Patents by Inventor Stephen C. Wardlaw

Stephen C. Wardlaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200278341
    Abstract: A method and device for analyzing a hematologic sample centrifuged within a capillary tube is provided. The device includes a tube holder, a sample imaging device, a processor, and a sample data display. The sample imaging device is operable to create a digital image of the sample within a region of the tube. The region is defined by substantially all of the radial width and axial length of the sample residing within the internal cavity of the tube in the region where the float resides after centrifugation. The sample imaging device is operable to produce signals representative of the image. The processor is adapted to produce information relating to bands of interest within the image based on the signals from the sample imaging device. The sample data display is adapted to display the results therefrom and/or a digital image of the sample within the region.
    Type: Application
    Filed: March 9, 2020
    Publication date: September 3, 2020
    Inventors: Joshua D. Levine, Robert A. Levine, Stephen C. Wardlaw, Craig Stout, David A. Clipper
  • Patent number: 10677711
    Abstract: An apparatus and a method for identifying at least one type of white blood cell (WBC) within a whole blood sample is provided. The method includes: adding at least one colorant to the sample; providing at least one fluorescent excitation light and at least one transmission light; receiving both light fluorescing from and transmitted through the sample and producing signals representative thereof; creating at least one image of the sample using the signals; identifying WBCs within the sample image; quantitatively analyzing at least some of the identified WBCs within the image, including determining one or more quantitative values; and identifying at least one type of WBC from the identified WBCs using the quantitative values.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: June 9, 2020
    Assignee: Abbott Point of Care, Inc.
    Inventors: David Herzog, Zhizhou Wang, Stephen C. Wardlaw, Min Xie
  • Patent number: 10627390
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: April 21, 2020
    Assignee: Abbott Point of Care, Inc.
    Inventors: Min Xie, Stephen C. Wardlaw
  • Patent number: 10585084
    Abstract: A method and device for analyzing a hematologic sample centrifuged within a capillary tube is provided. The device includes a tube holder, a sample imaging device, a processor, and a sample data display. The sample imaging device is operable to create a digital image of the sample within a region of the tube. The region is defined by substantially all of the radial width and axial length of the sample residing within the internal cavity of the tube in the region where the float resides after centrifugation. The sample imaging device is operable to produce signals representative of the image. The processor is adapted to produce information relating to bands of interest within the image based on the signals from the sample imaging device. The sample data display is adapted to display the results therefrom and/or a digital image of the sample within the region.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: March 10, 2020
    Inventors: Joshua D. Levine, Robert A. Levine, Stephen C. Wardlaw, Craig Stout, David A. Clipper
  • Patent number: 10578602
    Abstract: An apparatus for analyzing biologic fluid is provided that includes a first planar member, a second planar member, and at least three separators. At least one of planar members is transparent. The separators are disposed between the members, and separate the members to form a chamber having a height. At least one of the members or separators is sufficiently flexible to permit the chamber height to approximate the mean size of the separators. During use, the biologic fluid to be analyzed is disposed within the chamber.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: March 3, 2020
    Assignee: Abbott Laboratories
    Inventor: Stephen C. Wardlaw
  • Publication number: 20190374943
    Abstract: A biological fluid analysis cartridge is provided. In certain embodiments, the cartridge includes a base plate extending between a sample handling portion and an analysis chamber portion. A handling upper panel is attached to the base plate within the sample handling portion. A collection port is at least partially formed with the handling upper panel. An initial channel and a secondary channel are formed between the handling upper panel and the base plate. The collection port and initial and secondary channels are in fluid communication with one another. A chamber upper panel is attached to the base plate within the analysis chamber portion. At least one analysis chamber is formed between the chamber upper panel and the base plate. The secondary channel and the analysis chamber are in fluid communication with one another.
    Type: Application
    Filed: August 26, 2019
    Publication date: December 12, 2019
    Inventors: John A. Verrant, Niten V. Lalpuria, Igor Nikonorov, Darryn W. Unfricht, Benjamin Ports, Stephen C. Wardlaw, Robert A. Levine, Robert Holt, Kyle Hukari
  • Publication number: 20190346362
    Abstract: An apparatus and a method for identifying at least one type of white blood cell (WBC) within a whole blood sample is provided. The method includes: adding at least one colorant to the sample; providing at least one fluorescent excitation light and at least one transmission light; receiving both light fluorescing from and transmitted through the sample and producing signals representative thereof; creating at least one image of the sample using the signals; identifying WBCs within the sample image; quantitatively analyzing at least some of the identified WBCs within the image, including determining one or more quantitative values; and identifying at least one type of WBC from the identified WBCs using the quantitative values.
    Type: Application
    Filed: July 29, 2019
    Publication date: November 14, 2019
    Inventors: David Herzog, Zhizhou Wang, Stephen C. Wardlaw, Min Xie
  • Patent number: 10391487
    Abstract: A biological fluid analysis cartridge is provided. In certain embodiments, the cartridge includes a base plate extending between a sample handling portion and an analysis chamber portion. A handling upper panel is attached to the base plate within the sample handling portion. A collection port is at least partially formed with the handling upper panel. An initial channel and a secondary channel are formed between the handling upper panel and the base plate. The collection port and initial and secondary channels are in fluid communication with one another. A chamber upper panel is attached to the base plate within the analysis chamber portion. At least one analysis chamber is formed between the chamber upper panel and the base plate. The secondary channel and the analysis chamber are in fluid communication with one another.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: August 27, 2019
    Assignee: Abbott Point of Care, Inc.
    Inventors: John A. Verrant, Niten V. Lalpuria, Igor Nikonorov, Darryn W. Unfricht, Benjamin Ports, Stephen C. Wardlaw, Robert A. Levine, Robert Holt, Kyle Hukari
  • Patent number: 10365203
    Abstract: A method and apparatus for identifying one or more target constituents (e.g., white blood cells) within a biological sample is provided. The method includes the steps of: a) adding at least one colorant to the sample; b) disposing the sample into a chamber defined by at least one transparent panel; c) creating at least one image of the sample quiescently residing within the chamber; d) identifying target constituents within the sample image; e) quantitatively analyzing at least some of the identified target constituents within the image relative to one or more predetermined quantitatively determinable features; and f) identifying at least one type of target constituent within the identified target constituents using the quantitatively determinable features.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: July 30, 2019
    Assignee: Abbott Point of Care, Inc.
    Inventors: David Herzog, Zhizhou Wang, Stephen C. Wardlaw, Min Xie
  • Patent number: 10203275
    Abstract: A method and apparatus for identifying one or more target constituents (e.g., white blood cells) within a biological sample is provided. The method includes the steps of: a) adding at least one colorant to the sample; b) disposing the sample into a chamber defined by at least one transparent panel; c) creating at least one image of the sample quiescently residing within the chamber; d) identifying target constituents within the sample image; e) quantitatively analyzing at least some of the identified target constituents within the image relative to one or more predetermined quantitatively determinable features; and f) identifying at least one type of target constituent within the identified target constituents using the quantitatively determinable features.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: February 12, 2019
    Assignee: Abbott Point of Care, Inc.
    Inventors: David Herzog, Zhizhou Wang, Stephen C. Wardlaw, Min Xie
  • Publication number: 20190017987
    Abstract: A method and apparatus for analyzing a biologic fluid sample for at least one target analyte is provided. The method includes providing an analysis chamber having at least one optically responsive chemical sensor (ORCS), sample and calibration fluid regions, and at least one fluid separator that separates the sample and calibration fluid regions. A first portion of each sensor is disposed in the sample fluid region and a second portion of each sensor is disposed in the calibration fluid region. The ORCS is configured to optically respond in the presence of the target analyte and when interrogated with one or more predetermined wavelengths of light. The method further includes disposing at least one calibration fluid having target analyte in a known or ascertainable concentration in the calibration fluid region, and disposing the biologic fluid sample in the sample fluid region.
    Type: Application
    Filed: October 14, 2016
    Publication date: January 17, 2019
    Inventors: Robert A. LEVINE, Stephen C. WARDLAW
  • Publication number: 20180348196
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 6, 2018
    Inventors: Min Xie, Stephen C. Wardlaw
  • Patent number: 10048248
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: August 14, 2018
    Assignee: Abbott Point of Care, Inc.
    Inventors: Min Xie, Stephen C. Wardlaw
  • Publication number: 20180156773
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 7, 2018
    Inventors: Min Xie, Stephen C. Wardlaw
  • Publication number: 20180141045
    Abstract: A biological fluid analysis cartridge is provided. In certain embodiments, the cartridge includes a base plate extending between a sample handling portion and an analysis chamber portion. A handling upper panel is attached to the base plate within the sample handling portion. A collection port is at least partially formed with the handling upper panel. An initial channel and a secondary channel are formed between the handling upper panel and the base plate. The collection port and initial and secondary channels are in fluid communication with one another. A chamber upper panel is attached to the base plate within the analysis chamber portion. At least one analysis chamber is formed between the chamber upper panel and the base plate. The secondary channel and the analysis chamber are in fluid communication with one another.
    Type: Application
    Filed: January 22, 2018
    Publication date: May 24, 2018
    Inventors: John A. Verrant, Niten V. Lalpuria, Igor Nikonorov, Darryn W. Unfricht, Benjamin Ports, Stephen C. Wardlaw, Robert A. Levine, Robert Holt, Kyle Hukari
  • Patent number: 9885701
    Abstract: A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: February 6, 2018
    Assignee: Abbott Point of Care, Inc.
    Inventors: Min Xie, Stephen C. Wardlaw
  • Patent number: 9873118
    Abstract: A biological fluid analysis cartridge is provided. In certain embodiments, the cartridge includes a base plate extending between a sample handling portion and an analysis chamber portion. A handling upper panel is attached to the base plate within the sample handling portion. A collection port is at least partially formed with the handling upper panel. An initial channel and a secondary channel are formed between the handling upper panel and the base plate. The collection port and initial and secondary channels are in fluid communication with one another. A chamber upper panel is attached to the base plate within the analysis chamber portion. At least one analysis chamber is formed between the chamber upper panel and the base plate. The secondary channel and the analysis chamber are in fluid communication with one another.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: January 23, 2018
    Assignee: Abbott Point of Care, Inc.
    Inventors: John A. Verrant, Niten V. Lalpuria, Igor Nikonorov, Darryn W. Unfricht, Benjamin Ports, Stephen C. Wardlaw, Robert A. Levine, Robert Holt, Kyle Hukari
  • Publication number: 20170336386
    Abstract: A method for analyzing a blood sample is provided that includes the steps of: providing a blood sample having one or more of each first and second constituents; admixing a colorant with the sample, which colorant is operative to cause the first constituents and second constituents to fluoresce and absorb light; illuminating at least a portion of the sample; e) imaging a portion of the sample; determining a fluorescence value for each the first constituents and second constituents; determining an optical density value for each of the first constituents and second constituents; and identifying the first constituents and the second constituents using the determined fluorescence and optical density values.
    Type: Application
    Filed: August 10, 2017
    Publication date: November 23, 2017
    Inventors: Robert A. Levine, Stephen C. Wardlaw, Niten V. Lalpuria, Darryn W. Unfricht
  • Publication number: 20170299497
    Abstract: A method and an apparatus for enumerating one or more specific elements within a biologic fluid sample are provided. An embodiment of the method includes the steps of: a) providing a chamber formed between a first planar member that is transparent and a second planar member, which members are separated from one another by a substantially uniform height; b) introducing the biologic fluid sample into the chamber, wherein the chamber height is sized such that the sample extends between the first and second members, and sized relative to the specific elements within the sample such that the specific elements non-uniformly distribute within the sample upon introduction into the chamber; c) examining substantially all of the sample within the chamber and enumerating all of at least one of the specific elements; d) determining the volume of sample contained within the chamber, and e) determining the number of the at least one of the specific elements per unit volume.
    Type: Application
    Filed: July 3, 2017
    Publication date: October 19, 2017
    Inventor: Stephen C. Wardlaw
  • Patent number: 9733233
    Abstract: A method for analyzing a blood sample is provided that includes the steps of: providing a blood sample having one or more of each first and second constituents; admixing a colorant with the sample, which colorant is operative to cause the first constituents and second constituents to fluoresce and absorb light; illuminating at least a portion of the sample; e) imaging a portion of the sample; determining a fluorescence value for each the first constituents and second constituents; determining an optical density value for each of the first constituents and second constituents; and identifying the first constituents and the second constituents using the determined fluorescence and optical density values.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: August 15, 2017
    Assignee: Abbott Point of Care, Inc.
    Inventors: Robert A. Levine, Stephen C. Wardlaw, Niten V. Lalpuria, Darryn W. Unfricht