Patents by Inventor Stephen H. Spiegelberg

Stephen H. Spiegelberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for making oxidation resistant polymeric material
    Patent number: 10821632
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: November 3, 2020
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • METHODS FOR MAKING OXIDATION RESISTANT POLYMERIC MATERIAL
    Publication number: 20180194042
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Application
    Filed: March 7, 2018
    Publication date: July 12, 2018
    Applicants: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Cross-linking of antioxidant-containing polymers
    Patent number: 9962463
    Abstract: The present invention relates to methods for making cross-linked, oxidatively stable, and highly crystalline polymeric materials. The invention also provides methods of treating irradiation-cross-linked antioxidant-containing polymers and materials used therewith.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: May 8, 2018
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Methods for making oxidation resistant polymeric material
    Patent number: 9943993
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: April 17, 2018
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • METHODS FOR MAKING OXIDATION RESISTANT POLYMERIC MATERIAL
    Publication number: 20170259467
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Application
    Filed: May 16, 2017
    Publication date: September 14, 2017
    Applicants: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. MURATOGLU, Stephen H. SPIEGELBERG
  • Methods for making oxidation resistant polymeric material
    Patent number: 9688004
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: June 27, 2017
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Methods for making oxidation resistant polymeric material
    Patent number: 9561306
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion, post-doping annealing, and materials used therein.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: February 7, 2017
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • CROSS-LINKING OF ANTIOXIDANT-CONTAINING POLYMERS
    Publication number: 20160296661
    Abstract: The present invention relates to methods for making cross-linked, oxidatively stable, and highly crystalline polymeric materials. The invention also provides methods of treating irradiation-cross-linked antioxidant-containing polymers and materials used therewith.
    Type: Application
    Filed: June 16, 2016
    Publication date: October 13, 2016
    Applicants: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. MURATOGLU, Stephen H. SPIEGELBERG
  • Cross-linking of antioxidant-containing polymers
    Patent number: 9441081
    Abstract: The present invention relates to methods for making cross-linked, oxidatively stable, and highly crystalline polymeric materials. The invention also provides methods of treating irradiation-cross-linked antioxidant-containing polymers and materials used therewith.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: September 13, 2016
    Assignees: The General Hospital Corp., Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Tough hydrogels
    Patent number: 9394384
    Abstract: The invention provides fabricated tough hydrogels, hydrogel-containing compositions, and methods of making the same. The invention also provides methods of implanting or administering the tough hydrogels, or the hydrogel-containing compositions to treat a subject in need. Methods of cross-linking pre-solidified or pre-gelled hydrogel particles and making crosslinked tough hydrogels, and crosslinked tough hydrogel-containing compositions also are disclosed herein.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: July 19, 2016
    Assignee: The General Hospital Corporation
    Inventors: Orhun K. Muratoglu, Jeeyoung Choi, Hatice Bodugoz-Senturk, Gavin J. C. Braithwaite, Stephen H. Spiegelberg
  • Methods for making oxidation resistant polymeric material
    Patent number: 9370878
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 21, 2016
    Assignees: The General Hospital Corp., Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Mosaicplasty constructs
    Patent number: 9289302
    Abstract: Various embodiments of mosaicplasty constructs and methods for implanting the constructs into anatomical structures. The mosaicplasty constructs may be formed from artificial materials and may include a hard articulating portion and a relatively softer elastic, support portion. The mosaicplasty constructs may include bone ingrowth materials to facilitate ingrowth of bone and other tissues into the construct. The mosaicplasty constructs may also be at least partially formed of hydrogel materials.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: March 22, 2016
    Assignee: Zimmer, Inc.
    Inventors: Brian H. Thomas, Steven J. Charlebois, Donald Yakimicki, James Mason, Stephen H. Spiegelberg, Gavin Braithwaite, Gareth McKinley, Orhun Muratoglu
  • Methods for making oxidation resistant polymeric material
    Patent number: 8968628
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: March 3, 2015
    Assignees: The General Hospital Corp., Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Methods for making oxidation resistant polymeric material
    Patent number: 8888859
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: November 18, 2014
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Methods for making oxidation resistant polymeric material
    Patent number: 8865043
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion, post-doping annealing, and materials used therein.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: October 21, 2014
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • METHODS FOR MAKING OXIDATION RESISTANT POLYMERIC MATERIAL
    Publication number: 20140275318
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Application
    Filed: May 27, 2014
    Publication date: September 18, 2014
    Applicants: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. MURATOGLU, Stephen H. Spiegelberg
  • METHODS FOR MAKING OXIDATION RESISTANT POLYMERIC MATERIAL
    Publication number: 20140183794
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion, post-doping annealing, and materials used therein.
    Type: Application
    Filed: March 10, 2014
    Publication date: July 3, 2014
    Applicants: Cambridge Polymer Group, Inc., The General Hospital Corporation
    Inventors: Orhun K. MURATOGLU, Stephen H. Spiegelberg
  • Methods for making oxidation resistant polymeric material
    Patent number: 8728379
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: May 20, 2014
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • Methods for making oxidation resistant polymeric material
    Patent number: 8530057
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: September 10, 2013
    Assignees: The General Hospital Corporation, Cambridge Polymer Group, Inc.
    Inventors: Orhun K. Muratoglu, Stephen H. Spiegelberg
  • METHODS FOR MAKING OXIDATION RESISTANT POLYMERIC MATERIAL
    Publication number: 20130062817
    Abstract: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion, post-doping annealing, and materials used therein.
    Type: Application
    Filed: September 7, 2012
    Publication date: March 14, 2013
    Applicants: Cambridge Polymer Group, Inc., The General Hospital Corporation
    Inventors: Orhun K. MURATOGLU, Stephen H. Spiegelberg