Patents by Inventor Stephen Gruber

Stephen Gruber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APC mutation associated with familial colorectal cancer in Ashkenazi Jews
    Patent number: 6013461
    Abstract: During routine screening of a patient with a family history of colorectal cancer for truncating APC mutations, a novel missense mutation was identified. Upon further evaluation, it was found that 6% of Ashkenazi Jews carry this mutation, and that it was present in .sup..about. 20% of Ashkenazis with a family history of CRC. Probes, methods, and kits for identifying individuals affected with this missense mutation are provided.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: January 11, 2000
    Assignee: The Johns Hopkins University
    Inventors: Steve Laken, Stephen Gruber, Gloria Petersen, Kenneth Kinzler, Bert Vogelstein
  • APC mutation associated with familial colorectal cancer in Ashkenazi jews
    Patent number: 5879890
    Abstract: During routine screening of a patient with a family history of colorectal cancer for truncating APC mutations, a novel missense mutation was identified. Upon further evaluation, it was found that 6% of Ashkenazi Jews carry this mutation, and that it was present in .sup..about. 20% of Ashkenazis with a family history of CRC. Probes, methods, and kits for identifying individuals affected with this missense mutation are provided.
    Type: Grant
    Filed: January 31, 1997
    Date of Patent: March 9, 1999
    Assignee: The Johns Hopkins University
    Inventors: Steve Laken, Stephen Gruber, Gloria Petersen, Kenneth Kinzler, Bert Vogelstein