Abstract: A balance board system may include a balance board, a phone that is mounted to the balance board, and a display device on which a virtual environment may be displayed. The virtual environment can include a representation of the balance board that is oriented based on the balance board's orientation as detected by the phone. The virtual environment can enable a user to learn and practice tricks or other activities on a balance board. A phone mount can be used to mount the phone to the balance board. By mounting the phone to the balance board, software on the phone can be used to detect and monitor the balance board's movement to thereby assist the user in improving his or her balance or learning various tricks, movements or techniques. The software on the phone can also allow the user to generate inputs for various games that can be portrayed in the virtual environment.

Abstract: The present disclosure relates to an alkylated graphene oxide membrane comprising a plurality of graphene oxide layers, each graphene oxide layer including at least one graphene oxide sheet covalently coupled to a chemical spacer, the chemical spacer being of Formula I: The present disclosure also relates to a filtration apparatus comprising an alkylated graphene oxide membrane disposed on a support substrate.

Abstract: Inflatables can have one or more flat segments that are configured to form one or more bends. The flat segments of the inflatables could be formed using any technique such as drop stitch. One or more bends may be maintained in one or more flat segments of an inflatable such as to create a ladder and a slide. A variety of bend maintaining components can be used to maintain the one or more bends.

Abstract: A method of manufacturing an elevator of a medical device comprises using an additive manufacturing method, forming a pivot portion at a proximal end of the elevator. The pivot portion tapers proximally such that a proximalmost end of the elevator is thinner than more distal portions of the pivot portion. The method further comprises using the additive manufacturing method, forming a body of the elevator that is distal to the pivot portion. The elevator body includes a surface configured to contact an instrument inserted in a working channel of the medical device.

Abstract: Described herein include compositions and methods that can be useful for inhibiting activity of Tfh cells, B-cells, germinal centers, extrafollicular T and B-cells, and/or ectopic follicular structures; and/or in treating diseases such as autoimmune diseases.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides a method for identifying a compound of interest by screening libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides a method for identifying a compound of interest by screening libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides methods of synthesizing a molecule comprising a functional moiety which is operatively linked to an encoding oligonucleotide. The methods include providing an initiator compound comprising an initial functional moiety comprising n building blocks, wherein the initial functional moiety comprises at least one reactive group, and is operatively linked to an initial oligonucleotide; reacting the initiator compound with a building block comprising at least one complementary reactive group, under conditions suitable for reaction of the complementary reactive group to form a covalent bond; and reacting the initial oligonucleotide with an incoming oligonucleotide corresponding to the building block in the presence of an enzyme which catalyzes ligation of the initial oligonucleotide and the incoming oligonucleotide, under conditions suitable for ligation of the incoming oligonucleotide and the initial oligonucleotide to form an encoding oligonucleotide.

Abstract: The present invention provides methods of synthesizing libraries of molecules comprising a functional moiety which is operatively linked to an encoding oligonucleotide, wherein the encoding oligonucleotide comprises a capping sequence containing degenerate nucleotides.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides methods of synthesizing libraries of molecules comprising a functional moiety which is operatively linked to an encoding oligonucleotide.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides a method for identifying a compound of interest by screening libraries of molecules which include an encoding oligonucleotide tag.

Abstract: A method of identifying a modulator Nogo function, the method comprising: (i) providing (a) a BACE polypeptide; (b) a Nogo polypeptide; (c) a test agent under conditions that would permit binding of a BACE polypeptide (a) to a Nogo polypeptide (b) in the absence of the test agent (c) wherein said BACE polypeptide (a) is BACE or a variant thereof or a fragment of either thereof capable of binding Nogo; and polypeptide (b) is Nogo or a variant thereof or a fragment of either thereof capable of binding BACE; (ii) monitoring Nogo mediated activity; and (iii) determining thereby whether the test agent is a modulator of Nogo activity. Modulators identified by a method of the invention and use of such modulators in the manufacture of a medicament for the treatment of disorders responsive to the modulation of Nogo activity such as acute neuronal injury.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.

Abstract: The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag.