Patents by Inventor Stephen H. Buck

Stephen H. Buck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neurokinin A antagonists
    Patent number: 5830863
    Abstract: Antagonists of neurokinin A which are derivatives of naturally occurring neurokinin A in which the amide bond connecting the two amino acids on the carboxy terminal end is modified are described. The antagonism is confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions in which neurokinin A is implicated is also described.
    Type: Grant
    Filed: December 13, 1996
    Date of Patent: November 3, 1998
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Stephen H. Buck, Scott L. Harbeson, John L. Krstenansky, Chester F. Hassman, III, James R. McCarthy
  • Cyclic neurokinin A antagonists
    Patent number: 5731286
    Abstract: Antagonists of neurokinin A which are derivatives of naturally occurring neurokinin A in which the amide bond connecting the two amino acids on the carboxy terminal end is modified are described. The antagonism is confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions in which neurokinin A is implicated is also described.
    Type: Grant
    Filed: March 5, 1997
    Date of Patent: March 24, 1998
    Assignee: Merrell Pharmaceuticals, Inc.
    Inventors: Scott L. Harbeson, Stephen H. Buck
  • Cyclic neurokinin A antagonists
    Patent number: 5521156
    Abstract: Antagonists of neurokinin A which are novel cyclic hexapeptide and octapeptide compounds are described. The antagonism is confirmed using conventional competitive binding and biochemical assays as well as conventional physiological tests and the use of these derivatives in a variety of conditions in which neurokinin A is implicated is also described.
    Type: Grant
    Filed: February 3, 1994
    Date of Patent: May 28, 1996
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Thomas J. Owen, Elizabeth M. Kudlacz, Scott L. Harbeson, Stephen H. Buck