Abstract: Described herein are methods for producing and identifying characteristic (“crescent shaped”) regions indicative of an atherectomy plaque within a vessel, and systems and devices adapted to take advantage of this characteristic region.

Abstract: The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tis -sue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.

Abstract: The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tissue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.

Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body.

Abstract: Described herein are methods for producing and identifying characteristic (“crescent shaped”) regions indicative of an atherectomy plaque within a vessel, and systems and devices adapted to take advantage of this characteristic region.

Abstract: The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tissue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.

Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body and an imaging shaft connected to the imaging element and extending within the catheter body. The cutter and the imaging element are mechanically isolated, and the drive shaft is configured to be axially translated relative to the imaging shaft and the catheter body.

Abstract: The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tissue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.

Abstract: Image-based fire detection methods are provided which include analyzing a field of view based on a plurality of images, determining if changes occur, and analyzing whether any such changes are due to smoke-like material. Changes due to large objects are ruled out, and drift in the scene or shaking of the image collection device is accounted for by the method. The methods employ representing images of the field of view with quantifiable values and comparing to thresholds established for each event, and activating an alarm if changes due to smoke-like material are detected. The fire detection methods may also include monitoring a field of view for changes, and only performing the analysis on the images if changes are detected. The monitoring and validating stages of the methods include collecting images at different sampling rates for different amounts of information.

Abstract: A fire detection device is provided that has a camera that captures a reference image and a measured image. A processor compares intensity of the measured image to intensity of the reference image and uses this comparison to determine if an alarm is generated to indicate the presence of fire. The intensity of the measured image may be the total number of photons of the measured image, and the intensity of the reference image may be the total number of photons of the reference image. In other arrangements, the intensity may be measured between individual corresponding pixels of the reference and measured images.

Abstract: Image-based fire detection methods are provided which include analyzing a field of view based on a plurality of images, determining if changes occur, and analyzing whether any such changes are due to smoke-like material. Changes due to large objects are ruled out, and drift in the scene or shaking of the image collection device is accounted for by the method. The methods employ representing images of the field of view with quantifiable values and comparing to thresholds established for each event, and activating an alarm if changes due to smoke-like material are detected. The fire detection methods may also include monitoring a field of view for changes, and only performing the analysis on the images if changes are detected. The monitoring and validating stages of the methods include collecting images at different sampling rates for different amounts of information.

Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body and an imaging shaft connected to the imaging element and extending within the catheter body. The cutter and the imaging element are mechanically isolated, and the drive shaft is configured to be axially translated relative to the imaging shaft and the catheter body.

Abstract: A health monitoring toilet system collects urine in a toilet system which may resemble a traditional water toilet. The toilet system may include a urine capture basin for collecting urine as a user urinates as with a traditional toilet. The urine capture basin may include a urine entry aperture which is an orifice leading into a urine sample cell. A fiber optic spectrometer may analyze the urine in the urine sample cell to collect relevant health data. The system may include a controller which may store and analyze spectral data and compile longitudinal data over time. The system may be in connection with other such systems to compare the analysis of a user's urine with those of other users stored in other such health monitoring toilet systems.

Abstract: The present invention relates to a urine specimen capture device comprising a narrow slit disposed on a surface exposed to urine that retains a portion of the urine specimen.

Abstract: The present invention relates to a urine specimen capture device comprising a capture bowl to capture a urine specimen, a mounting frame connected to the capture bowl to support the capture bowl within a toilet bowl and one or more flush water capture flange for capturing flush water emitted from a toilet bowl rim during a toilet flush cycle and diverting the flush water to the capture bowl to rinse the capture bowl of the urine specimen.

Abstract: The urine specimen capture device includes a capture bowl for collecting a urine specimen, a mounting frame for supporting the capture bowl within a toilet bowl, and an analytic device connected to the capture bowl to analyze a property of the urine specimen in the capture bowl. The capture bowl includes a capture flange for capturing flush water discharged from a toilet bowl.

Abstract: The present invention relates to a urine specimen capture device comprising a capture bowl for collecting a urine specimen, a mounting frame for supporting the capture bowl within a toilet bowl, and an analytic device connected to the capture bowl to analyze a property of the urine specimen in the capture bowl.

Abstract: The present invention relates to a urine specimen capture device comprising a capture bowl for collecting a urine specimen, a mounting frame for supporting the capture bowl within a toilet bowl, and an analytic device connected to the capture bowl to analyze a property of the urine specimen in the capture bowl. The capture bowl includes a capture flange for capturing flush water discharged from a toilet bowl.

Abstract: Image-based fire detection methods are provided which include analyzing a field of view based on a plurality of images, determining if changes occur, and analyzing whether any such changes are due to smoke-like material. Changes due to large objects are ruled out, and drift in the scene or shaking of the image collection device is accounted for by the method. The methods employ representing images of the field of view with quantifiable values and comparing to thresholds established for each event, and activating an alarm if changes due to smoke-like material are detected. The fire detection methods may also include monitoring a field of view for changes, and only performing the analysis on the images if changes are detected. The monitoring and validating stages of the methods include collecting images at different sampling rates for different amounts of information.

Abstract: A fire detection device is provided that has a camera that captures a reference image and a measured image. A processor compares intensity of the measured image to intensity of the reference image and uses this comparison to determine if an alarm is generated to indicate the presence of fire. The intensity of the measured image may be the total number of photons of the measured image, and the intensity of the reference image may be the total number of photons of the reference image. In other arrangements, the intensity may be measured between individual corresponding pixels of the reference and measured images.