Patents by Inventor Stephen BLAKEMORE

Stephen BLAKEMORE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF DISEASES CHARACTERIZED BY OVEREXPRESSION OF ERYTHROPOIETIN-PRODUCING HEPATOCELLULAR RECEPTOR A2 (EPHA2)
    Publication number: 20230233698
    Abstract: The present invention relates to a Bicycle toxin conjugate BT5528, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof, and uses thereof.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 27, 2023
    Inventors: Gavin BENNETT, Stephen BLAKEMORE, Carly CAMPBELL, Michael RIGBY
  • INHIBITORS OF EZH2 AND METHODS OF USE THEREOF
    Publication number: 20230201212
    Abstract: The disclosure provides a method of treating cancer in a subject in need thereof including administering to the subject a therapeutically-effective amount of an enhancer of a zeste homolog 2 (EZH2) inhibitor. In certain embodiments of this method, the subject has one or more mutations, or exhibits a genetic profile, listed in Tables 1-5, and/or FIGS. 1-3.
    Type: Application
    Filed: June 13, 2018
    Publication date: June 29, 2023
    Inventors: Stephen BLAKEMORE, Scott Richard DAIGLE
  • INHIBITORS OF EZH2 AND METHODS OF USE THEREOF
    Publication number: 20220193084
    Abstract: The disclosure provides a method of treating cancer in a subject in need thereof including administering to the subject a therapeutically-effective amount of an enhancer of a zeste homolog 2 (EZH2) inhibitor. In certain embodiments of this method, the subject has one or more mutations in one or more sequences encoding a gene listed in Tables 1-9, Tables 17-19, and/or FIGS. 19-22.
    Type: Application
    Filed: December 9, 2021
    Publication date: June 23, 2022
    Inventors: Stephen BLAKEMORE, Scott Richard DAIGLE
  • INHIBITORS OF EZH2 AND METHODS OF USE THEREOF
    Publication number: 20210052595
    Abstract: The disclosure provides a method of treating cancer in a subject in need thereof including administering to the subject a therapeutically-effective amount of an enhancer of a zeste homolog 2 (EZH2) inhibitor. In certain embodiments of this method, the subject has one or more mutations in one or more sequences encoding a gene listed in Tables 1-9, Tables 17-19, and/or FIGS. 19-22.
    Type: Application
    Filed: December 7, 2016
    Publication date: February 25, 2021
    Inventors: Stephen BLAKEMORE, Scott Richard DAIGLE