Patents by Inventor Stephen E. Gray

Stephen E. Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amphotericin B derivatives with improved therapeutic index
    Patent number: 11970512
    Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: April 30, 2024
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam
  • Optical Stack, Optical System, Optical Detection System, and Optical Imaging System
    Publication number: 20240125704
    Abstract: An optical stack for sensing a presence of an analyte is provided. The optical stack includes a sensor material. The sensor material includes a first optical response including a first optical property having a second value in response to an excitation signal including the first optical property having a first value different from the second value. The first optical response includes a second optical property sensitive to the presence of the analyte. The optical stack includes a first optical film disposed proximate the sensor material and includes a third optical property having respective third and fourth values in response to the respective first and second values of the first optical property. The third value is different from the fourth value by at least a factor of 2.
    Type: Application
    Filed: February 3, 2022
    Publication date: April 18, 2024
    Inventors: Jessica E. Demay, John A. Wheatley, William J. Gray, Johah Shaver, Neil Percy, Aaron M. Marcella, Stephen M. Kennedy, Zhaohui Yang, Bharat R. Acharya
  • Method and system for transfer of employee stock options
    Patent number: 7769666
    Abstract: A plurality of option value prices are determined for employee stock options. An average stock price corresponding to a particular one of the plurality of option value prices is determined. The employee stock option is exchanged for the value. The terms of the employee stock option are amended and the option is transferred to a third party in exchange for a value. The third party hedges the amended options.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: August 3, 2010
    Assignee: J.P. Morgan Chase Bank
    Inventors: Allen R. Friedman, Stephen E. Gray, Stephen L. Roti, David A. Seaman, Benjamin B. Lopata, Kelly Cesare
  • Method and system for transfer of employee stock options
    Patent number: 7765144
    Abstract: A plurality of option value prices are determined for employee stock options and provided to employees during a first part of a decision period. A stock price corresponding to a particular one of the plurality of option value prices is determined and provided to the employees during the second part of the decision period. A plurality of transfer periods for employee stock options are provided, with a plurality of decision periods during each transfer period. An option value determined by an option value pricing formula is provided during each decision period.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: July 27, 2010
    Assignee: JP Morgan Chase Bank
    Inventors: Stephen E. Gray, Stephen L. Roti, David A. Seaman
  • Method and system for transfer of employee stock options
    Publication number: 20040267656
    Abstract: A plurality of option value prices are determined for employee stock options. An average stock price corresponding to a particular one of the plurality of option value prices is determined. The employee stock option is exchanged for the value. The terms of the employee stock option are amended and the option is transferred to a third party in exchange for a value. The third party hedges the amended options.
    Type: Application
    Filed: September 17, 2003
    Publication date: December 30, 2004
    Inventors: Allen R. Friedman, Stephen E. Gray, Benjamin B. Lopata, Stephen L. Roti, David A. Seaman, Kelly Cesare