Patents by Inventor Stephen C. Ransom

Stephen C. Ransom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition and method for maintaining non-enveloped viral vectors
    Publication number: 20030153065
    Abstract: The invention provides a composition and a method for preserving a non-enveloped viral vector. The composition comprises (a) trehalose, (b) a divalent metal salt, a cationic polymer, or a combination thereof, (c) a multiplicity of non-enveloped viral vector particles, and (d) a liquid carrier. Non-enveloped virus particles are stable in the composition in a liquid form, at elevated temperatures, for a sustained period of time.
    Type: Application
    Filed: January 14, 2002
    Publication date: August 14, 2003
    Applicant: GenVec, Inc.
    Inventors: Imre Kovesdi, Stephen C. Ransom
  • Method and composition for preserving viruses
    Patent number: 6514943
    Abstract: The present invention provides a method and a composition for preserving a virus. The virus is placed in a liquid carrier with a stabilizing agent selected from the group consisting of polysorbate 80, L-arginine, polyvinylpyrrolidone, trehalose, and combinations thereof. The liquid composition can be maintained at a temperature above 0° C. for a significant period of time while maintaining a satisfactory degree of viral activity.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: February 4, 2003
    Assignee: GenVec, Inc.
    Inventors: Imre Kovesdi, Stephen C. Ransom
  • Method and composition for preserving viruses
    Publication number: 20020019041
    Abstract: The present invention provides a method and a composition for preserving a virus. The virus is placed in a liquid carrier with a stabilizing agent selected from the group consisting of polysorbate 80, L-arginine, polyvinylpyrrolidone, trehalose, and combinations thereof. The liquid composition can be maintained at a temperature above 0° C. for a significant period of time while maintaining a satisfactory degree of viral activity.
    Type: Application
    Filed: May 31, 2001
    Publication date: February 14, 2002
    Applicant: GenVec, Inc.
    Inventors: Imre Kovesdi, Stephen C. Ransom
  • Methods and compositions for preserving adenoviral vectors
    Patent number: 6225289
    Abstract: The present invention provides a method and composition for preserving an adenoviral vector. Both the method and composition involve the use of an adenoviral gene transfer vector, a pharmaceutically acceptable liquid carrier, and a stabilizing agent, which enables the adenoviral vector to be maintained at a temperature above 0° C. for at least 7 days.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: May 1, 2001
    Assignee: GenVec, Inc.
    Inventors: Imre Kovesdi, Stephen C. Ransom