Abstract: A water purification system provides clean water for the consumption by livestock by using a continuously recirculating water loop. A circulating pump moves the water and a particle filter system is fluidically connected in series. An ozone purification system is fluidically connected in parallel to a portion of the continuously recirculating feedback monitored and control water loop. The ozone purification system is disposed downstream of the particle filter system in relation to the flow direction. A feeding station is connected in series with the continuously recirculating water loop disposed downstream of the ozone purification system in relation to the flow direction. An alkaline water apparatus is disposed upstream of the ozone purification unit, connected either before or in parallel to the ozone purification system. A decrystallization process apparatus is connected to continuously solubilize gases of CO2, N2, and inert gases with the flowing water.

Abstract: A water purification system provides clean water for the consumption by livestock by using a continuously recirculating water loop. A circulating pump moves the water within the water loop in a flow direction. A particle filter system is fluidically connected in series and removes dissolved solids or particulates within the water. An ozone purification system and/or with the addition of other antimicrobial or purification agents is fluidically connected in parallel to a portion of the continuously recirculating feedback monitored and control water loop. The ozone purification system is disposed downstream of the particle filter system in relation to the flow direction. A feeding station is connected in series with the continuously recirculating water loop disposed downstream of the ozone purification system in relation to the flow direction. An alkaline water apparatus is disposed upstream of the ozone purification unit, connected either before or in parallel to the ozone purification system.

Abstract: A method and system for managing a plurality of credit card transactions within an integrated accounting environment. Embodiments of the present disclosure enable integration between financial institutions, organizational accounting systems, and disparate user workflows to overcome deficiencies of the prior art. Specific embodiments enable tracking of credit card charges, credits, and payments directly within an accounts payable interface, enabling the ability to view activity on the credit card account record, register, and vendor record. Methods and systems are operable to establish a real-time data transfer protocol between a financial institution and an organizational accounting application to integrate transaction data in real-time, define vendor association for transactions, and create a real-time credit card register to drive decision making across disparate user roles.

Abstract: A water purification system provides clean water for the consumption by livestock by using a continuously recirculating water loop. A circulating pump moves the water within the water loop in a flow direction. A particle filter system is fluidically connected in series and removes dissolved solids or particulates within the water. An ozone purification system and/or with the addition of other antimicrobial or purification agents is fluidically connected in parallel to a portion of the continuously recirculating feedback monitored and control water loop. The ozone purification system is disposed downstream of the particle filter system in relation to the flow direction. A feeding station is connected in series with the continuously recirculating water loop disposed downstream of the ozone purification system in relation to the flow direction. An alkaline water apparatus is disposed upstream of the ozone purification unit, connected either before or in parallel to the ozone purification system.

Abstract: A water purification system provides clean water for the consumption by livestock by using a continuously recirculating water loop. Optionally, a circulating pump moves the water within the water loop in a flow direction. A water supply inlet is fluidically connected to the water loop to provide additional water. A particle filter system (or systems) is fluidically connected in series and removes dissolved solids or particulates within the water. An ozone purification system and/or with the addition of other antimicrobial or purification agents is fluidically connected in parallel to a portion of the continuously recirculating feedback monitored and control water loop. The ozone purification system is disposed downstream of the particle filter system and RO (or similar) system in relation to the flow direction. A feeding station is connected in series with the continuously recirculating water loop disposed downstream of the ozone purification system in relation to the flow direction.

Abstract: Provided herein is a multivalent Brucella vaccine expressing at least one heterologous M. tuberculosis antigen. The vaccines described herein serve as an environmentally safe bivalent vaccine for protection against Brucella and Mycobacterium infections simultaneously. In particular, a multivalent vaccine comprising a Brucella strain transformed with a vector that expresses at least one M. tuberculosis antigen, where the M. tuberculosis antigen(s) is codon optimized for the Brucella strain is provided. In some aspects, the Brucella strain is B. abortus strain RB51 leuB and the M. tuberculosis antigen is one or more of Ag85B, Rv2660c, and ESAT6.

Abstract: A method and system for managing a plurality of credit card transactions within an integrated accounting environment. Embodiments of the present disclosure enable integration between financial institutions, organizational accounting systems, and disparate user workflows to overcome deficiencies of the prior art. Specific embodiments enable tracking of credit card charges, credits, and payments directly within an accounts payable interface, enabling the ability to view activity on the credit card account record, register, and vendor record. Methods and systems are operable to establish a real-time data transfer protocol between a financial institution and an organizational accounting application to integrate transaction data in real-time, define vendor association for transactions, and create a real-time credit card register to drive decision making across disparate user roles.

Abstract: A water purification system provides clean water for the consumption by livestock by using a continuously recirculating water loop. Optionally, a circulating pump moves the water within the water loop in a flow direction. A water supply inlet is fluidically connected to the water loop to provide additional water. A particle filter system (or systems) is fluidically connected in series and removes dissolved solids or particulates within the water. An ozone purification system and/or with the addition of other antimicrobial or purification agents is fluidically connected in parallel to a portion of the continuously recirculating feedback monitored and control water loop. The ozone purification system is disposed downstream of the particle filter system and RO (or similar) system in relation to the flow direction. A feeding station is connected in series with the continuously recirculating water loop disposed downstream of the ozone purification system in relation to the flow direction.

Abstract: A method for the treatment of a condition which is characterized by CD 123-expressing cells in a patient comprises administering to the patient (i) an antibody or antibody fragment which binds selectively to IL-3R?(CD 123), and (ii) an immunostimulating complex which comprises saponin, a sterol and a phospholipid.

Abstract: A method for the treatment of a condition which is characterized by CD 123-expressing cells in a patient comprises administering to the patient (i) an antibody or antibody fragment which binds selectively to IL-3R?(CD 123), and (ii) an immunostimulating complex which comprises saponin, a sterol and a phospholipid.

Abstract: The present invention provides a method and composition for raising an immune response in an animal. The method comprising administering to the animal a composition comprising a carrier and an antigen bound to a targeting moiety. The targeting moiety binds to at least one receptor that is upregulated on lymphocytes that home to MAdCAM+ mucosal lymphoid tissues.

Abstract: The present invention provides a method and composition for raising an immune response in an animal. The method comprising administering to the animal a composition comprising a carrier and an antigen bound to a targeting moiety. The targeting moiety binds to at least one receptor that is upregulated on lymphocytes that home to MAdCAM+ mucosal lymphoid tissues.

Abstract: The present invention provides methods of enhancing the immune response to an immunogen and to compositions for use in these methods. In particular the present invention provides a DNA molecule for use in raising an immune response to an antigen. The DNA molecule includes a first sequence encoding a targeting molecule, a second sequence encoding the antigen or an epitope thereof, and optionally a third sequence encoding a polypeptide which promotes dimerization or multimerization of the product encoded by the DNA molecule.

Abstract: The present invention provides methods of enhancing the immune response to an immunogen and to compositions for use in these methods. In particular the present invention provides a DNA molecule for use in raising an immune response to an antigen. The DNA molecule includes a first sequence encoding a targeting molecule, a second sequence encoding the antigen or an epitope thereof, and optionally a third sequence encoding a polypeptide which promotes dimerization or multimerization of the product encoded by the DNA molecule.

Abstract: A recombinant, attenuated strain of Brucella suis with a deficiency in carboxyl-terminal protease (CtpA) activity can be used as a vaccine for the prevention or treatment of Brucellosis. Prior exposure to the Brucella species is identified by detecting a genetic sequence for carboxyl-terminal protease activity in a biological sample.

Abstract: A recombinant, attenuated strain of Brucella suis or Brucella melitensis with a deficiency in carboxyl-terminal protease activity or tail-specific protease activity can be used as a vaccine for the prevention or treatment of Brucellosis. Prior exposure to the Brucella species is identified by detecting a genetic sequence for carboxyl-terminal (i.e. tail-specific) protease activity in a biological sample.

Abstract: The present invention provides methods of enhancing the immune response to an immunogen and to compositions for use in these methods. In particular the present invention provides a DNA molecule for use in raising an immune response to an antigen. The DNA molecule includes a first sequence encoding a targeting molecule, a second sequence encoding the antigen or an epitope thereof, and optionally a third sequence encoding a polypeptide which promotes dimerization or multimerization of the product encoded by the DNA molecule.

Abstract: The present invention provides methods of enhancing the immune response to an immunogen and to compositions for use in these methods. In particular the present invention provides a DNA molecule for use in raising an immune response to an antigen. The DNA molecule includes a first sequence encoding a targeting molecule, a second sequence encoding the antigen or an epitope thereof, and optionally a third sequence encoding a polypeptide which promotes dimerisation or multimerisation of the product encoded by the DNA molecule.