Patents by Inventor Stephen Cobbold

Stephen Cobbold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of tolerizing a primate to an antigen
    Patent number: 7947272
    Abstract: Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: May 24, 2011
    Assignees: Tolerx, Inc., Isis Innovation, Ltd., Cambridge University Technical Services, Ltd.
    Inventors: Mark Frewin, Herman Waldmann, Scott Gorman, Geoff Hale, Patricia Rao, Tadeusz Kornaga, Douglas Ringler, Stephen Cobbold, Dawn Winsor-Hines
  • Compositions and methods of tolerizing a primate to an antigen
    Publication number: 20110008330
    Abstract: Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.
    Type: Application
    Filed: March 5, 2010
    Publication date: January 13, 2011
    Inventors: Mark Frewin, Herman Waldmann, Scott Gorman, Geoff Hale, Patricia Rao, Tadeusz Komaga, Douglas Ringler, Stephen Cobbold, Dawn Winsor-Hines
  • Anti-CD4 antibodies
    Patent number: 7541443
    Abstract: Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.
    Type: Grant
    Filed: January 29, 2003
    Date of Patent: June 2, 2009
    Assignees: Tolerrx, Inc., Isis Innovation, Ltd., Cambridge University Technical Services, Ltd.
    Inventors: Mark Frewin, Herman Waldmann, Scott Gorman, Geoff Hale, Patricia Rao, Tadeusz Kornaga, Douglas Ringler, Stephen Cobbold, Dawn Winsor-Hines
  • Compositions and methods of tolerizing a primate to an antigen
    Publication number: 20080160016
    Abstract: Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.
    Type: Application
    Filed: July 13, 2006
    Publication date: July 3, 2008
    Inventors: Mark Frewin, Herman Waldmann, Scott Gorman, Geoff Hale, Patricia Rao, Tadeusz Kornaga, Douglas Ringler, Stephen Cobbold, Dawn Winsor-Hines
  • Altered antibodies and their preparation
    Publication number: 20070212753
    Abstract: An altered antibody chain is produced in which the CDR's of the variable domain of the chain are derived from a first mammalian species. The framework-encoding regions of DNA encoding the variable domain of the first species are mutated so that the mutated framework-encoding regions encode a framework derived from a second different mammalian species. The or each constant domain of the antibody chain, if present, are also derived from the second mammalian species. An antibody which is capable of binding to human CD4 antigen is also provided together with a pharmaceutical composition comprising the antibody.
    Type: Application
    Filed: April 26, 2005
    Publication date: September 13, 2007
    Applicant: BURROUGHS WELLCOME CO.
    Inventors: Scott Gorman, Michael Clark, Stephen Cobbold, Herman Waldmann
  • Compositions and methods of tolerizing a primate to an antigen
    Publication number: 20030219403
    Abstract: Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.
    Type: Application
    Filed: January 29, 2003
    Publication date: November 27, 2003
    Inventors: Mark Frewin, Herman Waldmann, Scott Gorman, Geoff Hale, Patricia Rao, Tadeusz Kornaga, Douglas Ringler, Stephen Cobbold, Dawn Winsor-Hines
  • TRX1 antibody and uses therefor
    Publication number: 20030108518
    Abstract: Inducing tolerance in a primate by use of a compound that has certain characteristics when tested in vitro. The compound is preferably TRX1 antibody and the compound is preferably used in accordance with a specified dosing regimen.
    Type: Application
    Filed: June 13, 2002
    Publication date: June 12, 2003
    Inventors: Mark Frewin, Herman Waldmann, Scott Gorman, Geoff Hale, Patricia Rao, Tadeusz Kornaga, Douglas Ringler, Stephen Cobbold, Dawn Winsor-Hines