Patents by Inventor Stephen del Cardayre

Stephen del Cardayre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of fatty acid esters
    Patent number: 11434512
    Abstract: Methods of producing fatty acid esters, such as fatty acid ethyl esters, from genetically engineered microorganisms are described.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: September 6, 2022
    Assignee: Genomatica, Inc.
    Inventors: Fernando Sanchez-Riera, Stephen Del Cardayre, Fernando Valle
  • PRODUCTION OF FATTY ACID ESTERS
    Publication number: 20200017890
    Abstract: Methods of producing fatty acid esters, such as fatty acid ethyl esters, from genetically engineered microorganisms are described.
    Type: Application
    Filed: December 27, 2018
    Publication date: January 16, 2020
    Inventors: Fernando Sanchez-Riera, Stephen Del Cardayre, Fernando Valle
  • Microbial production of alkanolamides and amidoamines and uses thereof
    Patent number: 9683247
    Abstract: The disclosure relates to a recombinant microorganism engineered to express an enzyme which catalyzes the conversion of a primary amine and an acyl thioester to a fatty amide. The disclosure further encompasses a method of producing a fatty amide by culturing the recombinant microorganism in the presence of a carbon source.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: June 20, 2017
    Assignee: REG LIFE SCIENCES, LLC
    Inventors: Jason J. Lutes, Stephen del Cardayre
  • MICROBIAL PRODUCTION OF ALKANOLAMIDES AND AMIDOAMINES AND USES THEREOF
    Publication number: 20150079643
    Abstract: The disclosure relates to a recombinant microorganism engineered to express an enzyme which catalyzes the conversion of a primary amine and an acyl thioester to a fatty amide. The disclosure further encompasses a method of producing a fatty amide by culturing the recombinant microorganism in the presence of a carbon source.
    Type: Application
    Filed: March 12, 2013
    Publication date: March 19, 2015
    Applicant: REG Life Sciences, LLC.
    Inventors: Jason J. Lutes, Stephen del Cardayre
  • EVOLUTION OF WHOLE CELLS AND ORGANISMS BY RECURSIVE SEQUENCE RECOMBINATION
    Publication number: 20120252681
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: December 2, 2011
    Publication date: October 4, 2012
    Applicant: CODEXIS MAYFLOWER HOLDINGS, LLC
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem P.C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda A. Castle, Claus M. Krebber, Steven H. Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph A. Affholter
  • METHODS FOR IDENTIFYING SETS OF OLIGONUCLEOTIDES FOR USE IN AN IN VITRO RECOMBINATION PROCEDURE
    Publication number: 20110257892
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: April 27, 2011
    Publication date: October 20, 2011
    Applicant: CODEXIS MAYFLOWER HOLDINGS, LLC
    Inventors: Sergey A. Selifonov, Willem P.C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • EVOLUTION OF WHOLE CELLS AND ORGANISMS BY RECURSIVE SEQUENCE RECOMBINATION
    Publication number: 20110190140
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: October 15, 2009
    Publication date: August 4, 2011
    Applicant: Maxygen, Inc.
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem P.C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda A. Castle, Claus M. Krebber, Steven H. Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph A. Affholter
  • Methods for identifying and producing polypeptides
    Patent number: 7957912
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided. One disclosed method involves identifying and producing a polypeptide. The method may involve (a) receiving data identifying sequences of two or more parental polypeptides or parental nucleic acids that encode the polypeptides; (b) selecting one or more cross-over sites on the sequences thereby defining one or more recombinant polypeptides or recombinant nucleic acids; (c) selecting at least one of the recombinant polypeptides or recombinant nucleic acids; (d) recombining one or more oligonucleotides, at least one of which has a sequence matching some or all of that of the recombinant polypeptides or recombinant nucleic acids selected in (c); (e) selecting at least some of the recombined oligonucleotides produced in (d); and (f) producing a polypeptide encoded by the selected nucleic acid.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: June 7, 2011
    Assignee: Codexis Mayflower Holdings LLC
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Methods for identifying sets of oligonucleotides for use in an in vitro recombination procedures
    Patent number: 7904249
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators are used to identify sets of oligonucleotides for in vitro recombination. In certain embodiments, the methods involve inputting amino acid sequence character strings into a digital system and back-translating the amino acid character strings into a plurality of nucleic acid character strings. The nucleic acid character strings are then processed to define and select at least one recombinant nucleic acid for use in identifying one or more oligonucleotides for in vitro recombination.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: March 8, 2011
    Assignee: Codexis Mayflower Holding, LLC
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Method for making polynucleotides having desired characteristics
    Patent number: 7853410
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: December 14, 2010
    Assignee: Codexis, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • PRODUCTION OF FATTY ACID ESTERS
    Publication number: 20100274033
    Abstract: Methods of producing fatty acid esters, such as fatty acid ethyl esters, from genetically engineered microorganisms are described.
    Type: Application
    Filed: April 27, 2010
    Publication date: October 28, 2010
    Applicant: LS9, Inc.
    Inventors: Fernando Sanchez-Riera, Stephen Del Cardayre, Fernando Valle
  • PRODUCTION OF FATTY ACID DERIVATIVES
    Publication number: 20100257778
    Abstract: Methods and compositions for producing fatty acid derivatives, for example, fatty esters, are described.
    Type: Application
    Filed: April 11, 2010
    Publication date: October 14, 2010
    Applicant: LS9, Inc.
    Inventors: Alfred Gaertner, Andreas Schirmer, Fernando Valle, Stephen Del Cardayre
  • SYSTEMS AND METHODS FOR THE PRODUCTION OF FATTY ESTERS
    Publication number: 20100199548
    Abstract: Disclosed herein are various embodiments regarding the use of impure and/or unrefined alcohol in the production of fatty esters. Various production hosts that are capable of producing a fatty ester from an impure or unrefined alcohol are also disclosed.
    Type: Application
    Filed: July 2, 2008
    Publication date: August 12, 2010
    Applicant: LS9, Inc.
    Inventors: Stephen del Cardayre, Michael Charles Milner Cockrem
  • METHODS FOR IDENTIFYING SETS OF OLIGONUCLEOTIDES FOR USE IN AN IN VITRO RECOMBINATION PROCEDURE
    Publication number: 20100056385
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: September 10, 2009
    Publication date: March 4, 2010
    Applicant: MAXYGEN, INC.
    Inventors: Sergey A. Selifonov, Willem P.C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Methods for identifying sets of oligonucleotides for use in an in vitro recombination procedure
    Patent number: 7620502
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators are used to identify sets of oligonucleotides for in vitro recombination.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: November 17, 2009
    Assignee: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Publication number: 20080318795
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: October 31, 2007
    Publication date: December 25, 2008
    Applicant: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P.C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Identifying oligonucleotides for in vitro recombination
    Patent number: 7421347
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: September 2, 2008
    Assignee: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull
  • Evolution of whole cells and organisms by recursive sequence recombination
    Publication number: 20070026446
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: August 17, 2006
    Publication date: February 1, 2007
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem Stemmer, Jon Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus Krebber, Steven Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph Affholter
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Publication number: 20060142950
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: January 24, 2006
    Publication date: June 29, 2006
    Applicant: Maxygen, Inc
    Inventors: Sergey Selifonov, Willem Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip Patten, Jeremy Minshull, Lorraine Giver
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Patent number: 7058515
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: June 6, 2006
    Assignee: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver