Patents by Inventor Stephen Frey

Stephen Frey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132578
    Abstract: The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies may be characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.
    Type: Application
    Filed: August 18, 2023
    Publication date: April 25, 2024
    Inventors: Po-Ying Chan-Hui, Katherine Doores, Michael Huber, Stephen Kaminsky, Steven Frey, Ole Olsen, Jennifer Mitcham, Matthew Moyle, Sanjay K. Phogat, Dennis R. Burton, Laura Majorie Walker, Pascal Raymond Georges Poignard, Wayne Koff, Melissa Danielle De Jean De St. Marcel Simek-Lemos
  • Publication number: 20220129909
    Abstract: A method, a device, and a non-transitory storage medium provide a vessel detention prevention and risk assessment service. The service may determine whether a vessel has a detention risk upon arrival at a next destination. The service may initiate actions to be taken to minimize or prevent the detention risk before arrival. The service may also calculate an overall risk of the vessel based on registry data, port state control data, and/or class society data.
    Type: Application
    Filed: October 22, 2020
    Publication date: April 28, 2022
    Inventors: Alfonso Castillero, Stephen Frey
  • Publication number: 20110092803
    Abstract: The invention relates generally to apparatus and devices for neuronavigation. A non-invasive dental based fiducial array is disclosed. The fiducial array has a base support member, one or more removable and repositionable marker bases supported by the base support member and a stopper spaced from and supported by the base support member that engages a part of the head of a patient or an animal and cooperates with the base support member to immobilize the fiducial array relative to a location of the head, such as maxillary teeth. An anchoring site is formed on the base support member to accept a custom made dental impression to precisely position the base support member relative to the location of the head.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 21, 2011
    Inventors: Brian Hynes, Roch M. Comeau, Stephen Frey