Abstract: Methods for imaging beta cells in pancreatic tissue using radioisotopes of manganese, which may be referred to as radiomanganese, are described. Example radioisotopes of manganese include Mn-52g, Mn-52m, and Mn-51. As one example, radiomanganese can be used to image pancreatic beta cells, in which radiomanganese shows a preferential uptake. This provides for applications such as quantifying beta cell mass (e.g., functional beta cell mass), assessing transplant viability, and monitoring the efficacy of drug treatments. A pharmacological agent can be administered to modulate the uptake of divalent metals by the pancreatic beta cells, which can be correlated to a modulated uptake of radiomanganese to estimate pancreatic beta cell mass, function, or both.

Abstract: A phantom for a nuclear imaging system is provided. In particular, systems and method are provided for a phantom including a pattern plate having a plurality of passages and a plurality of channels sequentially interconnecting each of the plurality of cylindrical cavities.

Abstract: The inactivity alarm has programmable interval timing electronic circuitry, including a reset button. Audible alert electronic circuitry is actuated by timeout of the programmable timing interval to provide successively louder audible signals if the reset button has not been pressed within the timing interval. In another embodiment, the system is included in an electronic telephone. The telephone sends a signal responsive to a predetermined user actuation of the phone. A first timer is resettable by the telephone signal to prevent timeout. The audible alert is activated by timeout of the first timer. A programmed telephone number dialing circuit and second timer are provided. The second timer is resettable by the telephone signal to prevent timeout of the second timer. The programmed telephone number dialing circuitry is activated on timeout of the second timer to dial at least one stored telephone number. Alternatively, timer functions are implemented in a Central Office.