Patents by Inventor Stephen George Dann

Stephen George Dann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY
    Publication number: 20230321042
    Abstract: This invention relates to combination therapies for use in treating cancer, comprising a cyclin dependent kinase 2 (CDK2) inhibitor of Formula (I), as further described herein, and a cyclin dependent kinase 4/6 (CDK4/6) inhibitor, optionally in further combination with an additional anti-cancer agent=.
    Type: Application
    Filed: July 16, 2021
    Publication date: October 12, 2023
    Applicant: PFIZER INC.
    Inventors: Stephen George DANN, Nichol Lee Goodman MILLER, Todd Lee VANARSDALE
  • CO-TREATMENT WITH CDK4/6 AND CDK2 INHIBITORS TO SUPPRESS TUMOR ADAPTATION TO CDK2 INHIBITORS
    Publication number: 20230158034
    Abstract: The invention provides a method for treating a disease or disorder, and preferably cancer, comprising administering to a subject in need thereof a therapeutically effective amount of a CDK2 inhibitor, and a therapeutically effective amount of a CDK4/6 inhibitor, wherein the CDK4/6 inhibitor prevents rebound phosphorylation mediated by CDK4 and/or CDK6 in response to the inhibition of CDK2.
    Type: Application
    Filed: April 7, 2021
    Publication date: May 25, 2023
    Applicants: Pfizer Inc., The Regents of the University of Colorado, a body corporate
    Inventors: Mansi Arora, Stephen George Dann, Nichol Lee Goodman Miller, Sabrina Spencer, Todd Lee VanArsdale
  • COMBINATION THERAPIES USING CDK INHIBITORS
    Publication number: 20230053328
    Abstract: This invention relates to a method for treating cancer by administering a CDK4/6 inhibitor or CDK2/4/6 inhibitor in combination with a 4-1BB agonist and/or an OX40 agonist to a subject in need thereof.
    Type: Application
    Filed: May 21, 2020
    Publication date: February 16, 2023
    Applicant: Pfizer Inc.
    Inventors: Stephen George Dann, Cecilia Marianne Oderup, Shahram Salek-Ardakani
  • COMBINATION THERAPIES USING CDK INHIBITORS
    Publication number: 20220241412
    Abstract: This invention relates to a method for treating cancer by administering a CDK4/6 or a CDK2/4/6 inhibitor in combination with a PD-1 axis binding antagonist, and optionally an OX40 agonist and/or a 4-1BB agonist to a subject in need thereof.
    Type: Application
    Filed: May 20, 2020
    Publication date: August 4, 2022
    Inventors: Stephen George Dann, Cecilia Marianne Oderup, Shahram Salek-Ardakani
  • COMBINATION THERAPIES USING CDK INHIBITORS
    Publication number: 20220235141
    Abstract: This invention relates to a method for treating cancer by administering a CDK4/6 inhibitor or CDK2/4/6 inhibitor in combination with a 4-1BB agonist and/or an OX40 agonist to a subject in need thereof.
    Type: Application
    Filed: May 21, 2020
    Publication date: July 28, 2022
    Applicant: Pfizer Inc.
    Inventors: Stephen George Dann, Cecilia Marianne Oderup, Shahram Salek-Ardakani