Patents by Inventor Stephen Condon

Stephen Condon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Smac Mimetic Therapy
    Publication number: 20130196927
    Abstract: A Smac mimetic therapy wherein the Smac mimetic is selected and developed based at least in part on its cIAP degradation properties.
    Type: Application
    Filed: January 28, 2013
    Publication date: August 1, 2013
    Inventors: Christopher BENETATOS, Srinivas CHUNDURU, Stephen CONDON, Mark McKINLAY, Yasuhiro MITSUUCHI
  • RETROVIRAL PROTEASE INHIBITING COMPOUNDS
    Publication number: 20080139811
    Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: February 27, 2007
    Publication date: June 12, 2008
    Inventors: Hing Sham, Daniel Norbeck, Xiaoqi Chen, David Betebenner, Dale Kempf, Thomas Herrin, Gondi Kumar, Stephen Condon, Arthur Cooper, Daniel Dickman, Steven Hannick, Lawrence Kolaczkowski, Patricia Oliver, Daniel Plata, Peter Stengel, Eric Stoner, Jieh-Heh Tien, Jih-Hua Liu, Ketan Patel
  • DIMERIC IAP INHIBITORS
    Publication number: 20080020986
    Abstract: Smac mimetics that inhibit IAPs.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 24, 2008
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • IAP INHIBITORS
    Publication number: 20080021066
    Abstract: Smac mimetics that inhibit IAPs.
    Type: Application
    Filed: July 24, 2007
    Publication date: January 24, 2008
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • Pyranouidole Derivatives and the Use Thereof for the Treatment of Hepatitis C Virus Infection or Disease
    Publication number: 20070219212
    Abstract: The invention is directed to novel pyranoindole derivatives and analogs as well as compositions containing the same and to the use thereof for the treatment, prevention or inhibition of viral infections and associated diseases caused by the Hepatitis C virus.
    Type: Application
    Filed: March 1, 2005
    Publication date: September 20, 2007
    Inventors: Stephen Condon, Randy Jackson, Matthew Laporte, Christopher Burns, Torsten Herbertz, Janet Gaboury
  • BUSINESS METHODS FOR COMPOUNDS FOR TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20070203749
    Abstract: Methods and systems for marketing pharmaceutical compositions including cIAP binding compounds are described herein.
    Type: Application
    Filed: February 14, 2007
    Publication date: August 30, 2007
    Inventors: Sri Chunduru, Mark McKinlay, Stacy Springs, Chris Benetatos, Stephen Condon
  • Dimeric IAP inhibitors
    Publication number: 20060194741
    Abstract: Molecular mimics of Smac are capable of modulating apoptosis through their interaction with cellular IAPs (inhibitor of apoptosis proteins). The mimetics are based on a monomer or dimer of the N-terminal tetrapeptide of IAP-binding proteins, such as Smac/DIABLO, Hid, Grim and Reaper, which interact with a specific surface groove of LAP. Also disclosed are methods of using these peptidomimetics for therapeutic purposes.
    Type: Application
    Filed: February 27, 2006
    Publication date: August 31, 2006
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Patent number: 7074932
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Grant
    Filed: May 7, 2003
    Date of Patent: July 11, 2006
    Inventors: Michael S. Allen, Ramiya H. Premchandran, Sou-Jen Chang, Stephen Condon, John A. DeMattei, Steven A. King, Lawrence Kolaczkowski, Sukumar Manna, Paul J. Nichols, Hemant H. Patel, Subhash R. Patel, Daniel J. Plata, Eric J. Stoner, Jien-Heh J. Tien, Steven J. Wittenberger
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Publication number: 20060128962
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Application
    Filed: February 6, 2006
    Publication date: June 15, 2006
    Inventors: Michael Allen, Ramiya Premchandran, Sou-Jen Chang, Stephen Condon, John DeMattei, Steven King, Lawrence Kolaczkowski, Sukumar Manna, Paul Nichols, Hemant Patel, Subhash Patel, Daniel Plata, Eric Stoner, Jien-Heh Tien, Steven Wittenberger
  • IAP binding compounds
    Publication number: 20060025347
    Abstract: IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells and may be used to modify apoptosis in cells treated with such molecules. Embodiments of these compounds have a Kd of less that 0.1 micromolar. Methods of using these IAP binding molecules for therapeutic, diagnostic, and assay purposes are also disclosed.
    Type: Application
    Filed: July 15, 2005
    Publication date: February 2, 2006
    Inventors: Stephen Condon, Matthew LaPorte, Yijun Deng, Susan Rippin
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Publication number: 20030199696
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Application
    Filed: May 7, 2003
    Publication date: October 23, 2003
    Inventors: Michael S. Allen, Ramiya H. Premchandran, Sou-Jen Chang, Stephen Condon, John A. DeMattei, Steven A. King, Lawrence Kolaczkowski, Sukumar Manna, Paul J. Nichols, Hemant H. Patel, Subhash R. Patel, Daniel J. Plata, Eric J. Stoner, Jien-Heh J. Tien, Steven J. Wittenberger
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Patent number: 6579986
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: June 17, 2003
    Assignee: Abbott Laboratories
    Inventors: Michael S. Allen, Ramiya H. Premchandran, Sou-Jen Chang, Stephen Condon, John A. DeMattei, Steven A. King, Lawrence Kolaczkowski, Sukumar Manna, Paul J. Nichols, Hemant H. Patel, Subhash R. Patel, Daniel J. Plata, Eric J. Stoner, Jien-Heh J. Tien, Steven J. Wittenberger
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Publication number: 20020165390
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Application
    Filed: April 29, 2002
    Publication date: November 7, 2002
    Inventors: Michael S. Allen, Ramiya H. Premchandran, Sou-Jen Chang, Stephen Condon, John A. DeMattei, Steven A. King, Lawrence Kolaczkowski, Sukumar Manna, Paul J. Nichols, Hemant H. Patel, Subhash R. Patel, Daniel J. Plata, Eric J. Stoner, Jien-Heh J. Tien, Steven J. Wittenberger
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Patent number: 6417366
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: July 9, 2002
    Assignee: Abbott Laboratories
    Inventors: Michael S. Allen, Ramiya H. Premchandran, Sou-Jen Chang, Stephen Condon, John A. DeMattei, Steven A. King, Lawrence Kolaczkowski, Sukumar Manna, Paul J. Nichols, Hemant H. Patel, Subhash R. Patel, Daniel J. Plata, Eric J. Stoner, Jien-Heh J. Tien, Steven J. Wittenberger
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Publication number: 20020013468
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Application
    Filed: March 3, 2000
    Publication date: January 31, 2002
    Inventors: Michael S. Allen, Ramiya H. Premchandran, Sou-Jen Chang, Stephen Condon, John A. DeMattei, Steven A. King, Lawrence Kolaczkowski, Sukumar Manna, Paul Nichols, Hermant H. Patel, Subhash R. Patel, Daniel J. Plata, Eric J. Stoner, Jien-Heh J. Tien, Steven J. Wittenberger
  • Substituted &bgr;-thiocarboxylic acids
    Patent number: 6306873
    Abstract: This invention relates to compounds of general formula (I): in which Ar is a group selected from: A1, A2, B, C, D, E, Q1-Q3, R1-R9, Z1 and Z2 are as defined in the disclosure, and Y represents carboxy or an acid bioisostere. These compounds inhibit the production or physiological effects of TNF and inhibit cyclic AMP phosphodiesterase. The invention is also directed to pharmaceutical compositions comprising compounds of formula (I), their pharmaceutical use and methods for their preparation.
    Type: Grant
    Filed: July 20, 1999
    Date of Patent: October 23, 2001
    Assignee: Aventis Pharmaceuticals Products Inc.
    Inventors: Christopher J. Burns, Richard Labaudiniere, Stephen Condon, Robert D. Groneberg, Rose M. Mathew, Joseph M. Salvino