Patents by Inventor Stephen Chim

Stephen Chim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS FOR PREMATURE BIRTH
    Publication number: 20160376651
    Abstract: The present invention provides a method for determining increased risk of premature birth in a pregnant woman by detecting altered expression level of one or more marker genes in the woman's blood. A kit and device useful for such a method are also provided. In addition, the present invention provides a method for preventing or reducing the likelihood of premature birth.
    Type: Application
    Filed: June 20, 2014
    Publication date: December 29, 2016
    Inventors: Siu-Chung Stephen CHIM, Chee Yin CHEUNG, Wan Chee CHEUNG, Tak Yeung EUNG, Wing Shan LEE
  • Method for detecting chromosomal aneuploidy
    Patent number: 8563242
    Abstract: The present invention relates to a new, non-invasive method for detecting chromosomal aneuploidy by analyzing a sample from a pregnant woman. The detection is based on the ratio between the amount of a fetal methylation marker located on a chromosome relevant to the aneuploidy and the amount of a fetal genetic marker located on a reference chromosome, offering improved accuracy.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: October 22, 2013
    Assignee: The Chinese University of Hong Kong
    Inventors: Yuk Ming Dennis Lo, Rossa Wai Kwun Chiu, Yu Kwan Tong, Shengnan Jin, Siu Chung Stephen Chim, Wai Yi Tsui
  • METHOD FOR DETECTING CHROMOSOMAL ANEUPLOIDY
    Publication number: 20110039724
    Abstract: The present invention relates to a new, non-invasive method for detecting chromosomal aneuploidy by analyzing a sample from a pregnant woman. The detection is based on the ratio between the amount of a fetal methylation marker located on a chromosome relevant to the aneuploidy and the amount of a fetal genetic marker located on a reference chromosome, offering improved accuracy.
    Type: Application
    Filed: July 9, 2010
    Publication date: February 17, 2011
    Applicant: The Chinese University of Hong Kong
    Inventors: Yuk Ming Dennis Lo, Rossa Wai Kwun Chiu, Yu Kwan Tong, Shengnan Jin, Siu Chung Stephen Chim, Wai Yi Tsui
  • COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING SEVERE ACUTE RESPIRATORY SYNDROME (SARS)
    Publication number: 20080286756
    Abstract: The present invention relates to the fields of immunochemistry and pharmacology. Methods and compositions are described for the diagnosis and treatment of SARS CoV infection. More specifically, the application discloses nucleic acids and peptides of the spike glycoprotein of SARS CoV that provide prognostic and therapeutic compositions in treatment of individuals contracting, or in danger of contracting SARS CoV. The peptides of the invention are also useful in producing antibodies against the SARS CoV glycoprotein.
    Type: Application
    Filed: April 3, 2008
    Publication date: November 20, 2008
    Applicant: THE CHINESE UNIVERSITY OF HONG KONG
    Inventors: Kwok Wing TSUI, Kwok Pui Fung, Mary Miu Yee Waye, Yuk Ming Dennis Lo, Siu Chung Stephen Chim, Wai Kwun Rossa Chiu, Siu Lun John Tam, Kay Sheung Paul Chan
  • Compositions and methods for diagnosing and treating severe acute respiratory syndrome (SARS)
    Patent number: 7371525
    Abstract: The present invention relates to the fields of immunochemistry and pharmacology. Methods and compositions are described for the diagnosis and treatment of SARS CoV infection. More specifically, the application discloses nucleic acids and peptides of the spike glycoprotein of SARS CoV that provide prognostic and therapeutic compositions in treatment of individuals contracting, or in danger of contracting SARS CoV. The peptides of the invention are also useful in producing antibodies against the SARS CoV glycoprotein.
    Type: Grant
    Filed: July 28, 2004
    Date of Patent: May 13, 2008
    Assignee: The Chinese University of Hong Kong
    Inventors: Kwok Wing Tsui, Siu Chung Stephen Chim, Mary Miu Yee Waye, Kwok Pui Fung, Yuk Ming Dennis Lo, Wai Kwun Rossa Chiu, Siu Lun John Tam, Kay Sheung Paul Chan
  • Novel markers for prenatal diagnosis and monitoring
    Publication number: 20070275402
    Abstract: This application provides the use of novel fetal markers for prenatal diagnosis and monitoring of certain pregnancy-related conditions. More specifically, the invention resides in the discovery that certain CpG islands located on fetal chromosome 21 demonstrate a methylation profile that is distinct from that of the corresponding CpG islands located on maternal chromosome 21. This application also provides kits for diagnosing or monitoring of the relevant conditions.
    Type: Application
    Filed: April 6, 2007
    Publication date: November 29, 2007
    Applicant: The Chinese University of Hong Kong
    Inventors: Yuk Lo, Rossa Chiu, Stephen Chim, Chunming Ding, Shengnan Jin, Tracy Lee, Fiona Lun
  • Marker for prenatal diagnosis and monitoring
    Publication number: 20060019278
    Abstract: The present invention relates to new methods for diagnosing a pregnancy-associated disorder by analyzing fetal DNA present in the mother's blood. More specifically, this invention relies on the discovery that the maspin gene is differentially methylated in fetal DNA and in maternal DNA and provides these new diagnostic methods, which distinguish fetal DNA from maternal DNA and detect prenatal disorders based on abnormalities in fetal DNA level and methylation status.
    Type: Application
    Filed: June 3, 2005
    Publication date: January 26, 2006
    Applicant: The Chinese University of Hong Kong
    Inventors: Yuk Ming Lo, Rossa Chiu, Stephen Chim, Yu-kwan Tong, Chunming Ding