Patents by Inventor Stephen D. Penrose

Stephen D. Penrose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10457675
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: October 29, 2019
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20190062321
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use.
    Type: Application
    Filed: July 30, 2018
    Publication date: February 28, 2019
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10106535
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: October 23, 2018
    Assignee: CHDI FOUNDATION, INC.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10065948
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: September 4, 2018
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20170305900
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: April 7, 2017
    Publication date: October 26, 2017
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9783488
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 10, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Gilles Raphy, Alan F. Haughan, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Perla Breccia, Grant Wishart, Samantha J. Hughes, Daniel R. Allen, Stephen D. Penrose
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20170101402
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.
    Type: Application
    Filed: June 1, 2015
    Publication date: April 13, 2017
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Roland W. Bürli, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebeca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9617259
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: April 11, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160039745
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: March 10, 2014
    Publication date: February 11, 2016
    Inventors: Celia Dominguez, Ignacio Muñoz-San Juan, Michel Maillard, Gilles Raphy, Alan F. Haughan, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Burli, Grant Wishart, Samantha J. Hughes, Daniel R. Allen, Stephen D. Penrose, Perla Breccia
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160031876
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: March 10, 2014
    Publication date: February 4, 2016
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes