Patents by Inventor Stephen C. Benz

Stephen C. Benz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patient-specific cellular pathway activity inference computer system
    Patent number: 11355218
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: June 7, 2022
    Assignee: THF REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • Pathway analysis computing system and method
    Patent number: 11043282
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: June 22, 2021
    Assignee: THE REGENTS OF THE UNVIERSITY OF CALIFORNIA
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • Pathway recognition algorithm using data integration on genomic models (paradigm)
    Patent number: 10991448
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: April 27, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • Method for treating an individual patient
    Patent number: 10916329
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: February 9, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussier
  • Method of providing a treatment to a subject based on a dynamic pathway map
    Patent number: 10770169
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: September 8, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM)
    Publication number: 20190341123
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Application
    Filed: August 2, 2017
    Publication date: November 7, 2019
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • Method of generating a dynamic pathway map
    Patent number: 10192641
    Abstract: A method of generating a dynamic pathway map (DPM) is provided. The method includes accessing a model database that stores a probabilistic pathway model that comprises a plurality of pathway elements, a first number of the plurality of pathway elements are cross-correlated and assigned an influence level for at least one pathway on the basis of known attributes, a second number of the plurality of pathway elements are cross-correlated and assigned an influence level for at least one pathway on the basis of assumed attributes. The method includes measuring a patient sample to identify measured attributes of the patient sample and using a plurality of the measured attributes of the patient sample, via an analysis engine, to modify the probabilistic pathway model to obtain the DPM, wherein the DPM has reference pathway activity information for a particular pathway, the reference pathway indicating deviations from the probabilistic pathway model.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: January 29, 2019
    Assignee: The Regents of the University of California
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM)
    Publication number: 20180046751
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 15, 2018
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM)
    Publication number: 20180046752
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 15, 2018
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM)
    Publication number: 20180011966
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Application
    Filed: August 2, 2017
    Publication date: January 11, 2018
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • PATHWAY RECOGNITION ALGORITHM USING DATA INTEGRATION ON GENOMIC MODELS (PARADIGM)
    Publication number: 20150142465
    Abstract: A patient sample specific dynamic pathway map is constructed on the basis of measured patient data and a probabilistic pathway model that is based on attributes for pathway elements, wherein some attributes for pathway elements are known a priori, where other attributes for the pathway elements are assumed, and where the pathway elements are cross-correlated and assigned an influence level for at least one pathway. Preferred dynamic pathway maps provide context of the measured patient data with respect to a selected reference pathway activity.
    Type: Application
    Filed: December 19, 2014
    Publication date: May 21, 2015
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • Pathway recognition algorithm using data integration on genomic models (PAGADIGM)
    Publication number: 20120158391
    Abstract: A patient sample specific dynamic pathway map is constructed on the basis of measured patient data and a probabilistic pathway model that is based on attributes for pathway elements, wherein some attributes for pathway elements are known a priori, where other attributes for the pathway elements are assumed, and where the pathway elements are cross-correlated and assigned an influence level for at least one pathway. Preferred dynamic pathway maps provide context of the measured patient data with respect to a selected reference pathway activity.
    Type: Application
    Filed: October 26, 2011
    Publication date: June 21, 2012
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler
  • Pathway recognition algorithm using data integration on genomic models (PARADIGM)
    Publication number: 20120041683
    Abstract: The present invention relates to methods for evaluating the probability that a patient's diagnosis may be treated with a particular clinical regimen or therapy.
    Type: Application
    Filed: April 29, 2011
    Publication date: February 16, 2012
    Inventors: Charles J. Vaske, Stephen C. Benz, Joshua M. Stuart, David Haussler