Patents by Inventor Stephen Donovan

Stephen Donovan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Botulinum toxin formulation for oral administration
    Patent number: 9265722
    Abstract: Pharmaceutical compositions of a botulinum toxin for oral administration to a patient with a gastrointestinal disorder.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: February 23, 2016
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Transdermal botulinum toxin compositions
    Patent number: 9144692
    Abstract: Pharmaceutical compositions for transdermal administration of neurotoxins to a patient include a neurotoxin, such as a botulinum toxin, and an enhancing agent that facilitates absorption of the neurotoxin through the skin of the patient and does not eliminate the bioactivity associated with the neurotoxin. The pharmaceutical compositions are topically applied on a patient, and may be provided in a transdermal patch.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: September 29, 2015
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Animal product free system and process for purifying a botulinum toxin
    Patent number: 8841110
    Abstract: Chromatographic processes and systems for purifying a botulinum toxin from an APF fermentation medium.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: September 23, 2014
    Assignee: Allergan, Inc.
    Inventors: Hui Xiang, Mingjiang Luo, Ping Wang, Stephen Donovan
  • Animal product free system and process for purifying a botulinum toxin
    Patent number: 8409828
    Abstract: Chromatographic processes and systems for purifying a botulinum toxin from an APF fermentation medium.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: April 2, 2013
    Assignee: Allergan, Inc.
    Inventors: Hui Xiang, Mingjiang Luo, Ping Wang, Stephen Donovan
  • ANIMAL PRODUCT FREE SYSTEM AND PROCESS FOR PURIFYING A BOTULINUM TOXIN
    Publication number: 20120149089
    Abstract: Chromatographic processes and systems for purifying a botulinum toxin from an APF fermentation medium.
    Type: Application
    Filed: April 7, 2008
    Publication date: June 14, 2012
    Inventors: Hui Xiang, Mingjiang Luo, Ping Wang, Stephen Donovan
  • N-substituted azacycles
    Patent number: 8119563
    Abstract: N-substituted azacycle derivative compounds represented by formula (I): wherein m, q, r, t and u are independently selected from 0 or 1; and p is 0, 1, 2, or 3; and A, B, D, X, Y, R, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are fully described herein. The compounds being particularly useful in compositions comprising an insecticidally effective amount of at least one compound of formula I, and an insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: February 21, 2012
    Assignee: FMC Corporation
    Inventors: George Theodoridis, David Rosen, Shunxiang Zhang, Walter H. Yeager, Robert N. Henrie, II, Syed Z. Ahmed, Hongbin Men, Stephen Donovan
  • Clostridial toxin derivatives and methods for treating pain
    Patent number: 8017131
    Abstract: Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or fragment or derivative thereof, attached to a targeting moiety, wherein the targeting moiety is selected from a group consisting of transmission compounds which can be released from neurons upon the transmission of pain signals by the neurons, and compounds substantially similar to the transmission compounds.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: September 13, 2011
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Media for clostridium bacterium and processes for obtaining a clostridial toxin
    Patent number: 8012716
    Abstract: Animal product free (APF) media and processes for the culture and fermentation of botulinum toxin producing Clostridium botulinum bacteria. The botulinum toxin obtained can be used for formulating and compounding botulinum toxin pharmaceutical compositions. The APF media can contain significantly reduced levels of meat or dairy by-products and use non-animal based products instead of the animal-derived products. Preferably, the APF media used are substantially free or free of animal derived products.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: September 6, 2011
    Assignee: Allergan, Inc.
    Inventors: Stephen Donovan, Ping Wang
  • Animal product free media and processes for obtaining a botulinum toxin
    Patent number: 8008044
    Abstract: Media and processes for the fermentation of Clostridium botulinum and obtaining a botulinum toxin for use in formulating botulinum toxin pharmaceutical compositions. The growth media can contain significantly reduced levels of meat or dairy by-products using non-animal based products to replace the animal-derived products. Preferably, the media used are substantially free of animal derived products.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: August 30, 2011
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Methods for breast treatment
    Patent number: 7846456
    Abstract: A method for treating a mammary gland disorder, including hyperplastic, hypertonic, cystic and/or neoplastic mammary gland tissue by local administration of a botulinum toxin to or to the vicinity of the afflicted breast tissue.
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: December 7, 2010
    Assignee: Allergan, Inc.
    Inventors: Mitchell F. Brin, Stephen Donovan
  • Methods for treating diverse cancers
    Patent number: 7838008
    Abstract: Methods for treating diverse cancers by local administration of a botulinum toxin to or to the vicinity of the cancer.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: November 23, 2010
    Assignee: Allergan, Inc.
    Inventors: Mitchell F. Brin, Stephen Donovan
  • Methods for treating mammary gland disorders
    Patent number: 7838007
    Abstract: A method for treating a mammary gland disorder, including hyperplastic, hypertonic, cystic and/or neoplastic mammary gland tissue by local administration of a botulinum toxin to or to the vicinity of the afflicted breast tissue.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: November 23, 2010
    Assignee: Allergan, Inc.
    Inventors: Mitchell F. Brin, Stephen Donovan
  • Clostridial toxin derivatives and methods for treating pain
    Patent number: 7833535
    Abstract: Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or fragment or derivative thereof, attached to a targeting moiety, wherein the targeting moiety is selected from a group consisting of transmission compounds which can be released from neurons upon the transmission of pain signals by the neurons, and compounds substantially similar to the transmission compounds.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: November 16, 2010
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Botulinum toxin therapy for neuropsychiatric disorders
    Patent number: 7811587
    Abstract: Methods for treating psychiatric disorders include intracranial administration of a therapeutically effective amount of a neurotoxin, such as a botulinum toxin type A, to a human patient.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: October 12, 2010
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Clostridial toxin derivatives and methods for treating pain
    Patent number: 7780968
    Abstract: Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or fragment or derivative thereof, attached to a targeting moiety, wherein the targeting moiety is selected from a group consisting of transmission compounds which can be released from neurons upon the transmission of pain signals by the neurons, and compounds substantially similar to the transmission compounds.
    Type: Grant
    Filed: September 16, 2008
    Date of Patent: August 24, 2010
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Transdermal botulinum toxin administration
    Patent number: 7758871
    Abstract: Pharmaceutical compositions for transdermal administration of neurotoxins to a patient include a neurotoxin, such as a botulinum toxin, and an enhancing agent that facilitates absorption of the neurotoxin through the skin of the patient and does not eliminate the bioactivity associated with the neurotoxin. The pharmaceutical compositions are topically applied on a patient, and may be provided in a transdermal patch.
    Type: Grant
    Filed: September 29, 2003
    Date of Patent: July 20, 2010
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Clostridial toxin derivatives and methods for treating pain
    Patent number: 7736659
    Abstract: Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or fragment or derivative thereof, attached to a targeting moiety, wherein the targeting moiety is selected from a group consisting of transmission compounds which can be released from neurons upon the transmission of pain signals by the neurons, and compounds substantially similar to the transmission compounds.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: June 15, 2010
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Transdermal botulinum toxin administration for the treatment of spastic muscle pain
    Patent number: 7704524
    Abstract: Pharmaceutical compositions for transdermal administration of neurotoxins to a patient include a neurotoxin, such as a botulinum toxin, and an enhancing agent that facilitates absorption of the neurotoxin through the skin of the patient and does not eliminate the bioactivity associated with the neurotoxin. The pharmaceutical compositions are topically applied on a patient, and may be provided in a transdermal patch.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: April 27, 2010
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Clostridial toxin derivatives and methods for treating pain
    Patent number: 7704512
    Abstract: Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or fragment or derivative thereof, attached to a targeting moiety, wherein the targeting moiety is selected from a group consisting of transmission compounds which can be released from neurons upon the transmission of pain signals by the neurons, and compounds substantially similar to the transmission compounds.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: April 27, 2010
    Assignee: Allergan, Inc.
    Inventor: Stephen Donovan
  • Combined fence and gate
    Patent number: D734496
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: July 14, 2015
    Inventor: Stephen Donovan