Patents by Inventor Stephen Gatto

Stephen Gatto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12357600
    Abstract: Formulations comprising particular free amino acids useful for promoting hydration and/or intestinal barrier function in a subject in need thereof are described herein. Such formulations and methods using same are useful for promoting hydration and/or intestinal barrier function in a subject in need thereof. Such subjects may be healthy, but in need of a formulation that promotes rapid hydration (e.g., within 15-90 minutes post-administration) or promotes intestinal barrier function; or such subjects may be afflicted by a disorder or disease associated with dehydration or impaired intestinal barrier function, respectively.
    Type: Grant
    Filed: December 30, 2022
    Date of Patent: July 15, 2025
    Assignees: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED, AMILYFE, LLC.
    Inventors: Sadasivan Vidyasagar, Astrid Grosche, Xiaodong Xu, Shanshan Lin, Samuel Cheuvront, Robert Kenefick, Stephen Gatto
  • Patent number: 12109191
    Abstract: The subject invention provides compositions and methods for inhibiting the growth and/or proliferation of cancer cells. The subject invention also provides methods for treating cancer in a subject in need of such treatment by administering a composition described herein. The subject invention can be used to inhibit cancer cell growth by exposing the cells to a composition. The subject invention further provides cancer treatments that may be used in combination with surgery, chemotherapy, and/or radiation therapy.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: October 8, 2024
    Assignees: AmiLyfe, LLC, University of Florida Research Foundation, Incorporated
    Inventors: Sadasivan Vidyasagar, Reshu Gupta, Stephen Gatto
  • Publication number: 20230210798
    Abstract: Amino acid formulations useful for treating diarrhea in a subject in need thereof are described herein. Such amino acid formulations and methods comprising administering same to a subject are useful for treating diarrhea, particularly diarrhea caused by or associated with bacterial infections wherein secretagogue-stimulated anion secretion from the intestinal crypt contributes to at least one symptom of diarrhea in the subject. Use of these amino acid formulations for the treatment of diarrhea in general or diarrhea associated with secretagogue-stimulated anion secretion from the intestinal crypt are encompassed herein, as are their use in the preparation of a medicament for the treatment of diarrhea in general or diarrhea associated with secretagogue-stimulated anion secretion from the intestinal crypt.
    Type: Application
    Filed: June 2, 2021
    Publication date: July 6, 2023
    Inventors: Sadasivan VIDYASAGAR, Astrid GROSCHE, Xiaodong XU, Shanshan LIN, Stephen GATTO, Robert KENEFICK, Samuel CHEUVRONT
  • Publication number: 20230149335
    Abstract: Formulations comprising particular free amino acids useful for promoting hydration and/or intestinal barrier function in a subject in need thereof are described herein. Such formulations and methods using same are useful for promoting hydration and/or intestinal barrier function in a subject in need thereof. Such subjects may be healthy, but in need of a formulation that promotes rapid hydration (e.g., within 15-90 minutes post-administration) or promotes intestinal barrier function; or such subjects may be afflicted by a disorder or disease associated with dehydration or impaired intestinal barrier function, respectively.
    Type: Application
    Filed: December 30, 2022
    Publication date: May 18, 2023
    Inventors: Sadasivan VIDYASAGAR, Astrid GROSCHE, Xiaodong XU, Shanshan LIN, Samuel CHEUVRONT, Robert KENEFICK, Stephen GATTO
  • Patent number: 11576884
    Abstract: The present disclosure provides compositions and methods for promoting stem cell and/or progenitor cell proliferation and/or differentiation. The provided compositions may be useful in treating a disease or condition that is related to mucosal barrier function, e.g., wound healing, treating skin conditions (e.g., atopic dermatitis, psoriasis, bed sores, or condition related to the aging of skin), treating a lung disorders (e.g., asthma), a condition related to improving mucosal barrier function, and/or treating injury to GI mucosa in a subject in need thereof. The present disclosure also provides methods for promoting the proliferation and/or differentiation of stem cells and/or the progenitor cells in a subject in need of such treatment by administering a composition. The ability to stimulate the proliferation and/or differentiation of stem cells and/or the progenitor cells in vivo, ex vivo and/or in vitro provides tremendous benefit.
    Type: Grant
    Filed: October 4, 2017
    Date of Patent: February 14, 2023
    Assignees: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., ENTRINSIC, LLC
    Inventors: Sadasivan Vidyasagar, Reshu Gupta, Liangjie Yin, Astrid Grosche, Paul Gerson Okunieff, Stephen Gatto, Daniel Dennison
  • Publication number: 20210283081
    Abstract: The present disclosure provides compositions and methods for promoting stem cell and/or progenitor cell proliferation and/or differentiation. The provided compositions may be useful in treating a disease or condition that is related to mucosal barrier function, e.g., wound healing, treating skin conditions (e.g., atopic dermatitis, psoriasis, bed sores, or condition related to the aging of skin), treating a lung disorders (e.g., asthma), a condition related to improving mucosal barrier function, and/or treating injury to GI mucosa in a subject in need thereof. The present disclosure also provides methods for promoting the proliferation and/or differentiation of stem cells and/or the progenitor cells in a subject in need of such treatment by administering a composition. The ability to stimulate the proliferation and/or differentiation of stem cells and/or the progenitor cells in vivo, ex vivo and/or in vitro provides tremendous benefit.
    Type: Application
    Filed: October 4, 2017
    Publication date: September 16, 2021
    Applicants: University of Florida Research Foundation Incorporated, Entrinsic Health Solutions, Inc.
    Inventors: Sadasivan Vidyasagar, Reshu Gupta, Lianjie Yin, Astrid Grosche, Paul Gerson Okunieff, Stephen Gatto, Daniel Dennison
  • Publication number: 20200323820
    Abstract: The subject invention provides compositions and methods for inhibiting the growth and/or proliferation of cancer cells. The subject invention also provides methods for treating cancer in a subject in need of such treatment by administering a composition described herein. The subject invention can be used to inhibit cancer cell growth by exposing the cells to a composition. The subject invention further provides cancer treatments that may be used in combination with surgery, chemotherapy, and/or radiation therapy.
    Type: Application
    Filed: October 2, 2018
    Publication date: October 15, 2020
    Inventors: Sadasivan Vidyasagar, Reshu Gupta, Stephen Gatto