Patents by Inventor Stephen Charles Case-Green

Stephen Charles Case-Green has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for analysing polynucleotide targets using tethered oligonucleotide probes
    Patent number: 8084211
    Abstract: A method of analysing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analysed. Arrays of immobilised oligonucleotides are provided for use in the method.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: December 27, 2011
    Assignee: Oxford Gene Technology IP Limited
    Inventors: Edwin Mellor Southern, Clare Elizabeth Pritchard, Stephen Charles Case-Green
  • Methods for analyzing polynucleotide targets using tethered oligonucleotide probes
    Patent number: 7192707
    Abstract: A method of analyzing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilized oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analyzed. Arrays of immobilized oligonucleotides are provided for use in the method.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: March 20, 2007
    Assignee: Oxford Gene Technology IP Limited
    Inventors: Edwin Mellor Southern, Clare Elizabeth Pritchard, Stephen Charles Case-Green
  • Method for analysing a polynucleotide containing a variable sequence and a set or array of oligonucleotides therefor
    Patent number: 6770751
    Abstract: A method of analysing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilized oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analyzed. Arrays of immobilized oligonucleotides are provided for use in the method.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: August 3, 2004
    Assignee: Oxford Gene Technology IP Limited
    Inventors: Edwin Mellor Southern, Clare Elizabeth Pritchard, Stephen Charles Case-Green
  • Method for analysing a polynucleotide containing a variable sequence and a set or array of oligonucleotides therefor
    Publication number: 20020106665
    Abstract: A method of analysing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilized oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analyzed. Arrays of immobilized oligonucleotides are provided for use in the method.
    Type: Application
    Filed: August 23, 2001
    Publication date: August 8, 2002
    Inventors: Edwin Mellor Southern, Clare Elizabeth Pritchard, Stephen Charles Case-Green
  • Methods of determining polynuceotide intramolecular structure
    Publication number: 20020031766
    Abstract: A method of identifying one or a combination of ligands, e.g. oligonucleotides or analogues, that interact specifically with a target, e.g. a DNA or an RNA molecule having a secondary or tertiary structure. One ligand may be pre-reacted to open up the target for interaction with other ligands forming an array on a solid surface.
    Type: Application
    Filed: April 26, 2000
    Publication date: March 14, 2002
    Inventors: Edwin Mellor Southern, Mir Kalim Ullah, Stephen Charles Case-Green
  • Method for analyzing a polynucleotide containing a variable sequence and a set or array of oligonucleotides therefor
    Patent number: 6307039
    Abstract: A method of analyzing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analyzed. Arrays of immobilised oligonucleotides are provided for use in the method.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: October 23, 2001
    Assignee: Oxford Gene Technology Limited
    Inventors: Edwin Mellor Southern, Clare Elizabeth Pritchard, Stephen Charles Case-Green
  • Method for analyzing a polynucleotide containing a variable sequence
    Patent number: 6150095
    Abstract: A method of analyzing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilised oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analysed. Arrays of immobilised oligonucleotides are provided for use in the method.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: November 21, 2000
    Assignee: Oxford Gene Technology Limited
    Inventors: Edwin Mellor Southern, Clare Elizabeth Pritchard, Stephen Charles Case-Green
  • Methods for discovering ligands
    Patent number: 6080585
    Abstract: A method of identifying one or a combination of ligands, e.g. oligonucleotides or analogues, that interact specifically with a target, e.g. a DNA or an RNA molecule having a secondary or tertiary structure. One ligand may be pre-reacted to open up the target for interaction with other ligands forming an array on a solid surface.
    Type: Grant
    Filed: October 2, 1996
    Date of Patent: June 27, 2000
    Assignee: Oxford Gene Technology Limited
    Inventors: Edwin Mellor Southern, Kalim Ullah Mir, Stephen Charles Case-Green