Patents by Inventor Stephen Brough

Stephen Brough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel compound
    Publication number: 20050272750
    Abstract: A compound of formula (I) and pharmaceutically acceptable salts or solvates thereof for use in therapy.
    Type: Application
    Filed: September 16, 2003
    Publication date: December 8, 2005
    Applicant: AstraZeneca AB
    Inventors: Stephen Brough, Thomas McInally
  • Chemical compounds
    Patent number: 6958350
    Abstract: The invention provides a compound of formula (I): wherein R1, R2, R3, R4, R5, N, X and Y are as defined in the specification, processes, for their preparation, pharmaceutical compositions containing them, and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions.
    Type: Grant
    Filed: February 18, 2002
    Date of Patent: October 25, 2005
    Assignee: AstraZeneca AB
    Inventors: Stephen Brough, Thomas McInally, Matthew Perry, Brian Springthorpe
  • Compounds
    Patent number: 6946478
    Abstract: The invention provides compounds of general formula wherein R1, m, Q, T, n, R2, R3, V, W, X and R4 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: September 20, 2005
    Assignee: AstraZeneca AB
    Inventors: Andrew Baxter, Stephen Brough, Nicholas Kindon, Thomas McInally, Bryan Roberts, Stephen Thom
  • Novel substituted indoles
    Publication number: 20050165055
    Abstract: The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders.
    Type: Application
    Filed: May 27, 2003
    Publication date: July 28, 2005
    Inventors: Roger Bonnert, Stephen Brough, Tony Cook, Mark Dickinson, Rukhsana Rasul, Hitesh Sanganee, Simon Teague
  • Chemical compounds
    Publication number: 20040102483
    Abstract: The invention provides a compound of formula (I): wherein R1, R2, R3, R4, R5, N, X and Y are as defined in the specification, processes, for their preparation, pharmaceutical compositions containing them, and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions.
    Type: Application
    Filed: August 18, 2003
    Publication date: May 27, 2004
    Inventors: Stephen Brough, Thomas Mcinally, Matthew Perry, Brian Springthorpe
  • Novel compounds
    Publication number: 20030134840
    Abstract: The invention provides compounds of general formula 1
    Type: Application
    Filed: January 9, 2003
    Publication date: July 17, 2003
    Applicant: AstraZeneca AB, a Sweden corporation
    Inventors: Andrew Baxter, Stephen Brough, Nicholas Kindon, Thomas Mclnally, Bryan Roberts, Stephen Thom
  • Compounds
    Patent number: 6518286
    Abstract: The invention provides compounds of general formula (I) wherein: R1 represents optionally substituted, C1-C12 alkyl or optionally substituted 3- to 10-membered saturated or unsaturated ring system comprising up to two ring carbon atoms that form carbonyl groups and comprising up to 4 ring heteroatoms independently selected from nitrogen, oxygen and sulfur; m is 0-1; Q represents OCH2, C1-C4 alkylene or C2-C4 alkenylene; T represents C(O)NH, or when m is 0, T may additionally represent a bond or NH, or when m is 1 and Q represents C1-C4 alkylene, T may additionally represent NH; n is 1-4; each R2 and R3 independently represents H or C1-C4 alkyl; V represents N, and W represents N or CH; X represents O, C(O), CH(OH), SO2, NH or N(C1-C6 alkyl), provided that when W represents N, then X represents either C(O) or SO2 and when W represents CH, then X is other than SO2; R4 represents optionally substituted phenyl; R5 and R6 each independently represent H, C1-C6 alkyl or hydroxyC1-C6 alkyl, or R5 and R6 together with
    Type: Grant
    Filed: June 1, 2000
    Date of Patent: February 11, 2003
    Assignee: AstraZeneca AB
    Inventors: Andrew Baxter, Stephen Brough, Nicholas Kindon, Thomas McInally, Bryan Roberts, Stephen Thom
  • Novel Compounds
    Publication number: 20020107252
    Abstract: The invention relates to heteroaromatic carboxamides of formula (I), 1
    Type: Application
    Filed: February 5, 2002
    Publication date: August 8, 2002
    Inventors: Andrew Baxter, Stephen Brough, Alan Faull, Craig Johnstone, Thomas McInally
  • Adamantane derivatives
    Patent number: 6242470
    Abstract: The invention provides adamantane derivatives, a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: June 5, 2001
    Assignee: AstraZeneca AB
    Inventors: Andrew Baxter, Stephen Brough, Thomas McInally, Michael Mortimore