Patents by Inventor Stephen Gordon Will

Stephen Gordon Will has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Light Emission Modifiers and Their Uses in Nucleic Acid Detection, Amplification and Analysis
    Publication number: 20100015629
    Abstract: The present invention relates to methods and reagents for modifying the emission of light from labeled nucleic acids for the purpose of real time detection, analysis, and quantitation of nucleic acid sequences, e.g., using singly labeled probes. These methods and reagents exploit advantageous properties of thiazine dyes and diazine dyes. Furthermore, the use of these light emission modifiers in background reduction, nucleic acid duplex stabilization and other uses is also described. Related kits, reaction mixtures and integrated systems are described.
    Type: Application
    Filed: September 1, 2009
    Publication date: January 21, 2010
    Applicant: ROCHE MOLECULAR SYSTEM, INC.
    Inventors: Amar P. Gupta, Stephen Gordon Will
  • Probes and Methods for Hepatitis C Virus Typing Using Single Probe Analysis
    Publication number: 20090098532
    Abstract: This invention provides compositions and methods for HCV typing, e.g., genotyping and/or subtyping. The compositions and methods of the invention can be used to assign an HCV isolate to one of at least five HCV genotypes (for example, selected from genotypes 1, 2, 3, 4, 5 or 6), or assign an HCV isolate to one of at least six subtypes (for example, selected from subtypes 1a/b/c, 2a/c, 2b, 3a, 4a, 5a or 6a), where the methods of the invention use only a single typing probe to make the HCV type assignment.
    Type: Application
    Filed: November 11, 2008
    Publication date: April 16, 2009
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Amar P. Gupta, Stephen Gordon Will
  • Detectable labeled nucleoside analogs and methods of use thereof
    Patent number: 7501504
    Abstract: The invention relates to detectable labels useful for detection of nucleotide sequences. Specifically, the invention relates to labeled-imidazole-PEG compounds, such as nucleosides, nucleotides, and nucleic acids incorporating such compounds, and methods utilizing such compounds. The invention further relates to kits comprising labeled imidazole-PEG compounds.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: March 10, 2009
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Veeraiah Bodepudi, Amar Gupta, Stephen Gordon Will
  • Probes and methods for hepatitis C virus typing using single probe analysis
    Patent number: 7465561
    Abstract: This invention provides compositions and methods for HCV typing, e.g., genotyping and/or subtyping. The compositions and methods of the invention can be used to assign an HCV isolate to one of at least five HCV genotypes (for example, selected from genotypes 1, 2, 3, 4, 5 or 6), or assign an HCV isolate to one of at least six subtypes (for example, selected from subtypes 1a/b/c, 2a/c, 2b, 3a, 4a, 5a or 6a), where the methods of the invention use only a single typing probe to make the HCV type assignment.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: December 16, 2008
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Amar P. Gupta, Stephen Gordon Will
  • Detectable labeled nucleoside analogs and methods of use thereof
    Patent number: 7456266
    Abstract: The invention relates to detectable labels useful for detection of nucleotide sequences. Specifically, the invention relates to labeled-imidazole-PEG compounds, such as nucleosides, nucleotides, and nucleic acids incorporating such compounds, and methods utilizing such compounds. The invention further relates to kits comprising labeled imidazole-PEG compounds.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: November 25, 2008
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Veeraiah Bodepudi, Amar Gupta, Stephen Gordon Will
  • Modified nucleic acid amplification primers
    Patent number: 6001611
    Abstract: The present invention provides modified primers for use in the amplification of a nucleic acid sequence. Amplifications carried out using the modified primers result in less non-specific amplification product, in particular, primer dimer, and a concomitant greater yield of the intended amplification product compared to amplifications carried out using unmodified primers.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: December 14, 1999
    Assignee: Roche Molecular Systems, Inc.
    Inventor: Stephen Gordon Will