Patents by Inventor Stephen Bryan

Stephen Bryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030203945
    Abstract: This invention relates to novel heterocyclic derivatives of the formula (VII), (VIII) or (IX) 1
    Type: Application
    Filed: May 5, 2003
    Publication date: October 30, 2003
    Inventors: David Clive Blakemore, Justin Stephen Bryans, Sophie Caroline Williams
  • Patent number: 6635673
    Abstract: The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.
    Type: Grant
    Filed: February 8, 2000
    Date of Patent: October 21, 2003
    Assignee: Warner-Lambert Company
    Inventors: Justin Stephen Bryans, David Christopher Horwell, Andrew John Thorpe, David Juergen Wustrow, Po-Wai Yuen
  • Publication number: 20030187296
    Abstract: A method is provided for making an enantiomerically pure of the formula: in which R and R′ represent C1?C10 alkyl, C2?C10 alkenyl or C3?C10 cycloalkyl and the wedges signify (S)- or (R)-stereochemistry, the substituents in compound (II) being trans. Conjugate addition is carried out between an organometallic nucleophile that provides a group R as defined above and (R)-4-acetoxycyclopent-2-en-1-one, (S)-4-acetoxycyclopent-2-en-1-one or a similar compound in which acetoxy is replaced by another leaving group to give, e.g.
    Type: Application
    Filed: February 5, 2003
    Publication date: October 2, 2003
    Inventors: David Clive Blakemore, Justin Stephen Bryans
  • Publication number: 20030181523
    Abstract: The instant invention is a series of novel mono- and disubstituted 3-propyl gamma aminobutyric acids of Formula I 1
    Type: Application
    Filed: December 20, 2002
    Publication date: September 25, 2003
    Inventors: Thomas Richard Belliotti, Justin Stephen Bryans, Ihoezo Victor Ekhato, Augustine Tobi Osuma, Robert Michael Schelkun, Jacob Bradley Schwarz, Andrew John Thorpe, Lawrence David Wise, David Juergen Wustrow, Po-Wai Yuen
  • Publication number: 20030144214
    Abstract: GABA-related pro-drugs of the formula (III) are provided that when administered to humans or other mammals provide an increased duration of active compound in the plasma compared to compounds of corresponding structure in which labile groups are not present.
    Type: Application
    Filed: November 21, 2002
    Publication date: July 31, 2003
    Inventors: David Clive Blakemore, Justin Stephen Bryans, Sophie Caroline Williams
  • Patent number: 6596900
    Abstract: The compounds of the instant invention are bicyclic or tricyclic amino acids useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis, neuropathological disorders, sleep disorders, visceral pain disorders, and gastrointestinal disorders. Processes for the preparation of the final products and intermediates useful in the process are included. Pharmaceutical compositions containing one or more of the compounds are also included.
    Type: Grant
    Filed: April 16, 2002
    Date of Patent: July 22, 2003
    Assignee: Pfizer Inc
    Inventors: David Clive Blakemore, Justin Stephen Bryans, Sophie Caroline Williams
  • Publication number: 20030119858
    Abstract: Novel substituted amino acids of formula 1
    Type: Application
    Filed: October 22, 2002
    Publication date: June 26, 2003
    Inventors: Justin Stephen Bryans, David Christopher Horwell, Jean-Marie Receveur
  • Publication number: 20030083520
    Abstract: The invention relates to a process for preparing (1&agr;,3&agr;,5&agr;)(3-aminomethyl-bicyclo[3.2.0]hept-3-yl)-acetic acid, or an acid addition salt thereof.
    Type: Application
    Filed: May 2, 2002
    Publication date: May 1, 2003
    Applicant: Pfizer Inc.
    Inventors: David Clive Blakemore, Justin Stephen Bryans
  • Publication number: 20030078300
    Abstract: The compounds of the instant invention are bicyclic or tricyclic amino acids useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis, neuropathological disorders, sleep disorders, visceral pain disorders, and gastrointestinal disorders. Processes for the preparation of the final products and intermediates useful in the process are included. Pharmaceutical compositions containing one or more of the compounds are also included.
    Type: Application
    Filed: April 16, 2002
    Publication date: April 24, 2003
    Applicant: Pfizer Inc.
    Inventors: David Clive Blakemore, Justin Stephen Bryans, Sophie Caroline Williams
  • Publication number: 20030069438
    Abstract: 1
    Type: Application
    Filed: June 6, 2002
    Publication date: April 10, 2003
    Inventors: Justin Stephen Bryans, David Clive Blakemore, Sophie Caroline Williams
  • Patent number: 6545022
    Abstract: Novel amines of formulas 1D and 1E are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, inflammatory diseases, and gastrointestinal disorders, especially IBS. Processes for the preparation and intermediates useful in the preparation are also disclosed.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: April 8, 2003
    Assignee: Pfizer Inc.
    Inventors: Justin Stephen Bryans, David Christopher Horwell, Clare Octavia Kneen, David Juergen Wustrow
  • Patent number: 6521650
    Abstract: Novel gamma aminobutyric acids of formula (I) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, inflammation, and gastrointestinal damage. Processes for the preparation and intermediates useful in the preparation are also disclosed.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: February 18, 2003
    Assignee: Pfizer, Inc.
    Inventors: Thomas Richard Belliotti, Justin Stephen Bryans, Thomas Capiris, David Christopher Horwell, Clare Octavia Kneen, David Juergen Wustrow
  • Patent number: 6518289
    Abstract: Novel amines of formulas (1), (1C), (1F), (1G) and (1H) or a pharmaceutical acceptable salt thereof wherein n is an integer of from 0 to 2; m is an integer of from 0 to 3; R is sulfonamide, amide, phosphonic acid, heterocycle, sulfonic acid, or hydroxamic acid; A′ is a bridged ring selected from (1), (2), (3), (4), (5) wherein is the point of attachment; Z1 to Z4 are each independently selected from hydrogen and methyl; o is an integer of from 1 to 4; and p is an integer of from 0 to 2. In formula (1) above R cannot be sulfonic acid when m is 2 and n is 1 are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, especially irritable bowel syndrome.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: February 11, 2003
    Assignee: Pfizer, Inc.
    Inventors: Justin Stephen Bryans, Thomas Capiris, David Christopher Horwell, Clare Octavia Kneen, David Juergen Wustrow
  • Patent number: 6489352
    Abstract: Novel substituted amino acids of formula are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, and neuropathological disorders. Processes for the preparation and intermediates useful in the preparation are also disclosed.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: December 3, 2002
    Assignee: Warner-Lambert Company
    Inventors: Justin Stephen Bryans, David Christopher Horwell, Jean-Marie Receveur
  • Patent number: 6465689
    Abstract: This invention is novel processes for the stereoselective preparation of gabapentin analogues.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: October 15, 2002
    Assignee: Warner-Lambert Company
    Inventors: Justin Stephen Bryans, Andrew Ian Morrell
  • Publication number: 20020099092
    Abstract: GABA-related pro-drugs of the formula (III) are provided that when administered to humans or other mammals provide an increased duration of active compound in the plasma compared to compounds of corresponding structure in which labile groups are not present.
    Type: Application
    Filed: August 1, 2001
    Publication date: July 25, 2002
    Inventors: David Clive Blakemore, Justin Stephen Bryans, Sophie Caroline Williams
  • Publication number: 20020077342
    Abstract: This invention relates to novel heterocyclic derivatives of the formula (VII), (VIII) or (IX) 1
    Type: Application
    Filed: October 26, 2001
    Publication date: June 20, 2002
    Inventors: David Clive Blakemore, Justin Stephen Bryans, Sophie Caroline Williams
  • Publication number: 20020019540
    Abstract: Novel substituted amino acids of formula 1
    Type: Application
    Filed: August 8, 2001
    Publication date: February 14, 2002
    Inventors: Justin Stephen Bryans, David Christopher Horwell, Jean-Marie Receveur
  • Patent number: 6316638
    Abstract: Novel substituted amino acids of formula are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, and neuropathological disorders. Processes for the preparation and intermediates useful in the preparation are also disclosed.
    Type: Grant
    Filed: August 16, 2000
    Date of Patent: November 13, 2001
    Assignee: Warner-Lambert Company
    Inventors: Justin Stephen Bryans, David Christopher Horwell, Jean-Marie Receveur
  • Patent number: 6309164
    Abstract: The invention provides a refuse and recyclable materials collection system which includes a self-dumping bin, a hauling unit with a tailgate and an opening top, side or both, a compacting ram that empties the hopper into the body, compacts and ejects the collected materials. The collection vehicle is placed into a loading position, which can be on either side of the vehicle. For collection of two different types of recyclable materials the collection vehicle can be equipped with two receiving doors, hoppers, rams, compacting chambers and tailgates. The self-dumping bin receives power by connecting hydraulic lines from the collection vehicle. The self-dumping bin is then raised to the dumping position by a lifting mechanism. The receiving door opens to form a chute for receiving the materials from the self-dumping bin. A baffle on each of the receiving doors forms a trap to prevent spillage. The bin has a tapered “lip” that funnels the material into the hopper of the hauling unit.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: October 30, 2001
    Assignee: Hol-Mac Corporation
    Inventors: Jamie Val Holder, Stephen Bryan Adkins, Robert William Fallon