Patents by Inventor Stephen Eric NYBO

Stephen Eric NYBO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified host organism for expressing an anthracyclinone analogue, method associated therewith, and synthetic nucleic acids
    Patent number: 10980817
    Abstract: Disclosed is a genetically modified host organism for expressing an anthracyclinone analogue. The genetically modified host organism comprises (i) synthetic nucleic acids; (ii) a biosynthetic pathway encoded by the synthetic nucleic acids, the (ii) biosynthetic pathway comprising a ketosynthase alpha, a ketosynthase beta/chain-length factor, an acyl carrier protein, a 3-oxoacyl-ACP synthase, a propionyl-CoA acyltransferase, a 9-ketoreductase, an aromatase/cyclase, and a second/third-ring cyclase; and (iii) a promoter positioned upstream of and operatively associated with the (ii) biosynthetic pathway. A method and corresponding synthetic nucleic acids are also disclosed.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: April 20, 2021
    Inventor: Stephen Eric Nybo
  • GENETICALLY MODIFIED HOST ORGANISM FOR EXPRESSING AN ANTHRACYCLINONE ANALOGUE, METHOD ASSOCIATED THEREWITH, AND SYNTHETIC NUCLEIC ACIDS
    Publication number: 20180369256
    Abstract: Disclosed is a genetically modified host organism for expressing an anthracyclinone analogue. The genetically modified host organism comprises (i) synthetic nucleic acids; (ii) a biosynthetic pathway encoded by the synthetic nucleic acids, the (ii) biosynthetic pathway comprising a ketosynthase alpha, a ketosynthase beta/chain-length factor, an acyl carrier protein, a 3-oxoacyl-ACP synthase, a propionyl-CoA acyltransferase, a 9-ketoreductase, an aromatase/cyclase, and a second/third-ring cyclase; and (iii) a promoter positioned upstream of and operatively associated with the (ii) biosynthetic pathway. A method and corresponding synthetic nucleic acids are also disclosed.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 27, 2018
    Inventor: Stephen Eric NYBO