Patents by Inventor Stephen Boppart

Stephen Boppart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220397530
    Abstract: A photon peak event detection system accepts an analog output from a photon sensor, directly digitizes the analogy output and includes a graphics processing unit (GPU) programmed to conduct a photon peak event detection in real-time via a photon count program that analyzes the digitized photon sensor output in sampling periods each having at least three consecutive data points to determine a local maximum among the consecutive data points and compare the local maximum to one or more predetermined thresholds to determine whether or not a photon was received in each sampling period, the algorithm providing photon counts to a phasor analysis program in the GPU. The phasor analysis program calculates pixelwise fluorescence lifetime phasor data in real-time and sends the data to a central processing unit.
    Type: Application
    Filed: June 9, 2022
    Publication date: December 15, 2022
    Inventors: Stephen Boppart, Janet Sorrells, Rishyashring Raman Iyer
  • Publication number: 20070203404
    Abstract: A method of analyzing tissue includes inserting a radiation source into tissue, impinging radiation upon the tissue, obtaining a sample signal of the radiation that impinges upon the tissue, and determining a refractive index of the tissue from the sample signal. The method may also include determining at least one other optical property of the tissue. The method may provide for identifying tissue as part of a biopsy method. A device for analyzing tissue may include a low-coherence interferometer and a probe optically coupled to the interferometer, where the probe includes a radiation source.
    Type: Application
    Filed: January 31, 2007
    Publication date: August 30, 2007
    Inventors: Adam Zysk, Steven Adie, Matthew Leigh, Julian Armstrong, David Sampson, Stephen Boppart
  • Publication number: 20070184119
    Abstract: A microparticle contains a cross-linked protein shell, and a surface coating.
    Type: Application
    Filed: April 10, 2007
    Publication date: August 9, 2007
    Inventors: Kenneth Suslick, Farah Toublan, Stephen Boppart, Daniel Marks
  • Publication number: 20060285635
    Abstract: A method of forming an image of a sample includes performing SOCT on a sample. The sample may include a contrast agent, which may include an absorbing agent and/or a scattering agent. A method of forming an image of tissue may include selecting a contrast agent, delivering the contrast agent to the tissue, acquiring SOCT data from the tissue, and converting the SOCT data into an image. The contributions to the SOCT data of an absorbing agent and a scattering agent in a sample may be quantified separately.
    Type: Application
    Filed: April 14, 2006
    Publication date: December 21, 2006
    Inventors: Stephen Boppart, Chenyang Xu
  • Publication number: 20060192969
    Abstract: A method of examining a sample comprises exposing the sample to a pump pulse of electromagnetic radiation for a first period of time, exposing the sample to a stimulant pulse of electromagnetic radiation for a second period of time which overlaps in time with at least a portion of the first exposing, to produce a signal pulse of electromagnetic radiation for a third period of time, and interfering the signal pulse with a reference pulse of electromagnetic radiation, to determine which portions of the signal pulse were produced during the exposing of the sample to the stimulant pulse. The first and third periods of time are each greater than the second period of time.
    Type: Application
    Filed: February 28, 2005
    Publication date: August 31, 2006
    Inventors: Daniel Marks, Stephen Boppart
  • Publication number: 20060121123
    Abstract: A method of enhancing the contrast of an image of a sample, comprises forming an image of a mixture, by exposing the mixture to electromagnetic radiation. The mixture comprises the sample and microparticles. The enhancement is particularly suitable for optical coherence tomography.
    Type: Application
    Filed: June 17, 2003
    Publication date: June 8, 2006
    Inventors: Stephen Boppart, Daniel Marks, Kenneth Suslick, Farah Toublan
  • Publication number: 20050171433
    Abstract: A method of forming an image of a sample, comprising: forming an image of a mixture, by exposing the mixture to electromagnetic radiation; wherein the mixture comprises the sample and plasmon-resonant nanoparticles, and wherein the electromagnetic radiation is in the frequency range of infra-red to ultraviolet light.
    Type: Application
    Filed: January 8, 2004
    Publication date: August 4, 2005
    Inventors: Stephen Boppart, Alexander Wei
  • Publication number: 20050168735
    Abstract: A method of examining a sample, which includes: exposing a reference to a first set of electromagnetic radiation, to form a second set of electromagnetic radiation scattered from the reference; exposing a sample to a third set of electromagnetic radiation to form a fourth set of electromagnetic radiation scattered from the sample; and interfering the second set of electromagnetic radiation and the fourth set of electromagnetic radiation. The first set and the third set of electromagnetic radiation are generated from a source; at least a portion of the second set of electromagnetic radiation is of a frequency different from that of the first set of electromagnetic radiation; and at least a portion of the fourth set of electromagnetic radiation is of a frequency different from that of the third set of electromagnetic radiation.
    Type: Application
    Filed: November 19, 2003
    Publication date: August 4, 2005
    Inventors: Stephen Boppart, Daniel Marks