Patents by Inventor Stephen HEARTY

Stephen HEARTY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • T CELL RECEPTORS AND FUSION PROTEINS THEREOF
    Publication number: 20240109950
    Abstract: The present disclosure provides T cell receptor (TCR) fusion proteins comprising a TCR that binds to a GVYDGREHTV (SEQ ID NO:34) HLA-A*02 complex that is covalently linked to a T cell engaging domain that binds a protein expressed on a cell surface of a T cell and an antibody Fc domain, as well as polynucleotides, vectors, kits, host cells, pharmaceutical compositions, methods, and uses related thereto.
    Type: Application
    Filed: December 15, 2023
    Publication date: April 4, 2024
    Applicant: Immunocore Ltd
    Inventors: Paul CONROY, Stephen HEARTY, Lok Hang MAK
  • T CELL RECEPTORS AND FUSION PROTEINS THEREOF
    Publication number: 20240092859
    Abstract: The present disclosure provides T cell receptor (TCR) fusion proteins comprising a TCR that binds to a GVYDGREHTV (SEQ ID NO:34) HLA-A*02 complex that is covalently linked to a T cell engaging domain that binds a protein expressed on a cell surface of a T cell and an antibody Fc domain, as well as polynucleotides, vectors, kits, host cells, pharmaceutical compositions, methods, and uses related thereto.
    Type: Application
    Filed: August 17, 2023
    Publication date: March 21, 2024
    Applicant: Immunocore Ltd
    Inventors: Paul CONROY, Stephen Hearty, Lok Hang Mak
  • HALF-LIFE EXTENDED IMMTAC BINDING CD3 AND A HLA-A*02 RESTRICTED PEPTIDE
    Publication number: 20220119479
    Abstract: The present invention relates to soluble multi-domain binding molecules comprising T cell receptors (TCR) having specificity for an antigen, an immunoglobulin Fc domain or an albumin-binding moiety; and an immune effector domain. Such multi-domain binding molecules are advantageous because they display improved half-life while retaining function.
    Type: Application
    Filed: January 30, 2020
    Publication date: April 21, 2022
    Inventors: Paul CONROY, Stephen HEARTY, Amandine GEORGES, Lok Hang MAK, Nikolai LISSIN, Andrew David JOHNSON, Emma HODGSON, Udofoyo UYE