Patents by Inventor Stephen Eastham

Stephen Eastham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of methyl methacrylate
    Patent number: 11981951
    Abstract: The present invention relates to a process for the production of methyl methacrylate. The process of the present invention comprises the steps of: a) providing a microorganism in a fermentation medium, under conditions which said microorganism will produce a C3-C12 methacrylate ester; b) providing an organic phase in contact with the fermentation medium, said organic phase including C3-C12 methacrylate ester in a higher concentration than that in the fermentation medium; c) removing organic phase containing the said C3-C12 methacrylate ester from contact with the fermentation medium; and d) transesterifying the removed C3-C12 methacrylate ester with methanol, optionally after separation from the organic phase, to produce methyl methacrylate.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: May 14, 2024
    Assignee: Mitsubishi Chemical UK Limited
    Inventors: Graham Ronald Eastham, Zoe Bethany Clare Disley, David William Johnson, Gill Stephens, Mark Waugh
  • Process for and intermediates in the preparation of canfosfamide and its salts
    Patent number: 8334266
    Abstract: A process for and intermediates in the preparation of canfosfamide and its salts. Some of the intermediates have anticancer activity.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: December 18, 2012
    Assignee: Telik, Inc.
    Inventors: William A. Boulanger, Steven J. Collier, Stephen A. Eastham, Dennis L. Edie, Ronan Y. Guevel, Pedro E. Hernandez Abad, R. Jason Herr, Hans J. Kjaersgaard, Harold Meckler, Robert E. Polomski, Steven R. Schow, Pavel E. Zhichkin
  • PROCESS FOR AND INTERMEDIATES IN THE PREPARATION OF CANFOSFAMIDE AND ITS SALTS
    Publication number: 20120238772
    Abstract: A process for and intermediates in the preparation of canfosfamide and its salts. Some of the intermediates have anticancer activity.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 20, 2012
    Inventors: William A. Boulanger, Steven J. Collier, Stephen A. Eastham, Dennis L. Edie, Ronan Y. Guevel, Pedro E. Hernández Abad, R. Jason Herr, Hans J. Kjaersgaard, Harold Meckler, Robert E. Polomski, Steven R. Schow, Pavel E. Zhichkin
  • Process for and intermediates in the preparation of canfosfamide and its salts
    Publication number: 20060135409
    Abstract: A process for and intermediates in the preparation of canfosfamide and its salts. Some of the intermediates have anticancer activity.
    Type: Application
    Filed: December 21, 2004
    Publication date: June 22, 2006
    Inventors: William Boulanger, Steven Collier, Stephen Eastham, Dennis Edie, Ronan Guevel, Pedro Abad, R. Herr, Hans Kjaersgaard, Harold Meckler, Robert Polomski, Steven Schow, Pavel Zhichkin
  • Catalytic hydrogenation of nitriles to produce capsaicinoid derivatives and amine compounds, and methods for purifying and obtaining the polymorphs thereof
    Publication number: 20060047171
    Abstract: Processes for preparing an amine compound by catalytically hydrogenating a precursor nitrile compound. In a particular aspect, the present hydrogenation process occurs in a dipolar organic solvent in the presence of a palladium/carbon catalyst and a strong anhydrous protic acid. In a further aspect, the preferred embodiment relates to a process for deprotecting a compound to produce an amine compound. In yet a further aspect, the preferred embodiment relates to amine products produced by the present processes. These amine products may be used for a variety of purposes.
    Type: Application
    Filed: August 27, 2004
    Publication date: March 2, 2006
    Inventors: Harold Meckler, Karl Popp, Bingidimi Mobele, Paul Isbester, Bruce Elder, Paul Vogt, Benjamin Littler, Stephen Eastham, David Reed, Luckner Ulysse, Michael Uttley