune cells in the biological fluid sample within a region of the well but still retain the holding of the RBCs to the wall of the well such that the immune cells are substantially isolated from the RBCs in the region of the well.

Abstract: The disclosure provides example rinse station apparatus, cartridges, and methods for flow cytometry. The rinse station apparatus includes: (a) a cartridge docking station having a base with a recessed receptacle for a cartridge, a vertical support coupled to the base's first end and a top support coupled to the vertical support and cantilevered over the base, the top support has an opening that aligns with the cartridge's opening, (b) a locking arm coupled to the base's second end, the locking arm's free end has a ridge to cooperate with a detent coupled to the cartridge's rear wall to retain the cartridge in place, (c) a spring coupled to the vertical support's front face to apply force to the cartridge's front wall to bias the cartridge toward the locking arm, and (d) a load cell coupled to the base of the cartridge docking station, the load cell measure's the cartridge's weight.

Abstract: A flow cytometer module configured to be integrated with a liquid handling system is provided herein. The flow cytometer module includes (a) a flow cell, (b) a first fluidic pathway, (c) an inlet configured to receive a sample introduction device of the liquid handling system including one or more samples, (d) a second fluidic pathway in fluid communication with the first fluidic pathway, (e) a laser interrogation device configured to examine the one or more samples at a laser interrogation point in the second fluidic pathway, and (f) a controller in communication with the liquid handling system and configured to cause the flow cytometer module to perform functions comprising: (i) recording data from the laser interrogation device corresponding to a plurality of events as the one or more samples pass the laser interrogation point, and (ii) transmitting the data corresponding to the plurality of events to the liquid handling system.

Abstract: In order to reduce or remove the potential risk of heat damage in the absence of cooling jackets when joining lined pipe sections, each lined pipe section is provided with an insulatory sleeve which is disposed between the host pipe and the respective liner. The sleeves provide discrete thermal protection to the ends of the liners and, where applicable, electrofusion welds between an electrofusion fitting and the liners. The sleeves are first located in the ends of the host pipes which are then lined by drawing the liners through the host pipes via a reduction die to reduce their external diameter. The liners are then reverted towards their original dimensions resulting in a tight fitting against the internal surface of the host pipes and of the insulatory sleeves thereby compressing the insulation material.

Abstract: The disclosure provides example rinse station apparatus, cartridges, and methods for flow cytometry. The rinse station apparatus includes: (a) a cartridge docking station having a base with a recessed receptacle for a cartridge, a vertical support coupled to the base's first end and a top support coupled to the vertical support and cantilevered over the base, the top support has an opening that aligns with the cartridge's opening, (b) a locking arm coupled to the base's second end, the locking arm's free end has a ridge to cooperate with a detent coupled to the cartridge's rear wall to retain the cartridge in place, (c) a spring coupled to the vertical support's front face to apply force to the cartridge's front wall to bias the cartridge toward the locking arm, and (d) a load cell coupled to the base of the cartridge docking station, the load cell measure's the cartridge's weight.