Abstract: Systems are disclosed for facilitating intranasal treatment of a patient's sphenopalatine/pterygopalatine recess. Likewise the instant system is effective for addressing acute pain conditions, and is refined enough to be performed by physician's assistants, nurses, and other well-trained practitioners. Apparatus involved includes a sheath hub, a catheter hub, an arresting element, and an engagement element in embodiments. Engagement between the arresting element and the engagement element prevents rotation of the sheath hub with respect to the catheter hub.

Abstract: Systems are disclosed for facilitating intranasal treatment of a patient's sphenopalatine/pterygopalatine recess. Likewise the instant system is effective for addressing acute pain conditions, and is refined enough to be performed by physician's assistants, nurses, and other well-trained practitioners. Apparatus involved includes a sheath hub, a catheter hub, an arresting element, and an engagement element in embodiments. Engagement between the arresting element and the engagement element prevents rotation of the sheath hub with respect to the catheter hub.

Abstract: Neuro-modulation of the SPG is achieved by direct delivery of medication that includes a CGRP receptor antagonist using a trans-nasal drug delivery device with delivery features that may include an ergonomic grip, directional control and indicators, or radiopaque portions.

Abstract: The invention provides a system and method for pain treatment in which a medication is delivered with good localization to the SPG and to the maxillary division of the trigeminal nerve—known a V2. A treating physician uses a drug delivery device to insert a delivery catheter into nostril of a patient lying supine and orient the catheter with respect to the SPG and V2. The physician operates a mechanism on the catheter to express the medication and allows for gravity-influenced transport to bring the medication to the SPG and V2.

Abstract: An apparatus, system, and method are disclosed for facilitating intranasal administration of a medication to a patient's sphenopalatine/pterygopalatine recess. The apparatus includes a catheter having a lumen disposed therethrough, the catheter comprising an insertion end and a manipulation end, the insertion end having an intrinsic curvature with respect to a longitudinal axis of the catheter such that the insertion end of the catheter lies in a first plane and the manipulation end lies in a second plane, wherein the catheter smoothly transitions between the first plane and the second plane, the intrinsic curvature conforming to a patients nasal anatomy such that the catheter may be inserted into a sphenopalatine/pterygopalatine recess. The apparatus also includes a straightening member configured to removably engage the catheter. The straightening member straightens the intrinsic curvature such that the first plane and the second plane are aligned when the catheter is engaged by the straightening member.

Abstract: Systems are disclosed for facilitating intranasal treatment of a patient's sphenopalatine/pterygopalatine recess. Likewise the instant system is effective for addressing acute pain conditions, and is refined enough to be performed by physician's assistants, nurses, and other well-trained practitioners. Apparatus involved includes a sheath hub, a catheter hub, an arresting element, and an engagement element in embodiments. Engagement between the arresting element and the engagement element prevents rotation of the sheath hub with respect to the catheter hub.

Abstract: An apparatus, system, and method are disclosed for facilitating intranasal administration of a medication to a patient's sphenopalatine/pterygopalatine recess. The apparatus includes a catheter having a lumen disposed therethrough, the catheter comprising an insertion end and a manipulation end, the insertion end having an intrinsic curvature with respect to a longitudinal axis of the catheter such that the insertion end of the catheter lies in a first plane and the manipulation end lies in a second plane, wherein the catheter smoothly transitions between the first plane and the second plane, the intrinsic curvature conforming to a patients nasal anatomy such that the catheter may be inserted into a sphenopalatine/pterygopalatine recess. The apparatus also includes a straightening member configured to removably engage the catheter. The straightening member straightens the intrinsic curvature such that the first plane and the second plane are aligned when the catheter is engaged by the straightening member.