Abstract: This invention relates to treated geothermal brine compositions containing reduced concentrations of silica, iron, and potassium compared to the untreated brines. Exemplary compositions of the treated brine contain a concentration of silica ranging from about 0 mg/kg to about 15 mg/kg, a concentration of iron ranging from about 0 mg/kg to about 10 mg/kg, and a concentration of potassium ranging from about 300 mg/kg to about 8500 mg/kg. Other exemplary compositions of the treated brines also contain reduced concentrations of elements like rubidium, cesium, and lithium.

Abstract: The present invention is directed to novel retinoid-related orphan receptor gamma (ROR?) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR?.

Abstract: The present invention is directed to novel retinoid-related orphan receptor gamma (ROR?) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR?.

Abstract: A method for the selective precipitation and recovery of manganese from a manganese containing solution, such as a geothermal brine is provided, wherein the geothermal brine is contacted with ammonia, an ammine, or ammonium salt at a pH of greater than about 8.0 to selectively precipitate manganese having a purity of at least about 95%. Also provided are methods for the selective recovery of manganese and zinc from a brine solution.

Abstract: This invention relates to a method for the selective recovery of zinc from geothermal brines, and the subsequent preparation of zinc chloride or zinc sulfate therefrom.

Abstract: A spread spectrum communications method is based on time compression in which a sampled message signal at a first rate is transmitted at a higher sampling rate. Robustness is achieved by dividing the signal into overlapping segments, transmitting each segment fast enough so that the segments no longer overlap. The segments are received and the data signal reconstructed by overlap-adding the segments.

Abstract: The present invention is directed to novel retinoid-related orphan receptor gamma (ROR?) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR?.

Abstract: The present invention is directed to novel retinoid-related orphan receptor gamma (ROR?) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR?.

Abstract: The present invention relates to the use of rotavirus particles for displaying a heterologous protein, alone or in complex with another molecule. The invention further relates to methods that employ these modified rotavirus particles to rapidly determine the structure of the heterologous protein or the complex using cryo-electron microscopy (cryo-EM). The invention also relates to a method of immunising a patient, wherein said method comprises administering to the patient the modified rotavirus particles of the invention.

Abstract: A spread spectrum communications method is based on time compression in which a sampled message signal at a first rate is transmitted at a higher sampling rate. Robustness is achieved by dividing the signal into overlapping segments, transmitting each segment fast enough so that the segments no longer overlap. The segments are received and the data signal reconstructed by overlap-adding the segments.

Abstract: This invention relates to a method for the selective recovery of manganese and zinc from brines that includes the steps of contacting a brine with an ionic liquid in order to selectively extract manganese and zinc from the brine into the ionic liquid; and treating the ionic liquid containing extracted manganese and zinc with an aqueous solution to selectively precipitate manganese, producing a manganese depleted, zinc rich ionic liquid. The method can further include the steps of treating the manganese depleted, zinc rich ionic liquid with an aqueous solution to selectively precipitate zinc.

Abstract: The present invention is directed to novel retinoid-related orphan receptor gamma (ROR?) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR?.

Abstract: This invention relates to a method for the selective recovery of manganese and zinc from geothermal brines that includes the steps of removing silica and iron from the brine, oxidizing the manganese and zinc to form precipitates thereof, recovering the manganese and zinc precipitates, solubilizing the manganese and zinc precipitates, purifying the manganese and zinc, and forming a manganese precipitate, and recovering the zinc by electrochemical means.

Abstract: This invention relates to a method for the preparation of lithium carbonate from lithium chloride containing brines. The method can include a silica removal step, capturing lithium chloride, recovering lithium chloride, supplying lithium chloride to an electrochemical cell and producing lithium hydroxide, contacting the lithium hydroxide with carbon dioxide to produce lithium carbonate.

Abstract: The present invention is directed to novel retinoid-related orphan receptor gamma (ROR?) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR?.

Abstract: The present invention is directed to novel retinoid-related orphan receptor gamma (ROR?) modulators of formula (I), processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR? wherein R1 and R2 are independently selected from the group consisting of H, CF3, halo, C1-3alkyl and C1-3-alkoxy; R3 and R4 are independently selected from the group consisting of H, CF3, halo, CH3 and OCH3; R5 is selected from the group consisting of H, CF3, halo, OH, CH2OH, C1-4alkyl, CH2-cyclopropyl and C1-4alkoxy, wherein C1-4alkyl and C1-4alkoxy, may be optionally substituted with one or two OH substituents; R6 is selected from the group consisting of C3-5alkyl and —CH2—C3-4cycloalkyl; R7 is selected from the group consisting of R8 is selected from the group consisting of C1-3alkyl, C1-3alkoxy, CH2CN, CH2OH, OH, CN and halo; R9 is the group —(CHR10)s—(X)t—(CHR10)u—R11; each R10 is independently

Abstract: This invention relates to a method for the preparation of lithium carbonate from lithium chloride containing brines. The method can include a silica removal step, capturing lithium chloride, recovering lithium chloride, supplying lithium chloride to an electrochemical cell and producing lithium hydroxide, contacting the lithium hydroxide with carbon dioxide to produce lithium carbonate.

Abstract: The invention generally relates to methods of selectively removing lithium from various liquids, methods of producing high purity lithium carbonate, methods of producing high purity lithium hydroxide, and methods of regenerating resin.

Abstract: This invention relates to a method for the selective recovery of manganese and zinc from geothermal brines that includes the steps of removing silica and iron from the brine, oxidizing the manganese and zinc to form precipitates thereof, recovering the manganese and zinc precipitates, solubilizing the manganese and zinc precipitates, purifying the manganese and zinc, and forming a manganese precipitate, and recovering the zinc by electrochemical means.

Abstract: A method for selective removal and recovery of silica and silicon containing compounds from solutions that include silica and silicon containing compounds, including geothermal brines. Also included are methods of preventing silica scale buildup in the geothermal power equipment and processes employing geothermal brines by the selective removal of silica.