Patents by Inventor Stephen Barnett Solomon

Stephen Barnett Solomon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11723709
    Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge-discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: August 15, 2023
    Assignee: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Govindarajan Srimathveeravalli, Stephen Barnett Solomon
  • Patent number: 11596788
    Abstract: An exemplary apparatus, can include, for example, a circulating tumor cell (CTC) treatment arrangement, a pump arrangement configured to circulate a fluid through the CTC treatment arrangement, and an electric field generator electrically connected to the CTC treatment arrangement, and configured to apply an electric field to the fluid circulating through the CTC treatment arrangement. The pump arrangement can be a peristaltic pump, which can be configured to continuously circulate the fluid through the CTC treatment arrangement. According to another exemplary embodiment of the present disclosure, method, system and computer-accessible medium can be provided for killing at least one circulating tumor cell (CTC). Using such exemplary embodiment, blood can be pumped from a body of a patient to an electroporation chamber inside of a CTC treatment arrangement. An electric field can be applied to the blood located in the electroporation chamber in order to kill the CTC.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: March 7, 2023
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Govindarajan Srimathveeravalli, Stephen Barnett Solomon
  • Publication number: 20210000527
    Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge-discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.
    Type: Application
    Filed: July 13, 2020
    Publication date: January 7, 2021
    Inventors: GOVINDARAJAN SRIMATHVEERAVALLI, STEPHEN BARNETT SOLOMON
  • Publication number: 20200289819
    Abstract: An exemplary apparatus, can include, for example, a circulating tumor cell (CTC) treatment arrangement, a pump arrangement configured to circulate a fluid through the CTC treatment arrangement, and an electric field generator electrically connected to the CTC treatment arrangement, and configured to apply an electric field to the fluid circulating through the CTC treatment arrangement. The pump arrangement can be a peristaltic pump, which can be configured to continuously circulate the fluid through the CTC treatment arrangement. According to another exemplary embodiment of the present disclosure, method, system and computer-accessible medium can be provided for killing at least one circulating tumor cell (CTC). Using such exemplary embodiment, blood can be pumped from a body of a patient to an electroporation chamber inside of a CTC treatment arrangement. An electric field can be applied to the blood located in the electroporation chamber in order to kill the CTC.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 17, 2020
    Inventors: Govindarajan SRIMATHVEERAVALLI, Stephen Barnett SOLOMON
  • Patent number: 10709491
    Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge-discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: July 14, 2020
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Govindarajan Srimathveeravalli, Stephen Barnett Solomon
  • Publication number: 20160184003
    Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge—discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.
    Type: Application
    Filed: August 6, 2014
    Publication date: June 30, 2016
    Inventors: Govindarajan Srimathveeravalli, Stephen Barnett Solomon