Patents by Inventor Stephen Besch

Stephen Besch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for measuring changes in cell volume
    Patent number: 8372600
    Abstract: A method and apparatus for measuring changes in cell volume generally includes introducing cells into a chamber having a volume between 2 and 100 times the volume of the introduced cell. A first electrically conductive extracellular fluid is introduced into the chamber and a current is applied. The voltage induced by said current flow is measured. The first fluid is exchanged with a second electrically conductive extracellular fluid and a current is applied. The voltage induced by said current flow is measured. The first induced voltage result and the second induced voltage result are used in conjunction with known voltages induced by such current flows to monitor changes in the volume corresponding to fluid flow between the cell and an extracellular fluid.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: February 12, 2013
    Assignee: The Research Foundation of State University of New York
    Inventors: Frederick Sachs, Zonglu Hua, Stephen Besch, Harsh Deep Chopra, Philip Gottlieb
  • Method and system for synchronous rectification
    Patent number: 7869972
    Abstract: The method and system of the present invention uses synchronous rectification and frequency domain analysis to remove the need for calibration of the A/D and D/A components. It is applicable to any sensor based measurement in which either the sensor can be excited with an AC voltage or current, or in which the signal can be modulated with an AC voltage or current.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: January 11, 2011
    Assignee: The Research Foundation of State University of New York
    Inventors: Stephen Besch, Frederick Sachs
  • Method And System For Synchronous Rectification
    Publication number: 20100188101
    Abstract: The method and system of the present invention uses synchronous rectification and frequency domain analysis to remove the need for calibration of the A/D and D/A components. It is applicable to any sensor based measurement in which either the sensor can be excited with an AC voltage or current, or in which the signal can be modulated with an AC voltage or current.
    Type: Application
    Filed: June 5, 2008
    Publication date: July 29, 2010
    Inventors: Stephen Besch, Frederick Sachs
  • Method and apparatus for measuring changes in cell volume
    Publication number: 20090233330
    Abstract: A method and apparatus for measuring changes in cell volume generally includes introducing cells into a chamber having a volume between 2 and 100 times the volume of the introduced cell. A first electrically conductive extracellular fluid is introduced into the chamber and a current is applied. The voltage induced by said current flow is measured. The first fluid is exchanged with a second electrically conductive extracellular fluid and a current is applied. The voltage induced by said current flow is measured. The first induced voltage result and the second induced voltage result are used in conjunction with known voltages induced by such current flows to monitor changes in the volume corresponding to fluid flow between the cell and an extracellular fluid.
    Type: Application
    Filed: February 25, 2009
    Publication date: September 17, 2009
    Applicant: The Research Foundation of State University of New York
    Inventors: Frederick Sachs, Zonglu Hua, Stephen Besch, Harsh Deep Chopra, Philip Gottlieb
  • Method and apparatus for measuring changes in cell volume
    Publication number: 20050239046
    Abstract: A method and apparatus for measuring changes in cell volume generally includes introducing cells into a chamber having a volume between 2 and 100 times the volume of the introduced cell. A first electrically conductive extracellular fluid is introduced into the chamber and a current is applied. The current flow is measured. The first fluid is exchanged with a second electrically conductive extracellular fluid and a current is applied. The current flow is measured. The first current flow result and the second current flow result are used in conjunction with known current flows to monitor changes in the volume corresponding to fluid flow between the cell and an extracellular fluid.
    Type: Application
    Filed: March 4, 2005
    Publication date: October 27, 2005
    Applicant: The Research Foundation of State University of New York
    Inventors: Frederick Sachs, Zonglu Hua, Stephen Besch, Harsh Chopra, Anthony Auerbach, Philip Gottlieb, Daniel Ateya