Patents by Inventor Stephen Byers

Stephen Byers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosing and evaluating cancer
    Publication number: 20040248220
    Abstract: Methods for diagnosing cancer, such as prostate, ovarian or breast cancer, as well as leukemia, are provided. Such methods may employ binding agents, such as antibodies or CAR sequences of OB-cadherin or N-cadherin, that specifically bind to OB-cadherin or N-cadherin, or polynucleotides that hybridize to a polynucleotide encoding OB-cadherin or N-cadherin. Also provided are methods for monitoring the progression of a cancer and to evaluate the metastatic potential of a cancer.
    Type: Application
    Filed: January 16, 2004
    Publication date: December 9, 2004
    Applicant: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, James Matthew Symonds, Stephen Byers, Barbara J. Gour
  • Methods for diagnosing and evaluating cancer
    Publication number: 20040248219
    Abstract: Methods for diagnosing cancer, such as prostate, ovarian or breast cancer, as well as leukemia, are provided. Such methods may employ binding agents, such as antibodies or CAR sequences of OB-cadherin or N-cadherin, that specifically bind to OB-cadherin or N-cadherin, or polynucleotides that hybridize to a polynucleotide encoding OB-cadherin or N-cadherin. Also provided are methods for monitoring the progression of a cancer and to evaluate the metastatic potential of a cancer.
    Type: Application
    Filed: January 16, 2004
    Publication date: December 9, 2004
    Applicant: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, James Matthew Symonds, Stephen Byers, Barbara J. Gour
  • Thermal control of a DUT using a thermal control substrate
    Patent number: 6825681
    Abstract: A solid state thermal control device contains a substrate and a plurality of solid state thermal elements on the substrate. The thermal elements are adapted to provide thermal control to a device under test (DUT). Each solid state thermal element contains at least one solid state heater and an active control circuit adapted to control a thermal output of the heater. Optionally, the each thermal element may also include a solid state temperature sensor.
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: November 30, 2004
    Assignee: Delta Design, Inc.
    Inventors: Jan Feder, Rick Beyerle, Stephen Byers, Thomas Jones
  • Compounds and methods for stimulating beta-catenin mediated gene expression and differentiation
    Publication number: 20040142854
    Abstract: Modulating agents for inhibiting degradation of cytoplasmic &bgr;-catenin are provided. The modulating agents comprise one or more of: (1) the peptide sequence SYLDS(PO4)GIHS(PO4)G (SEQ ID NO:1) or (2) a peptide analogue or peptidomimetic thereof. Methods for using such modulating agents for stimulating &bgr;-catenin mediated gene expression and cellular differentiation are provided.
    Type: Application
    Filed: October 21, 2003
    Publication date: July 22, 2004
    Applicant: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, Stephen Byers, Barbara J. Gour
  • Compounds and methods for stimulating &bgr;-catenin mediated gene expression and differentiation
    Patent number: 6706685
    Abstract: Modulating agents for inhibiting degradation of cytoplasmic &bgr;-catenin are provided. The modulating agents comprise one or more of: (1) the peptide sequence SYLDS(PO4)GIHS(PO4)G (SEQ ID NO:1) or (2) a peptide analogue or peptidomimetic thereof. Methods for using such modulating agents for stimulating &bgr;-catenin mediated gene expression and cellular differentiation are provided.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: March 16, 2004
    Assignee: Adherex Technologies Inc.
    Inventors: Orest W. Blaschuk, Stephen Byers, Barbara J. Gour
  • Methods for diagnosing and evaluating cancer
    Patent number: 6682901
    Abstract: Methods for diagnosing cancer, such as prostate, ovarian or breast cancer, as well as leukemia, are provided. Such methods may employ binding agents, such as antibodies or CAR sequences of OB-cadherin or N-cadherin, that specifically bind to OB-cadherin or N-cadherin, or polynucleotides that hybridize to a polynucleotide encoding OB-cadherin or N-cadherin. Also provided are methods for monitoring the progression of a cancer and to evaluate the metastatic potential of a cancer.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: January 27, 2004
    Assignee: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, James Matthew Symonds, Stephen Byers, Barbara J. Gour
  • Thermal control of a DUT using a thermal contro substrate
    Publication number: 20040012404
    Abstract: A solid state thermal control device contains a substrate and a plurality of solid state thermal elements on the substrate. The thermal elements are adapted to provide thermal control to a device under test (DUT). Each solid state thermal element contains at least one solid state heater and an active control circuit adapted to control a thermal output of the heater. Optionally, the each thermal element may also include a solid state temperature sensor.
    Type: Application
    Filed: July 19, 2002
    Publication date: January 22, 2004
    Applicant: Delta Design, Inc.
    Inventors: Jan Feder, Rick Beyerle, Stephen Byers, Thomas Jones
  • Methods for diagnosing and evaluating cancer
    Patent number: 6680175
    Abstract: Methods for diagnosing cancer, such as prostate, ovarian or breast cancer, as well as leukemia, are provided. Such methods may employ binding agents, such as antibodies or CAR sequences of OB-cadherin or N-cadherin, that specifically bind to OB-cadherin or N-cadherin, or polynucleotides that hybridize to a polynucleotide encoding OB-cadherin or N-cadherin. Also provided are methods for monitoring the progression of a cancer and to evaluate the metastatic potential of a cancer.
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: January 20, 2004
    Assignee: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, James Matthew Symonds, Stephen Byers, Barbara J. Gour
  • Methods for treating cancer by modulating &bgr;-catenin mediated gene expression
    Patent number: 6677116
    Abstract: Modulating agents for inhibiting &bgr;-catenin mediated gene expression are provided. The modulating agents comprise one or more of: (1) the peptide sequence LXXLL (SEQ ID NO:1); or (2) a peptide analogue or peptidomimetic thereof. Methods for using such modulating agents for modulating &bgr;-catenin mediated gene expression and cellular differentiation in a variety of contexts (e.g., for modulating hair growth or treating cancer or Alzheimer's disease) are provided.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: January 13, 2004
    Assignee: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, Stephen Byers, Barbara J. Gour
  • Compounds and methods for inhibiting cancer metastasis
    Patent number: 6593297
    Abstract: Agents for inhibiting cancer metastasis are provided. The methods comprise administering to a patient an antimetastatic agent that comprises one or more of: (a) a peptide sequence that is at least 50% identical to an OB-cadherin CAR sequence; (b) a non-peptide mimetic of an OB-cadherin CAR sequence; (c) a substance, such as an antibody or antigen-binding fragment thereof, that specifically binds an OB-cadherin CAR sequence; and/or (d) a polynucleotide encoding a polypeptide that comprises an OB-cadherin CAR sequence or analogue thereof.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: July 15, 2003
    Assignee: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, James Matthew Symonds, Stephen Byers, Barbara J. Gour
  • Compounds and methods for inhibiting cancer metastasis
    Publication number: 20030096746
    Abstract: Agents for inhibiting cancer metastasis are provided.
    Type: Application
    Filed: May 7, 2002
    Publication date: May 22, 2003
    Applicant: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, James Matthew Symonds, Stephen Byers, Barbara J. Gour
  • COMPOUNDS AND METHODS FOR INHIBITING CANCER METASTASIS
    Publication number: 20020169106
    Abstract: Agents for inhibiting cancer metastasis are provided. The methods comprise administering to a patient an antimetastatic agent that comprises one or more of: (a) a peptide sequence that is at least 50% identical to an OB-cadherin CAR sequence; (b) a non-peptide mimetic of an OB-cadherin CAR sequence; (c) a substance, such as an antibody or antigen-binding fragment thereof, that specifically binds an OB-cadherin CAR sequence; and/or (d) a polynucleotide encoding a polypeptide that comprises an OB-cadherin CAR sequence or analogue thereof.
    Type: Application
    Filed: March 8, 1999
    Publication date: November 14, 2002
    Inventors: OREST W. BLASCHUK, STEPHEN BYERS, BARBARA J. GOUR, JAMES MATTHEW SYMONDS
  • METHODS FOR DIAGNOSING AND EVALUATING CANCER
    Publication number: 20020146687
    Abstract: Methods for diagnosing cancer, such as prostate, ovarian or breast cancer, as well as leukemia, are provided. Such methods may employ binding agents, such as antibodies or CAR sequences of OB-cadherin or N-cadherin, that specifically bind to OB-cadherin or N-cadherin, or polynucleotides that hybridize to a polynucleotide encoding OB-cadherin or N-cadherin. Also provided are methods for monitoring the progression of a cancer and to evaluate the metastatic potential of a cancer.
    Type: Application
    Filed: May 5, 1999
    Publication date: October 10, 2002
    Inventors: OREST W. BLASCHUK, JAMES MATTHEW SYMONDS, STEPHEN BYERS, BARBARA J. GOUR
  • METHODS FOR DIAGNOSING AND EVALUATING CANCER
    Publication number: 20020123044
    Abstract: Methods for diagnosing cancer, such as prostate, ovarian or breast cancer, as well as leukemia, are provided. Such methods may employ binding agents, such as antibodies or CAR sequences of OB-cadherin or N-cadherin, that specifically bind to OB-cadherin or N-cadherin, or polynucleotides that hybridize to a polynucleotide encoding OB-cadherin or N-cadherin. Also provided are methods for monitoring the progression of a cancer and to evaluate the metastatic potential of a cancer.
    Type: Application
    Filed: January 20, 1999
    Publication date: September 5, 2002
    Inventors: OREST W. BLASCHUK, JAMES MATTHEWS SYMONDS, STEPHEN BYERS, BARBARA J. GOUR
  • Compounds and methods for inhibiting cancer metastasis
    Patent number: 6433149
    Abstract: Agents for inhibiting cancer metastasis are provided. The methods comprise administering to a patient an antimetastatic agent that comprises one or more of: (a) a peptide sequence that is at least 50% identical to an OB-cadherin CAR sequence; (b) a non-peptide mimetic of an OB-cadherin CAR sequence; (c) a substance, such as an antibody or antigen-binding fragment thereof, that specifically binds an OB-cadherin CAR sequence; and/or (d) a polynucleotide encoding a polypeptide that comprises an OB-cadherin CAR sequence or analogue thereof.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: August 13, 2002
    Assignee: Adherex Technologies, Inc.
    Inventors: Orest W. Blaschuk, James Matthew Symonds, Stephen Byers, Barbara J. Gour
  • Compounds and methods for modulating &bgr;-catenin mediated gene expression
    Patent number: 6303576
    Abstract: Modulating agents for inhibiting &bgr;-catenin mediated gene expression are provided. The modulating agents comprise one or more of: (1) the peptide sequence LXXLL (SEQ ID NO:1); or (2) a peptide analogue or peptidomimetic thereof. Methods for using such modulating agents for modulating &bgr;-catenin mediated gene expression and cellular differentiation in a variety of contexts (e.g., for modulating hair growth or treating cancer or Alzheimer's disease) are provided.
    Type: Grant
    Filed: April 21, 1999
    Date of Patent: October 16, 2001
    Assignee: Adherex Technologies Inc.
    Inventors: Orest W. Blaschuk, Stephen Byers, Barbara J. Gour